The role of BRCA1 in transcriptional regulation and cell cycle control (Q36602565)

15 August 2017

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title

The role of BRCA1 in transcriptional regulation and cell cycle control (English)

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15 August 2017

P B Mullan

1

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15 August 2017

J E Quinn

series ordinal

2

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15 August 2017

D P Harkin

series ordinal

3

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15 August 2017

language of work or name

English

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publication date

1 September 2006

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15 August 2017

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15 August 2017

25

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15 August 2017

5854-5863

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15 August 2017

43

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209872

15 August 2017

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cites work

Cell cycle dysregulation by green tea polyphenol epigallocatechin-3-gallate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Attenuation of estrogen receptor alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 regulates the interferon gamma-mediated apoptotic response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 is a selective co-activator of 14-3-3 sigma gene transcription in mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

IGF-1 down-regulates IFN-gamma R2 chain surface expression and desensitizes IFN-gamma/STAT-1 signaling in human T lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Germline BRCA1/2 mutations and p27(Kip1) protein levels independently predict outcome after breast cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Rb-associated protein 46 (RbAp46) inhibits transcriptional transactivation mediated by BRCA1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Role of direct interaction in BRCA1 inhibition of estrogen receptor activity

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 Inhibition of Estrogen Receptor Signaling in Transfected Cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 regulates GADD45 through its interactions with the OCT-1 and CAAT motifs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

DNA damage induces p53-dependent BRCA1 nuclear export

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 interacts with and is required for paclitaxel-induced activation of mitogen-activated protein kinase kinase kinase 3.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Activation of transcription in vitro by the BRCA1 carboxyl-terminal domain

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Breast cancer: hormones and other risk factors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Human BRCA1 inhibits growth in yeast: potential use in diagnostic testing

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 activation of the GADD45 promoter.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Functional selectivity of recombinant mammalian SWI/SNF subunits

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Direct interaction between BRCA1 and the estrogen receptor regulates vascular endothelial growth factor (VEGF) transcription and secretion in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 and c-Myc associate to transcriptionally repress psoriasin, a DNA damage-inducible gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 Associates with Processive RNA Polymerase II

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Repression of BRCA1 through a feedback loop involving p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 effects on the cell cycle and the DNA damage response are linked to altered gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 can modulate RNA polymerase II carboxy-terminal domain phosphorylation levels

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Evidence for a transcriptional activation function of BRCA1 C-terminal region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Brca1 controls homology-directed DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

The 2,5 oligoadenylate synthetase/RNaseL pathway is a novel effector of BRCA1- and interferon-gamma-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

CBP/p300 interact with and function as transcriptional coactivators of BRCA1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 inhibits membrane estrogen and growth factor receptor signaling to cell proliferation in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Repression of mRNA for the PLK cell cycle gene after DNA damage requires BRCA1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Interaction between a cellular protein that binds to the C-terminal region of adenovirus E1A (CtBP) and a novel cellular protein is disrupted by E1A through a conserved PLDLS motif

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 is a component of the RNA polymerase II holoenzyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 signals ARF-dependent stabilization and coactivation of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1/BARD1 ubiquitinate phosphorylated RNA polymerase II.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Tetrameric oligomerization mediates transcriptional repression by the BRCA1-dependent Kruppel-associated box-zinc finger protein ZBRK1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Functional dissection of transcription factor ZBRK1 reveals zinc fingers with dual roles in DNA-binding and BRCA1-dependent transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 function mediates a TRAP/DRIP complex through direct interaction with TRAP220

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Cyclin D1 antagonizes BRCA1 repression of estrogen receptor alpha activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

GADD45 induction of a G2/M cell cycle checkpoint

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 transcriptionally regulates genes involved in breast tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Structural consequences of a cancer-causing BRCA1-BRCT missense mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Characterization of a carboxy-terminal BRCA1 interacting protein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Effect of DNA damage on a BRCA1 complex

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 Inhibition of Telomerase Activity in Cultured Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Regulation of the estrogen-inducible gene expression profile by the breast cancer susceptibility gene BRCA1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 interacts with components of the histone deacetylase complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Degradation of Transcription Repressor ZBRK1 through the Ubiquitin-Proteasome Pathway Relieves Repression of Gadd45a upon DNA Damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

BRCA1 facilitates microhomology-mediated end joining of DNA double strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209872

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209872

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Dimensions Publication ID

15 August 2017

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1 reference