Wnt signaling and gastrointestinal tumorigenesis in mouse models (Q36672676)

15 August 2017

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title

Wnt signaling and gastrointestinal tumorigenesis in mouse models (English)

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15 August 2017

Taketo MM

1

1 reference

PubMed ID

17143296

15 August 2017

language of work or name

English

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publication date

1 December 2006

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15 August 2017

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15 August 2017

25

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15 August 2017

57

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15 August 2017

7522-7530

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210058

15 August 2017

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cites work

Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

EphB receptor activity suppresses colorectal cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Stabilization of beta-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Identification and characterization of the familial adenomatous polyposis coli gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

The Wnt/beta-catenin signaling pathway targets PPARgamma activity in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Suppression of intestinal neoplasia by DNA hypomethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Hath1, down-regulated in colon adenocarcinomas, inhibits proliferation and tumorigenesis of colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.

21 January 2018

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A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Suppression of tumorigenesis and activation of Wnt signaling by bone morphogenetic protein 4 in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Hyperplastic gastric tumors with spasmolytic polypeptide-expressing metaplasia caused by tumor necrosis factor-alpha-dependent inflammation in cyclooxygenase-2/microsomal prostaglandin E synthase-1 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

COX selectivity and animal models for colon cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Foxl1 is a mesenchymal Modifier of Min in carcinogenesis of stomach and colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

The oncogenic activation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

PPARdelta status and mismatch repair mediated neoplasia in the mouse intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Cyclin D1 is not an immediate target of beta-catenin following Apc loss in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Functional consequences of DNA mismatch repair missense mutations in murine models and their impact on cancer predisposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Cyclooxygenase-2 expression in Helicobacter pylori-associated premalignant and malignant gastric lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

21 January 2018

Focus on gastric cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Colorectal cancer in mice genetically deficient in the mucin Muc2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Deficiency of Mbd2 suppresses intestinal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

Enhanced tumor formation in mice heterozygous for Blm mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

inferred from DOI database lookup

7 January 2021

based on heuristic

Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

inferred from DOI database lookup

7 January 2021

based on heuristic

E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210058

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1210058

1 reference

15 August 2017

1 reference

PubMed ID

17143296