Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system (Q36638792)

15 August 2017

Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system (English)

1 reference

15 August 2017

Bernhard Schmierer

1

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Caroline S. Hill

object named as

Caroline S Hill

series ordinal

4

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Paul A. Bates

object named as

Paul A Bates

series ordinal

3

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author name string

Alexander L Tournier

series ordinal

2

1 reference

PMCID

2373357

15 August 2017

language of work or name

English

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publication date

28 April 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

15 August 2017

1 reference

15 August 2017

105

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15 August 2017

18

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15 August 2017

6608-6613

1 reference

PMCID

2373357

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2373357/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

1 reference

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Constraint-based modeling and kinetic analysis of the Smad dependent TGF-beta signaling pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373357

Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads

30 September 2017

1 reference

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Physicochemical modelling of cell signalling pathways.

30 September 2017

1 reference

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COPASI--a COmplex PAthway SImulator

30 September 2017

1 reference

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Quantitative models of developmental pattern formation

30 September 2017

1 reference

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Signal processing in the TGF-beta superfamily ligand-receptor network

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373357

Smad transcription factors

30 September 2017

1 reference

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Kinetic analysis of Smad nucleocytoplasmic shuttling reveals a mechanism for transforming growth factor beta-dependent nuclear accumulation of Smads

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373357

Specificity and versatility in tgf-beta signaling through Smads

30 September 2017

1 reference

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Nuclear targeting of transforming growth factor-beta-activated Smad complexes

30 September 2017

1 reference

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GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor

30 September 2017

1 reference

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

30 September 2017

1 reference

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Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373357

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

30 September 2017

1 reference

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Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta1 and Ran-dependent manner

30 September 2017

1 reference

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Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

30 September 2017

1 reference

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Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373357

Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor beta

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373357

Kinesin-mediated transport of Smad2 is required for signaling in response to TGF-beta ligands.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373357

Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373357

Postsynaptic mad signaling at the Drosophila neuromuscular junction.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373357

Analysis of Smad nucleocytoplasmic shuttling in living cells.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373357

Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2373357

20 September 2018

Identifiers

DOI

10.1073/PNAS.0710134105

1 reference

15 August 2017

0 references

1 reference

15 August 2017

1 reference

PMCID

2373357