Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice (Q34277732)

1 August 2017

Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice (English)

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1 August 2017

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Koji Aoki

1

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1 August 2017

Yoshitaka Tamai

2

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1 August 2017

Shigeo Horiike

3

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1 August 2017

Masanobu Oshima

4

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1 August 2017

Makoto M Taketo

5

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1 August 2017

language of work or name

English

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publication date

16 November 2003

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1 August 2017

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1 August 2017

35

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1 August 2017

323-330

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1 August 2017

4

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https://scigraph.springernature.com/pub.10.1038/ng1265

1 August 2017

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When checkpoints fail

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Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

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Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

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DLD-1 and HCT-15 cell lines derived separately from colorectal carcinomas have totally different chromosome changes but the same genetic origin

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Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria

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Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo

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Identifiers

DOI

10.1038/NG1265

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1 August 2017

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