Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism? (Q36613598)

15 August 2017

Trastuzumab-based treatment of HER2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism? (English)

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Frédérique Penault-Llorca

15 August 2017

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3

object named as

F Penault-Llorca

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Bruno Coudert

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author name string

L Arnould

1

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15 August 2017

M Gelly

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15 August 2017

L Benoit

4

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15 August 2017

F Bonnetain

5

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15 August 2017

C Migeon

6

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15 August 2017

V Cabaret

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15 August 2017

V Fermeaux

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15 August 2017

P Bertheau

9

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15 August 2017

J Garnier

10

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15 August 2017

J-F Jeannin

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15 August 2017

B Coudert

12

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15 August 2017

language of work or name

English

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publication date

1 January 2006

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British Journal of Cancer

15 August 2017

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15 August 2017

94

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2

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15 August 2017

259-267

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https://scigraph.springernature.com/pub.10.1038/sj.bjc.6602930

15 August 2017

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cites work

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HER2-specific cytotoxic activity of lymphokine-activated killer cells in the presence of trastuzumab.

30 September 2017

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Neoadjuvant trastuzumab induces apoptosis in primary breast cancers

30 September 2017

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Future options with trastuzumab for primary systemic and adjuvant therapy

30 September 2017

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Blockade of epidermal growth factor- or heregulin-dependent ErbB2 activation with the anti-ErbB2 monoclonal antibody 2C4 has divergent downstream signaling and growth effects

30 September 2017

1 reference

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Combination of adoptive immunotherapy with Herceptin for patients with HER2-expressing breast cancer.

30 September 2017

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The Her-2/neu gene and protein in breast cancer 2003: biomarker and target of therapy

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30 September 2017

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30 September 2017

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Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells

30 September 2017

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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

30 September 2017

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Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets

30 September 2017

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Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease

30 September 2017

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Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers

30 September 2017

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The biology of erbB-2/neu/HER-2 and its role in cancer

30 September 2017

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

30 September 2017

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The role of cyclin-dependent kinase inhibitor p27Kip1 in anti-HER2 antibody-induced G1 cell cycle arrest and tumor growth inhibition

30 September 2017

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Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action

28 June 2018

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Amplification of a novel v-erbB-related gene in a human mammary carcinoma.

28 June 2018

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Prognostic importance of c-erbB-2 expression in breast cancer. International (Ludwig) Breast Cancer Study Group.

28 June 2018

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Pre-operative systemic (neo-adjuvant) therapy with trastuzumab and docetaxel for HER2-overexpressing stage II or III breast cancer: results of a multicenter phase II trial

28 June 2018

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Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer

20 September 2018

1 reference

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HER2 amplification ratios by fluorescence in situ hybridization and correlation with immunohistochemistry in a cohort of 6556 breast cancer tissues.

20 September 2018

1 reference

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Neoadjuvant trastuzumab and docetaxel in breast cancer: preliminary results

20 September 2018

1 reference

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Trastuzumab and interleukin-2 in HER2-positive metastatic breast cancer: a pilot study.

20 September 2018

1 reference

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Preoperative therapy with trastuzumab and paclitaxel followed by sequential adjuvant doxorubicin/cyclophosphamide for HER2 overexpressing stage II or III breast cancer: a pilot study.

20 September 2018

1 reference

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Interleukin-2 enhances the natural killer cell response to Herceptin-coated Her2/neu-positive breast cancer cells

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361112

Natural killer cell cytotoxicity of breast cancer targets is enhanced by two distinct mechanisms of antibody-dependent cellular cytotoxicity against LFA-3 and HER2/neu.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2361112

Pilot Study of the Mechanism of Action of Preoperative Trastuzumab in Patients with Primary Operable Breast Tumors Overexpressing HER2

20 September 2018

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12 December 2020

Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer

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12 December 2020

Pathologic response to induction chemotherapy in locally advanced carcinoma of the breast: a determinant of outcome

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12 December 2020

Bispecific minibodies targeting HER2/neu and CD16 exhibit improved tumor lysis when placed in a divalent tumor antigen binding format

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJC.6602930

1 reference

15 August 2017

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15 August 2017

1 reference