Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens (Q34173936)

31 July 2017

Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens (English)

1 reference

NPSHCJDYXPRAHR-MPUABNDYSA-N

31 July 2017

Streptomyces ambofaciens

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

Luisa Laureti

1

0 references

Bertrand Aigle

Bertrand Aigle

7

0 references

Christophe Corre

Christophe Corre

4

0 references

Pierre Leblond

Pierre Leblond

5

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Gregory L. Challis

Gregory L Challis

6

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author name string

Lijiang Song

2

1 reference

PubMed ID

21444795

31 July 2017

Sheng Huang

3

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PubMed ID

21444795

31 July 2017

language of work or name

English

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publication date

28 March 2011

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31 July 2017

6

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full work available at URL

inferred from page(s)

https://www.pnas.org/doi/pdf/10.1073/pnas.1019077108

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1073/pnas.1019077108?email=unpaywall_01@example.com

published in

Proceedings of the National Academy of Sciences of the United States of America

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31 July 2017

108

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31 July 2017

15

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31 July 2017

6258-6263

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https://api.unpaywall.org/v2/10.1073/pnas.1019077108?email=unpaywall_01@example.com

31 July 2017

1 reference

19 March 2024

access restriction status

open access

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inferred from online access status

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A tylosin ketoreductase reveals how chirality is determined in polyketides

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5 July 2018

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PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

5 July 2018

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Characterization and analysis of the PikD regulatory factor in the pikromycin biosynthetic pathway of Streptomyces venezuelae

5 July 2018

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Resistance to spiramycin in Streptomyces ambofaciens, the producer organism, involves at least two different mechanisms.

5 July 2018

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An iterative nonribosomal peptide synthetase assembles the pyrrole-amide antibiotic congocidine in Streptomyces ambofaciens.

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Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases

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Prediction and manipulation of the stereochemistry of enoylreduction in modular polyketide synthases

21 January 2018

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Biochemical evidence for an editing role of thioesterase II in the biosynthesis of the polyketide pikromycin

21 January 2018

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A subfamily of MalT-related ATP-dependent regulators in the LuxR family.

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Involvement of AlpV, a new member of the Streptomyces antibiotic regulatory protein family, in regulation of the duplicated type II polyketide synthase alp gene cluster in Streptomyces ambofaciens.

21 January 2018

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A model of structure and catalysis for ketoreductase domains in modular polyketide synthases

21 January 2018

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Increasing the efficiency of heterologous promoters in actinomycetes

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Mining microbial genomes for new natural products and biosynthetic pathways

28 October 2018

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12 December 2020

1H-NMR and 13C-NMR spectral assignments of spiramycins I and III

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12 December 2020

Mechanism and specificity of the terminal thioesterase domain from the erythromycin polyketide synthase

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12 December 2020

A chain initiation factor common to both modular and aromatic polyketide synthases

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12 December 2020

Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877

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12 December 2020

Evolution of the terminal regions of the Streptomyces linear chromosome

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1019077108

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference

PubMed ID

21444795