Diversity of LEF/TCF action in development and disease (Q36672669)

15 August 2017

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title

Diversity of LEF/TCF action in development and disease (English)

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15 August 2017

Arce L

1

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15 August 2017

Yokoyama NN

series ordinal

2

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15 August 2017

Waterman ML

series ordinal

3

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15 August 2017

language of work or name

English

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publication date

1 December 2006

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15 August 2017

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15 August 2017

25

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15 August 2017

57

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15 August 2017

7492-7504

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210056

15 August 2017

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cites work

A direct beta-catenin-independent interaction between androgen receptor and T cell factor 4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

A new beta-catenin-dependent activation domain in T cell factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Developmental activation of the TCR alpha enhancer requires functional collaboration among proteins bound inside and outside the core enhancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Functional interaction of beta-catenin with the transcription factor LEF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Cdx1 autoregulation is governed by a novel Cdx1-LEF1 transcription complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Alx4 binding to LEF-1 regulates N-CAM promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

All Tcf HMG box transcription factors interact with Groucho-related co-repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Drosophila Tcf and Groucho interact to repress Wingless signalling activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

TGF-beta induces novel Lef-1 splice variants through a Smad-independent signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The human candidate tumor suppressor gene HIC1 recruits CtBP through a degenerate GLDLSKK motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Two tcf3 genes cooperate to pattern the zebrafish brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

A transgenic Lef1/beta-catenin-dependent reporter is expressed in spatially restricted domains throughout zebrafish development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Ets gene PEA3 cooperates with beta-catenin-Lef-1 and c-Jun in regulation of osteopontin transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

C-terminal-binding protein directly activates and represses Wnt transcriptional targets in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Acetylation regulates subcellular localization of the Wnt signaling nuclear effector POP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

HIC-5 is a novel repressor of lymphoid enhancer factor/T-cell factor-driven transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

DNA-binding properties of the HMG domain of the lymphoid-specific transcriptional regulator LEF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Tcf4 can specifically recognize beta-catenin using alternative conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Crystal structure of a beta-catenin/Tcf complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

HMG domain proteins: architectural elements in the assembly of nucleoprotein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The APC tumor suppressor binds to C-terminal binding protein to divert nuclear beta-catenin from TCF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

A second protein kinase CK1-mediated step negatively regulates Wnt signalling by disrupting the lymphocyte enhancer factor-1/beta-catenin complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The involvement of Frodo in TCF-dependent signaling and neural tissue development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

T-cell factors: turn-ons and turn-offs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Smad4 and β-Catenin Co-activators Functionally Interact with Lymphoid-enhancing Factor to Regulate Graded Expression of Msx2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Nrarp functions to modulate neural-crest-cell differentiation by regulating LEF1 protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Links between signal transduction, transcription and adhesion in epithelial bud development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Autoregulation of canonical Wnt signaling controls midbrain development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

I-mfa domain proteins interact with Axin and affect its regulation of the Wnt and c-Jun N-terminal kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Wnt activation and alternative promoter repression of LEF1 in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Distinct roles for Xenopus Tcf/Lef genes in mediating specific responses to Wnt/beta-catenin signalling in mesoderm development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Phosphorylation by the beta-catenin/MAPK complex promotes 14-3-3-mediated nuclear export of TCF/POP-1 in signal-responsive cells in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Structural basis for DNA bending by the architectural transcription factor LEF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The Wnt effector POP-1 and the PAL-1/Caudal homeoprotein collaborate with SKN-1 to activate C. elegans endoderm development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Tcf3 and Lef1 regulate lineage differentiation of multipotent stem cells in skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Tcf3: a transcriptional regulator of axis induction in the early embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The transcriptional factor Tcf-4 contains different binding sites for beta-catenin and plakoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Interaction between Wnt and TGF-beta signalling pathways during formation of Spemann's organizer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG box

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

ovo/svb integrates Wingless and DER pathways to control epidermis differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Differential importin-alpha recognition and nuclear transport by nuclear localization signals within the high-mobility-group DNA binding domains of lymphoid enhancer factor 1 and T-cell factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Identification of two regulatory elements within the high mobility group box transcription factor XTCF-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Lef-1 and Tcf-3 transcription factors mediate tissue-specific Wnt signaling during Xenopus development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Melanocyte-specific microphthalmia-associated transcription factor isoform activates its own gene promoter through physical interaction with lymphoid-enhancing factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

C. elegans TCF protein, POP-1, converts from repressor to activator as a result of Wnt-induced lowering of nuclear levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

XIC is required for Siamois activity and dorsoanterior development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Inhibition of Tcf3 binding by I-mfa domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

The catenin p120ctn inhibits Kaiso-mediated transcriptional repression of the beta-catenin/TCF target gene matrilysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Maternal XTcf1 and XTcf4 have distinct roles in regulating Wnt target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Human sebaceous tumors harbor inactivating mutations in LEF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

PITX2, beta-catenin and LEF-1 interact to synergistically regulate the LEF-1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

TCF transcription factors, mediators of Wnt-signaling in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

A role for Kaiso-p120ctn complexes in cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Lymphoid enhancer factor/T cell factor expression in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Wnt signaling: is the party in the nucleus?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Sumoylation is involved in beta-catenin-dependent activation of Tcf-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

An HMG-box-containing T-cell factor required for thymocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

Functional diversity of Xenopus lymphoid enhancer factor/T-cell factor transcription factors relies on combinations of activating and repressing elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

7 January 2021

Integration of multiple signal transducing pathways on Fgf response elements of the Xenopus caudal homologue Xcad3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

7 January 2021

Redundant functions of TCF-1 and LEF-1 during T and NK cell development, but unique role of TCF-1 for Ly49 NK cell receptor acquisition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

7 January 2021

Smad1, beta-catenin and Tcf4 associate in a molecular complex with the Myc promoter in dysplastic renal tissue and cooperate to control Myc transcription.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

7 January 2021

Expression pattern of zebrafish tcf7 suggests unexplored domains of Wnt/beta-catenin activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210056

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210056

1 reference

15 August 2017

1 reference