Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity. (Q36633152)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18276636%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity (English)

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2 January 2020

1

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2 January 2020

John Mcdonald

2

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2 January 2020

J Tyson McDonald

3

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2 January 2020

Thomas A Kunkel

5

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2 January 2020

author name string

Christopher K Mathews

4

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2 January 2020

language of work or name

English

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publication date

14 February 2008

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2 January 2020

number of pages

8

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inferred from page(s)

published in

Nucleic Acids Research

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2 January 2020

volume

36

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2 January 2020

issue

7

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2 January 2020

page(s)

2174-2181

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The DNA polymerase gamma Y955C disease variant associated with PEO and parkinsonism mediates the incorporation and translesion synthesis opposite 7,8-dihydro-8-oxo-2'-deoxyguanosine

2 January 2020

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30 September 2017

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30 September 2017

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30 September 2017

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Mitochondrial deoxyribonucleotides, pool sizes, synthesis, and regulation

30 September 2017

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An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress

30 September 2017

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Erroneous incorporation of oxidized DNA precursors by Y-family DNA polymerases

30 September 2017

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Structure of DNA polymerase beta with the mutagenic DNA lesion 8-oxodeoxyguanine reveals structural insights into its coding potential

30 September 2017

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Active site mutation in DNA polymerase gamma associated with progressive external ophthalmoplegia causes error-prone DNA synthesis

30 September 2017

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The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance

30 September 2017

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Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication

30 September 2017

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Mitochondrial diseases in man and mouse

30 September 2017

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Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

30 September 2017

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Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of the enzyme in mitochondria

30 September 2017

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Mouse MTH1 protein with 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphatase activity that prevents transversion mutation. cDNA cloning and tissue distribution

30 September 2017

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Mismatch-specific 3'----5' exonuclease associated with the mitochondrial DNA polymerase from Drosophila embryos

30 September 2017

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Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine

30 September 2017

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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

30 September 2017

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Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: sanitization of nucleotide pool

30 September 2017

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30 September 2017

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A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine

30 September 2017

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20 September 2018

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20 September 2018

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20 September 2018

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20 September 2018

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Characterization of the native and recombinant catalytic subunit of human DNA polymerase gamma: identification of residues critical for exonuclease activity and dideoxynucleotide sensitivity

20 September 2018

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DNA replication fidelity with 8-oxodeoxyguanosine triphosphate.

20 September 2018

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Exonucleolytic proofreading by a mammalian DNA polymerase

20 September 2018

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12 December 2020

Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases

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12 December 2020

Incorporation and replication of 8-oxo-deoxyguanosine by the human mitochondrial DNA polymerase

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12 December 2020

The fidelity of human DNA polymerase gamma with and without exonucleolytic proofreading and the p55 accessory subunit

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12 December 2020

Exonucleolytic proofreading enhances the fidelity of DNA synthesis by chick embryo DNA polymerase-gamma

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKN062

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18276636%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18276636%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

PubMed publication ID

18276636

1 reference