Gene control of tyrosine kinase TIE2 and vascular manifestations of infections (Q36658971)

15 August 2017

Gene control of tyrosine kinase TIE2 and vascular manifestations of infections (English)

1 reference

15 August 2017

13

Kevin C Kain

1 reference

15 August 2017

19

David C Christiani

1 reference

15 August 2017

Chandra C Ghosh

1

1 reference

15 August 2017

Sascha David

2

1 reference

15 August 2017

Ruyang Zhang

3

1 reference

15 August 2017

Anthony Berghelli

4

1 reference

15 August 2017

Katelyn Milam

5

1 reference

15 August 2017

Sarah J Higgins

6

1 reference

15 August 2017

Jon Hunter

7

1 reference

15 August 2017

Aditi Mukherjee

8

1 reference

15 August 2017

Yongyue Wei

9

1 reference

15 August 2017

Mei Tran

10

1 reference

15 August 2017

Freeman Suber

11

1 reference

15 August 2017

Lester Kobzik

12

1 reference

15 August 2017

Shulin Lu

14

1 reference

15 August 2017

Ansgar Santel

15

1 reference

15 August 2017

Kiichiro Yano

16

1 reference

15 August 2017

Prajna Guha

17

1 reference

15 August 2017

Daniel J Dumont

18

1 reference

15 August 2017

Samir M Parikh

20

1 reference

15 August 2017

language of work or name

English

0 references

publication date

16 February 2016

1 reference

15 August 2017

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

15 August 2017

113

1 reference

15 August 2017

9

1 reference

15 August 2017

2472-2477

1 reference

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4780619/fullTextXML

inferred from PubMed Central ID database lookup

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Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance

30 September 2017

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Platelet count mediates the contribution of a genetic variant in LRRC16A to ARDS risk

30 September 2017

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Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin

30 September 2017

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Transcriptome and genome sequencing uncovers functional variation in humans

30 September 2017

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Why activated protein C was not successful in severe sepsis and septic shock: are we still tilting at windmills?

30 September 2017

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Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis

30 September 2017

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Dysregulation of the angiopoietin-Tie-2 axis in sepsis and ARDS.

30 September 2017

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Systemic release of high mobility group box 1 (HMGB1) protein is associated with severe and fatal Plasmodium falciparum malaria

30 September 2017

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Angiopoietin-2 may contribute to multiple organ dysfunction and death in sepsis*

30 September 2017

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VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.

30 September 2017

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Impaired function of the Tie-2 receptor contributes to vascular leakage and lethality in anthrax

30 September 2017

1 reference

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Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling

30 September 2017

1 reference

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Vascular endothelial hyperpermeability induces the clinical symptoms of Clarkson disease (the systemic capillary leak syndrome).

30 September 2017

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Angiopoietin-1 requires IQ domain GTPase-activating protein 1 to activate Rac1 and promote endothelial barrier defense

30 September 2017

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Angiopoietin-1 is essential in mouse vasculature during development and in response to injury

30 September 2017

1 reference

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MARCO regulates early inflammatory responses against influenza: a useful macrophage function with adverse outcome

30 September 2017

1 reference

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Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality

30 September 2017

1 reference

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Data quality control in genetic case-control association studies.

30 September 2017

1 reference

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Transcriptome genetics using second generation sequencing in a Caucasian population

30 September 2017

1 reference

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VE-PTP controls blood vessel development by balancing Tie-2 activity

30 September 2017

1 reference

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Angiopoietin 2 is a partial agonist/antagonist of Tie2 signaling in the endothelium

30 September 2017

1 reference

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Immunodesign of experimental sepsis by cecal ligation and puncture

30 September 2017

1 reference

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Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell-cell and cell-matrix contacts

30 September 2017

1 reference

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Hantaviruses direct endothelial cell permeability by sensitizing cells to the vascular permeability factor VEGF, while angiopoietin 1 and sphingosine 1-phosphate inhibit hantavirus-directed permeability

30 September 2017

1 reference

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Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo

30 September 2017

1 reference

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Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death

30 September 2017

1 reference

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A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium

30 September 2017

1 reference

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Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

30 September 2017

1 reference

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Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1.

30 September 2017

1 reference

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Studies on inflammation. 1. The effect of histamine and serotonin on vascular permeability: an electron microscopic study

30 September 2017

1 reference

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Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells

30 September 2017

1 reference

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Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network

30 September 2017

1 reference

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Angiopoietin-1 protects the adult vasculature against plasma leakage.

30 September 2017

1 reference

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Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

30 September 2017

1 reference

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Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Octamer-dependent in vivo expression of the endothelial cell-specific TIE2 gene

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Lung-targeted RNA interference against angiopoietin-2 ameliorates multiple organ dysfunction and death in sepsis.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

The flow dependency of Tie2 expression in endotoxemia.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Broken barriers: a new take on sepsis pathogenesis.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Priming with angiopoietin-1 augments the vasculogenic potential of the peripheral blood stem cells mobilized with granulocyte colony-stimulating factor through a novel Tie2/Ets-1 pathway.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

The angiopietin-1-Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Angiopoietin-1 promotes cardiac and skeletal myocyte survival through integrins

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

The Tie-2 ligand angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Protective role of angiopoietin-1 in endotoxic shock.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Direct cell adhesion to the angiopoietins mediated by integrins

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4780619

Role of the Ets transcription factors in the regulation of the vascular-specific Tie2 gene

20 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26884170

12 December 2020

inferred from PubMed ID database lookup

Severe sepsis and septic shock

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26884170

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1519467113

1 reference

15 August 2017

0 references

1 reference

15 August 2017

1 reference