New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells. (Q36603335)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22831834%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells (English)

1 reference

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9 February 2020

1 reference

5

1 reference

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9 February 2020

author name string

Soo Ok Lee

1

1 reference

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9 February 2020

Zhifang Ma

2

1 reference

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9 February 2020

Chiuan-Ren Yeh

3

1 reference

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9 February 2020

Jie Luo

4

1 reference

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9 February 2020

Kuo-Pao Lai

6

1 reference

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9 February 2020

Shinichi Yamashita

7

1 reference

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9 February 2020

Liang Liang

8

1 reference

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9 February 2020

Jing Tian

9

1 reference

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9 February 2020

Lei Li

10

1 reference

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9 February 2020

Qi Jiang

11

1 reference

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9 February 2020

Chiung-Kuei Huang

12

1 reference

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9 February 2020

Yuanjie Niu

13

1 reference

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9 February 2020

Shuyuan Yeh

14

1 reference

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9 February 2020

Chawnshang Chang

15

1 reference

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9 February 2020

publication date

24 July 2012

1 reference

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Journal of Molecular Cell Biology

9 February 2020

published in

1 reference

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9 February 2020

volume

5

1 reference

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9 February 2020

issue

1

1 reference

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9 February 2020

page(s)

14-26

1 reference

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New therapeutic approach to suppress castration-resistant prostate cancer using ASC-J9 via targeting androgen receptor in selective prostate cells

9 February 2020

cites work

1 reference

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Increased CK5/CK8-positive intermediate cells with stromal smooth muscle cell atrophy in the mice lacking prostate epithelial androgen receptor

30 September 2017

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Tocotrienols inhibit AKT and ERK activation and suppress pancreatic cancer cell proliferation by suppressing the ErbB2 pathway

30 September 2017

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Concise review: Emerging concepts in clinical targeting of cancer stem cells

30 September 2017

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Prostate cancer stem cells and their potential roles in metastasis

30 September 2017

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Targeting the PI3K/Akt/mTOR pathway--beyond rapalogs

30 September 2017

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Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signalling

30 September 2017

1 reference

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Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells

30 September 2017

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Therapeutic targeting of the prostate cancer microenvironment

30 September 2017

1 reference

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Gamma-tocotrienol as an effective agent in targeting prostate cancer stem cell-like population.

30 September 2017

1 reference

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Genomic profiling of tumor initiating prostatospheres

30 September 2017

1 reference

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Androgen receptor promotes hepatitis B virus-induced hepatocarcinogenesis through modulation of hepatitis B virus RNA transcription

30 September 2017

1 reference

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CD133+ cells from medulloblastoma and PNET cell lines are more resistant to cyclopamine inhibition of the sonic hedgehog signaling pathway than CD133- cells

30 September 2017

1 reference

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Cancer stem cells as new therapeutic target to prevent tumour progression and metastasis

30 September 2017

1 reference

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Tumor-stroma co-evolution in prostate cancer progression and metastasis

30 September 2017

1 reference

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Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-alpha expression

30 September 2017

1 reference

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Effects of LY294002 on the invasiveness of human gastric cancer in vivo in nude mice

30 September 2017

1 reference

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The role of the intravascular microenvironment in spontaneous metastasis development

30 September 2017

1 reference

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aPKClambda/iota promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6.

30 September 2017

1 reference

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A luminal epithelial stem cell that is a cell of origin for prostate cancer

30 September 2017

1 reference

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Akt1 and akt2 play distinct roles in the initiation and metastatic phases of mammary tumor progression

30 September 2017

1 reference

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Development of a second-generation antiandrogen for treatment of advanced prostate cancer

30 September 2017

1 reference

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Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells

30 September 2017

1 reference

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Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature

30 September 2017

1 reference

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Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach

30 September 2017

1 reference

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Stem cell characteristics in prostate cancer cell lines

30 September 2017

1 reference

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The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

30 September 2017

1 reference

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Oncogenic activation of androgen receptor

30 September 2017

1 reference

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The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cells

30 September 2017

1 reference

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Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma.

