Transcriptional regulation via the NF-kappaB signaling module. (Q36637878)

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21 December 2019

review article

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title

Transcriptional regulation via the NF-kappaB signaling module (English)

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21 December 2019

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2

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21 December 2019

author name string

Hoffmann A

series ordinal

1

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21 December 2019

Ghosh G

series ordinal

3

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21 December 2019

language of work or name

English

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publication date

1 October 2006

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21 December 2019

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21 December 2019

volume

25

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21 December 2019

issue

51

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21 December 2019

page(s)

6706-6716

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209933

21 December 2019

exact match

0 references

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The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site

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7 January 2021

Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers

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A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kappaB-dependent gene activity

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Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.

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Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views

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Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA

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A novel DNA recognition mode by the NF-kappa B p65 homodimer

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NF-kappaB p65 (RelA) homodimer uses distinct mechanisms to recognize DNA targets

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The kappa B DNA sequence from the HIV long terminal repeat functions as an allosteric regulator of HIV transcription

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Transient IkappaB kinase activity mediates temporal NF-kappaB dynamics in response to a wide range of tumor necrosis factor-alpha doses

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Achieving stability of lipopolysaccharide-induced NF-kappaB activation

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Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution

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7 January 2021

Functionally distinct NF-kappa B binding sites in the immunoglobulin kappa and IL-2 receptor alpha chain genes

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7 January 2021

The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

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7 January 2021

RelB/p50 Dimers Are Differentially Regulated by Tumor Necrosis Factor-α and Lymphotoxin-β Receptor Activation

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7 January 2021

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

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7 January 2021

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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7 January 2021

The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers

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7 January 2021

A compendium of signals and responses triggered by prodeath and prosurvival cytokines

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7 January 2021

Unravelling the complexities of the NF-kappaB signalling pathway using mouse knockout and transgenic models.

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7 January 2021

Structure of NF-kappa B p50 homodimer bound to a kappa B site

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7 January 2021

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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7 January 2021

Limiting inflammatory responses during activation of innate immunity

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7 January 2021

Analysis of the NF-kappaB p50 dimer interface by diversity screening

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7 January 2021

Circuitry of nuclear factor kappaB signaling

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7 January 2021

Genetic analysis of NF- B/Rel transcription factors defines functional specificities

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7 January 2021

The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

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7 January 2021

X-ray crystal structure of proto-oncogene product c-Rel bound to the CD28 response element of IL-2

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7 January 2021

The role of DNA in the mechanism of NFkappaB dimer formation: crystal structures of the dimerization domains of the p50 and p65 subunits

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7 January 2021

Crystal structure of a free kappaB DNA: insights into DNA recognition by transcription factor NF-kappaB.

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7 January 2021

NF-kappaB RelB forms an intertwined homodimer

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7 January 2021

Structure and mechanism in NF-kappa B/I kappa B signaling

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7 January 2021

RelA repression of RelB activity induces selective gene activation downstream of TNF receptors

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7 January 2021

The response of human epithelial cells to TNF involves an inducible autocrine cascade

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7 January 2021

IkappaBepsilon provides negative feedback to control NF-kappaB oscillations, signaling dynamics, and inflammatory gene expression.

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7 January 2021

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression

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7 January 2021

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation

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7 January 2021

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

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7 January 2021

One nucleotide in a kappaB site can determine cofactor specificity for NF-kappaB dimers

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7 January 2021

Quantitative high-throughput analysis of transcription factor binding specificities.

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7 January 2021

X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex

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7 January 2021

Structure and function of the interferon-beta enhanceosome

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7 January 2021

Distribution of NF-kappaB-binding sites across human chromosome 22

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7 January 2021

Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Structure of the NF-kappa B p50 homodimer bound to DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Coordination of a transcriptional switch by HMGI(Y) acetylation

1 reference

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7 January 2021

Oscillations in NF-kappaB signaling control the dynamics of gene expression

1 reference

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7 January 2021

Molecular determinants of crosstalk between nuclear receptors and toll-like receptors.

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7 January 2021

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

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7 January 2021

Discreet mutations from c-Rel to v-Rel alter kappaB DNA recognition, IkappaBalpha binding, and dimerization: implications for v-Rel oncogenicity

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7 January 2021

Mechanism of I kappa B alpha binding to NF-kappa B dimers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Mechanism of kappa B DNA binding by Rel/NF-kappa B dimers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Transcriptional activation by recruitment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Characterization of elements determining the dimerization properties of RelB and p50.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Degradation of promoter-bound p65/RelA is essential for the prompt termination of the nuclear factor kappaB response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Two waves of nuclear factor kappaB recruitment to target promoters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Modulation of NF-kappaB activity by exchange of dimers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Coordinated binding of NF-kappaB family members in the response of human cells to lipopolysaccharide.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Characterization of the dimer interface of transcription factor NFkappaB p50 homodimer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Immunity regulatory DNAs share common organizational features in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Triggering the interferon antiviral response through an IKK-related pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

RelB cellular regulation and transcriptional activity are regulated by p100.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

How NF-κB can be attracted by its cognate DNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Solution structure of a non-palindromic 16 base-pair DNA related to the HIV-1 kappa B site: evidence for BI-BII equilibrium inducing a global dynamic curvature of the duplex

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Quantitative prediction of NF-kappa B DNA-protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Stimulus specificity of gene expression programs determined by temporal control of IKK activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Interferon regulatory factor-3-mediated activation of the interferon-sensitive response element by Toll-like receptor (TLR) 4 but not TLR3 requires the p65 subunit of NF-kappa.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209933

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209933

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17072323%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference