Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining (Q36592709)

15 August 2017

Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining (English)

1 reference

15 August 2017

1

1 reference

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4 June 2020

Ellis C O'Neill

5

1 reference

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4 June 2020

Juan Ugalde

6

1 reference

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4 June 2020

Paul R. Jensen

7

1 reference

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4 June 2020

Bradley S. Moore

9

1 reference

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4 June 2020

author name string

Jie Li

2

1 reference

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4 June 2020

Natalie Millán-Aguiñaga

3

1 reference

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4 June 2020

Jia Jia Zhang

4

1 reference

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4 June 2020

Simone M Mantovani

8

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4 June 2020

publication date

12 October 2015

1 reference

15 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26458099%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

10

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4 June 2020

issue

12

1 reference

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4 June 2020

page(s)

2841-2849

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26458099%20AND%20SRC:MED&resulttype=core&format=json

C-S bond cleavage by a polyketide synthase domain

4 June 2020

cites work

1 reference

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Discovery of microbial natural products by activation of silent biosynthetic gene clusters

9 September 2017

1 reference

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Antibiotics. Targeting DnaN for tuberculosis therapy using novel griselimycins

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

The marine actinomycete genus Salinispora: a model organism for secondary metabolite discovery

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

How bacterial pathogens eat host lipids: implications for the development of fatty acid synthesis therapeutics

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

FabH mutations confer resistance to FabF-directed antibiotics in Staphylococcus aureus

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Mining the metabiome: identifying novel natural products from microbial communities

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

The re-emerging role of microbial natural products in antibiotic discovery

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Identifying producers of antibacterial compounds by screening for antibiotic resistance.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

A mass spectrometry-guided genome mining approach for natural product peptidogenomics

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Fix the antibiotics pipeline.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

The discovery of salinosporamide K from the marine bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Salinosporamide natural products: Potent 20 S proteasome inhibitors as promising cancer chemotherapeutics.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

New natural product biosynthetic chemistry discovered by genome mining

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Enzymatic assembly of DNA molecules up to several hundred kilobases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Antibiotics: natural products essential to human health

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

New antibiotics from bacterial natural products

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Discovery of FabH/FabF inhibitors from natural products

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Culturable marine actinomycete diversity from tropical Pacific Ocean sediments

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

OrthoMCL: Identification of Ortholog Groups for Eukaryotic Genomes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

A general cloning system to selectively isolate any eukaryotic or prokaryotic genomic region in yeast

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

A missense mutation in the fabB (beta-ketoacyl-acyl carrier protein synthase I) gene confers tiolactomycin resistance to Escherichia coli.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

The biological cost of antibiotic resistance

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Thiolactomycin resistance in Escherichia coli is associated with the multidrug resistance efflux pump encoded by emrAB

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Bacterial self-resistance to the natural proteasome inhibitor salinosporamide A.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Sampling the antibiotic resistome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

High efficiency intergeneric conjugal transfer of plasmid DNA from Escherichia coli to methyl DNA-restricting streptomycetes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Streptomyces coelicolor as an expression host for heterologous gene clusters.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Essentiality of FASII pathway for Staphylococcus aureus

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Discovery of a new peptide natural product by Streptomyces coelicolor genome mining

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Biosynthetic origins of the natural product, thiolactomycin: a unique and selective inhibitor of type II dissociated fatty acid synthases

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4758359

Thiolactomycin, a new antibiotic. II. Structure elucidation

20 September 2018

1 reference

12 December 2020

Mechanism of action of the antibiotic thiolactomycin inhibition of fatty acid synthesis of Escherichia coli

1 reference

12 December 2020

Inhibition of fatty acid synthesis by the antibiotic thiolactomycin

1 reference

12 December 2020

Acetoacetyl-acyl carrier protein synthase. A target for the antibiotic thiolactomycin

1 reference

12 December 2020

DNA sequence elements required for transcription initiation of the Schizosaccharomyces pombe ADH gene in Saccharomyces cerevisiae

1 reference

12 December 2020

Selective isolation of genomic loci from complex genomes by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae

1 reference

12 December 2020

Identification of a napsamycin biosynthesis gene cluster by genome mining

1 reference

12 December 2020

Molecular mechanisms of antibiotic resistance

1 reference

12 December 2020

A new member of the class of antibiotics with thiotetronic acid structure isolated fromStreptomyces olivaceus Tü 3010

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.1002/JLAC.198819881105

10.1021/ACSCHEMBIO.5B00658

9 March 2024

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26458099%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26458099%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

26458099

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26458099%20AND%20SRC:MED&resulttype=core&format=json