Smad7 protein induces interferon regulatory factor 1-dependent transcriptional activation of caspase 8 to restore tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis (Q36579619)

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scientific article published on 19 December 2012

Language	Label	Description	Also known as
English	Smad7 protein induces interferon regulatory factor 1-dependent transcriptional activation of caspase 8 to restore tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis	scientific article published on 19 December 2012

Statements

scholarly article

1 reference

Europe PubMed Central

15 August 2017

Smad7 protein induces interferon regulatory factor 1-dependent transcriptional activation of caspase 8 to restore tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis (English)

1 reference

Europe PubMed Central

15 August 2017

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Suntaek Hong

1

1 reference

Europe PubMed Central

15 August 2017

Hye-Youn Kim

2

1 reference

Europe PubMed Central

15 August 2017

Jooyoung Kim

3

1 reference

Europe PubMed Central

15 August 2017

Huyen Trang Ha

4

1 reference

Europe PubMed Central

15 August 2017

Young-Mi Kim

5

1 reference

Europe PubMed Central

15 August 2017

Eunjin Bae

6

1 reference

Europe PubMed Central

15 August 2017

Tae Hyung Kim

7

1 reference

Europe PubMed Central

15 August 2017

Kang Choon Lee

8

1 reference

Europe PubMed Central

15 August 2017

Seong-Jin Kim

9

1 reference

Europe PubMed Central

15 August 2017

language of work or name

0 references

publication date

19 December 2012

1 reference

Europe PubMed Central

15 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

15 August 2017

288

1 reference

Europe PubMed Central

15 August 2017

5

1 reference

Europe PubMed Central

15 August 2017

3560-3570

1 reference

Europe PubMed Central

15 August 2017

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Novel HTS strategy identifies TRAIL-sensitizing compounds acting specifically through the caspase-8 apoptotic axis

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1 reference

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Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation

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SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation

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Surface TRAIL decoy receptor-4 expression is correlated with TRAIL resistance in MCF7 breast cancer cells

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Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation

1 reference

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The up-regulation of human caspase-8 by interferon-gamma in breast tumor cells requires the induction and action of the transcription factor interferon regulatory factor-1.

1 reference

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Induction and regulation of Smad7 in the gastric mucosa of patients with Helicobacter pylori infection.

1 reference

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Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter

1 reference

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Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription

1 reference

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Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation

1 reference

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X-ray crystal structure of IRF-3 and its functional implications

1 reference

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Apoptosis in podocytes induced by TGF-beta and Smad7

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Smad6 as a transcriptional corepressor

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Smad7 expression in T cells prevents colitis-associated cancer.

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Potentiation of neuroblastoma metastasis by loss of caspase-8.

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Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells

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Caspase-8 gene expression in neuroblastoma.

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Synergistic induction of apoptosis in neuroblastoma cells using a combination of cytostatic drugs with interferon-gamma and TRAIL.

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Restoration of TRAIL-induced apoptosis in a caspase-8-deficient neuroblastoma cell line by stable re-expression of caspase-8.

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1 reference

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1 reference

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Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://pubmed.ncbi.nlm.nih.gov/23255602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Smad7 inhibits the survival nuclear factor kappaB and potentiates apoptosis in epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23255602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.400408

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

1 reference

Europe PubMed Central

15 August 2017

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