30 September 2017

1 reference

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Prostate cancer stem cells: a new target for therapy

30 September 2017

1 reference

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Prostate stem cells and benign prostatic hyperplasia

30 September 2017

1 reference

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The androgen receptor as putative therapeutic target in hormone-refractory prostate cancer

30 September 2017

1 reference

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Self-renewal and multilineage differentiation in vitro from murine prostate stem cells.

30 September 2017

1 reference

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Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44+alpha2beta1+ cell population is enriched in tumor-initiating cells

30 September 2017

1 reference

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Tocotrienols potentiate lovastatin-mediated growth suppression in vitro and in vivo

30 September 2017

1 reference

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Interleukin-6 undergoes transition from growth inhibitor associated with neuroendocrine differentiation to stimulator accompanied by androgen receptor activation during LNCaP prostate cancer cell progression

30 September 2017

1 reference

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ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor

30 September 2017

1 reference

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Isolation and functional characterization of murine prostate stem cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570051

gamma-Tocotrienol inhibits ErbB3-dependent PI3K/Akt mitogenic signalling in neoplastic mammary epithelial cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570051

Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications

30 September 2017

1 reference

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The Sca-1 cell surface marker enriches for a prostate-regenerating cell subpopulation that can initiate prostate tumorigenesis

30 September 2017

1 reference

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Requirement for NF-(kappa)B in interleukin-4-induced androgen receptor activation in prostate cancer cells.

30 September 2017

1 reference

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Interleukin-6 is a potent inducer of S100P, which is up-regulated in androgen-refractory and metastatic prostate cancer

30 September 2017

1 reference

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CD133, a novel marker for human prostatic epithelial stem cells.

30 September 2017

1 reference

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Is the Achilles' heel for prostate cancer therapy a gain of function in androgen receptor signaling?

30 September 2017

1 reference

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Stem cell differentiation within the human prostate epithelium: implications for prostate carcinogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570051

In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002).

30 September 2017

1 reference

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The role of androgen in determining differentiation and regulation of androgen receptor expression in the human prostatic epithelium transient amplifying population

30 September 2017

1 reference

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Identification and isolation of human prostate epithelial stem cells based on alpha(2)beta(1)-integrin expression.

28 June 2018

1 reference

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A phase II study of 5-aza-2'deoxycytidine (decitabine) in hormone independent metastatic (D2) prostate cancer.

28 June 2018

1 reference

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Expression of androgen receptor mRNA during mouse embryogenesis.

28 June 2018

1 reference

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Androgen receptors in endocrine-therapy-resistant human prostate cancer.

28 June 2018

1 reference

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Colocalization of basal and luminal cell-type cytokeratins in human prostate cancer

28 June 2018

1 reference

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A novel mechanism of natural vitamin E tocotrienol activity: involvement of ERbeta signal transduction.

28 June 2018

1 reference

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WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570051

Promotion of bladder cancer development and progression by androgen receptor signals.

20 September 2018

1 reference

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Inhibition of Akt by the alkylphospholipid perifosine does not enhance the radiosensitivity of human glioma cells.

20 September 2018

1 reference

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Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3570051

Steroid 5alpha-reductase isozymes I and II in recurrent prostate cancer

20 September 2018

1 reference

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Molecular mechanisms involved in hormone resistance of prostate cancer

20 September 2018

1 reference

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Activation of Akt-1 (PKB-alpha) can accelerate ErbB-2-mediated mammary tumorigenesis but suppresses tumor invasion

20 September 2018

1 reference

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Establishment and characterization of androgen-independent human prostate cancer LNCaP cell model

20 September 2018

1 reference

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The change in the dihydrotestosterone level in the prostate before and after androgen deprivation therapy in connection with prostate cancer aggressiveness using the Gleason score

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22831834

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22831834

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines and in prostate cancer specimens

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22831834

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/JMCB/MJS042

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22831834%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22831834%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22831834%20AND%20SRC:MED&resulttype=core&format=json