Hypertension pharmacogenomics: in search of personalized treatment approaches (Q36652960)

15 August 2017

Hypertension pharmacogenomics: in search of personalized treatment approaches (English)

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15 August 2017

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Rhonda M Cooper-DeHoff

series ordinal

1

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PMCID

4778736

15 August 2017

Julie A Johnson

series ordinal

2

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PMCID

4778736

15 August 2017

language of work or name

English

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publication date

23 November 2015

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Nature Reviews Nephrology

15 August 2017

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15 August 2017

12

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15 August 2017

2

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15 August 2017

110-122

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https://scigraph.springernature.com/pub.10.1038/nrneph.2015.176

15 August 2017

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G-protein-coupled receptor kinase 4 polymorphisms and blood pressure response to metoprolol among African Americans: sex-specificity and interactions

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Genomic association analysis suggests chromosome 12 locus influencing antihypertensive response to thiazide diuretic

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Association of NEDD4L ubiquitin ligase with essential hypertension

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Diuretic therapy, the alpha-adducin gene variant, and the risk of myocardial infarction or stroke in persons with treated hypertension

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C825T polymorphism of the G protein beta(3)-subunit and antihypertensive response to a thiazide diuretic

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An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels

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Multilocus genetic risk scores for coronary heart disease prediction

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G-protein receptor kinase 4 polymorphism and response to antihypertensive therapy.

20 September 2018

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Association of common polymorphisms in β1-adrenergic receptor with antihypertensive response to carvedilol.

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Effects of ACE and ADD1 gene polymorphisms on blood pressure response to hydrochlorothiazide: a meta-analysis

20 September 2018

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Adrenergic receptor polymorphisms and prevention of ventricular arrhythmias with bucindolol in patients with chronic heart failure

20 September 2018

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Trends in antihypertensive medication use and blood pressure control among United States adults with hypertension: the National Health And Nutrition Examination Survey, 2001 to 2010.

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Effect of ACE insertion/deletion and 12 other polymorphisms on clinical outcomes and response to treatment in the LIFE study

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A functional variant of NEDD4L is associated with hypertension, antihypertensive response, and orthostatic hypotension.

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Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension

20 September 2018

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Choice of first antihypertensive: simple as ABCD?

20 September 2018

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beta1-Adrenergic receptor polymorphisms influence the response to metoprolol monotherapy in patients with essential hypertension.

20 September 2018

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Hydrochlorothiazide efficacy and polymorphisms in ACE, ADD1 and GNB3 in healthy, male volunteers.

20 September 2018

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Elevated blood pressure and risk of end-stage renal disease in subjects without baseline kidney disease

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The thiazide-sensitive Na(+)-Cl(-) cotransporter gene, C1784T, and adrenergic receptor-beta3 gene, T727C, may be gene polymorphisms susceptible to the antihypertensive effect of thiazide diuretics.

20 September 2018

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Beta1-adrenergic receptor gene polymorphisms and response to beta1-adrenergic receptor blockade in patients with essential hypertension

20 September 2018

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Angiotensinogen gene polymorphisms: relationship to blood pressure response to antihypertensive treatment. Results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation vs Atenolol (SILVHIA) trial

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Association between a polymorphism in the G protein beta3 subunit gene and lower renin and elevated diastolic blood pressure levels.

20 September 2018

1 reference

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Blood pressure lowering and cardiovascular risk – Authors' reply

20 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

ACE and α-Adducin Polymorphism as Markers of Individual Response to Diuretic Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

Interaction between polymorphisms in the renin–angiotensin–system and angiotensin-converting enzyme inhibitor or β-blocker use and the risk of myocardial infarction and stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

US trends in prevalence, awareness, treatment, and control of hypertension, 1988-2008

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

Genetic variation in NEDD4L, an epithelial sodium channel regulator, is associated with cardiovascular disease and cardiovascular death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

The gain-of-function G389R variant of the beta1-adrenoceptor does not influence blood pressure or heart rate response to beta-blockade in hypertensive subjects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

beta1- and beta2-adrenergic receptor gene variation, beta-blocker use and risk of myocardial infarction and stroke

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

Interactions between five candidate genes and antihypertensive drug therapy on blood pressure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

α-Adducin 460Trp Allele Is Associated With Erythrocyte Na Transport Rate in North Sardinian Primary Hypertensives

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

The role of alpha-adducin polymorphism in blood pressure and sodium handling regulation may not be excluded by a negative association study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

Effects of endothelial nitric oxide synthase, α-adducin, and other candidate gene polymorphisms on blood pressure response to hydrochlorothiazide

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

The influence of the alpha-adducin G460W polymorphism and angiotensinogen M235T polymorphism on antihypertensive medication and blood pressure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

A core promoter variant of angiotensinogen gene and interindividual variation in response to angiotensin-converting enzyme inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

Association of angiotensinogen (M235T) gene polymorphism with blood pressure lowering response to angiotensin converting enzyme inhibitor (Enalapril)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

Contribution of angiotensin I converting enzyme gene polymorphism and angiotensinogen gene polymorphism to blood pressure regulation in essential hypertension

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

Genetic variation in the renin--angiotensin system, use of renin--angiotensin system inhibitors and the risk of myocardial infarction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

Antihypertensive therapy, the alpha-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

Therapy: PCSK9 inhibitors for treating familial hypercholesterolaemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2015.176

31 March 2020

Identifiers

DOI

10.1038/NRNEPH.2015.176

1 reference

15 August 2017

1 reference

15 August 2017

1 reference

PMCID

4778736