Intracellular signals and events activated by cytokines of the tumor necrosis factor superfamily: From simple paradigms to complex mechanisms. (Q36597952)

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scientific article published on January 2006

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English	Intracellular signals and events activated by cytokines of the tumor necrosis factor superfamily: From simple paradigms to complex mechanisms.	scientific article published on January 2006

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Intracellular signals and events activated by cytokines of the tumor necrosis factor superfamily: From simple paradigms to complex mechanisms (English)

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30 December 2019

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30 December 2019

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Sergei I Grivennikov

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Zheng-Gang Liu

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Sergei A Nedospasov

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30 December 2019

Signalling pathways of the TNF superfamily: a double-edged sword

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TNFR1- and TNFR2-mediated signaling pathways in human kidney are cell type-specific and differentially contribute to renal injury

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7 January 2021

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Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation

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7 January 2021

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Apoptosis control by death and decoy receptors

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7 January 2021

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Toll-like receptor signaling pathways

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7 January 2021

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Convergent evolution of cytokines

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7 January 2021

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Functional convergence of invertebrate and vertebrate cytokine-like molecules based on a similar lectin-like activity.

1 reference

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Receptor-mediated choreography of life and death.

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The multifaceted roles of TRAFs in the regulation of B-cell function.

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The two NF-kappaB activation pathways and their role in innate and adaptive immunity

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Signaling through the lymphotoxin beta receptor induces the death of some adenocarcinoma tumor lines

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NF-kappa B activation by tumor necrosis factor and interleukin-1.

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A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling

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7 January 2021

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Mammalian MAP kinase signalling cascades

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7 January 2021

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Lymphotoxin beta receptor induces interleukin 8 gene expression via NF-kappaB and AP-1 activation

1 reference

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7 January 2021

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The E3 ubiquitin ligase itch couples JNK activation to TNFalpha-induced cell death by inducing c-FLIP(L) turnover

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7 January 2021

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Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway

1 reference

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7 January 2021

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Activation of the NF-kappaB pathway by caspase 8 and its homologs

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7 January 2021

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TNF-R1 signaling: a beautiful pathway

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7 January 2021

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Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis

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A co-evolution perspective of the TNFSF and TNFRSF families in the immune system

1 reference

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7 January 2021

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A lymphotoxin-beta-specific receptor

1 reference

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7 January 2021

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Signal transduction by the JNK group of MAP kinases

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7 January 2021

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The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

1 reference

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7 January 2021

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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

1 reference

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7 January 2021

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A JNK-Dependent Pathway Is Required for TNFα-Induced Apoptosis

1 reference

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7 January 2021

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Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist.

1 reference

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7 January 2021

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X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling

1 reference

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7 January 2021

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TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death

1 reference

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7 January 2021

based on heuristic

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Apparently normal tumor necrosis factor receptor 1 signaling in the absence of the silencer of death domains

1 reference

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7 January 2021

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Insights into programmed cell death through structural biology

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7 January 2021

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TNFRSF1A mutations and autoinflammatory syndromes

1 reference

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7 January 2021

based on heuristic

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Regulating the regulators: control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Missing pieces in the NF-kappaB puzzle

1 reference

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7 January 2021

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inferred from DOI database lookup

The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase

1 reference

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7 January 2021

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TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs

1 reference

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7 January 2021

based on heuristic

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Gene defect in ectodermal dysplasia implicates a death domain adapter in development

1 reference

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7 January 2021

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The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games

1 reference

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7 January 2021

based on heuristic

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Role of TNF receptor-associated factor 2 in the activation of IgM secretion by CD40 and CD120b

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

1 reference

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7 January 2021

based on heuristic

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TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

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7 January 2021

based on heuristic

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Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5

1 reference

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7 January 2021

based on heuristic

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Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway

1 reference

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7 January 2021

based on heuristic

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The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1 reference

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7 January 2021

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Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

1 reference

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7 January 2021

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A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes

1 reference

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7 January 2021

based on heuristic

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Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling

1 reference

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7 January 2021

based on heuristic

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Caspase-8 serves both apoptotic and nonapoptotic roles

1 reference

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7 January 2021

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1 reference

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7 January 2021

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1 reference

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7 January 2021

based on heuristic

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1 reference

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7 January 2021

based on heuristic

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The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

1 reference

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7 January 2021

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1 reference

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7 January 2021

based on heuristic

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Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

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7 January 2021

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7 January 2021

based on heuristic

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Death receptor signaling

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7 January 2021

based on heuristic

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1 reference

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7 January 2021

based on heuristic

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Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

1 reference

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7 January 2021

based on heuristic

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The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

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1 reference

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7 January 2021

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1 reference

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7 January 2021

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TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

1 reference

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7 January 2021

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1 reference

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7 January 2021

based on heuristic

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Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The death domain kinase RIP is essential for TRAIL (Apo2L)-induced activation of IkappaB kinase and c-Jun N-terminal kinase

1 reference

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7 January 2021

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1 reference

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7 January 2021

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inferred from DOI database lookup

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

1 reference

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7 January 2021

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inferred from DOI database lookup

The TNF and TNF receptor superfamilies: integrating mammalian biology

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

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1 reference

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7 January 2021

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Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes.

1 reference

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7 January 2021

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1 reference

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7 January 2021

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1 reference

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7 January 2021

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7 January 2021

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1 reference

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7 January 2021

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TAB2, TRAF6 and TAK1 are involved in NF-κB activation induced by the TNF-receptor, Edar and its adaptator Edaradd

1 reference

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7 January 2021

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An atypical tumor necrosis factor (TNF) receptor-associated factor-binding motif of B cell-activating factor belonging to the TNF family (BAFF) receptor mediates induction of the noncanonical NF-kappaB signaling pathway.

1 reference

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7 January 2021

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Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Fas ligand-induced apoptosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation

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7 January 2021

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Identification and functional characterization of DR6, a novel death domain-containing TNF receptor

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7 January 2021

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Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesis

1 reference

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7 January 2021

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Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

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7 January 2021

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Expression and regulation of tumor necrosis factor in macrophages from cystic fibrosis patients

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7 January 2021

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Ligand-induced formation of p55 and p75 tumor necrosis factor receptor heterocomplexes on intact cells

1 reference

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based on heuristic

inferred from DOI database lookup

Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The crystal structure of the Bacillus anthracis spore surface protein BclA shows remarkable similarity to mammalian proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Essential function for the kinase TAK1 in innate and adaptive immune responses.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis signaling in lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Lymphotoxin and LIGHT signaling pathways and target genes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

AP-1 as a regulator of cell life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Essential roles of receptor-interacting protein and TRAF2 in oxidative stress-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The membrane-bound but not the soluble form of human Fas ligand is responsible for its inflammatory activity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of apoptosis by X-linked ectodermal dysplasia receptor via a caspase 8-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Membrane Fas ligand kills human peripheral blood T lymphocytes, and soluble Fas ligand blocks the killing

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of SODD in Regulation of Tumor Necrosis Factor Responses

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of JNK activation through NF-kappaB target genes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Two TNF receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Dissecting the role of lymphotoxin in lymphoid organs by conditional targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Lymphotoxin-beta receptor signaling complex: role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor: an apoptosis JuNKie?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor receptor and Fas signaling mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

TNF/TNFR family members in costimulation of T cell responses

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The LIGHT and DARC sides of herpesvirus entry mediator

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The essential role of MEKK3 in TNF-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

AIP1 mediates TNF-alpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

TNF ligands: is TALL-1 a trimer or a virus-like cluster?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2952002-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0074-7696(06)52002-9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984817%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16984817%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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