Regulations and roles of the interleukin-1 receptor associated kinases (IRAKs) in innate and adaptive immunity (Q36685571)

15 August 2017

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title

Regulations and roles of the interleukin-1 receptor associated kinases (IRAKs) in innate and adaptive immunity (English)

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15 August 2017

Liwu Li

2

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author name string

Lu Gan

series ordinal

1

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15 August 2017

1 January 2006

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15 August 2017

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15 August 2017

35

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15 August 2017

3

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15 August 2017

295-302

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https://scigraph.springernature.com/pub.10.1385/ir:35:3:295

15 August 2017

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cites work

IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation

1 reference

12 December 2020

A novel splice variant of interleukin-1 receptor (IL-1R)-associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling.

1 reference

12 December 2020

IRAK-M is a negative regulator of Toll-like receptor signaling

1 reference

12 December 2020

Differential regulation of interleukin-1 receptor associated kinase 1 (IRAK1) splice variants

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12 December 2020

IL-1 receptor-associated kinase 1 regulates susceptibility to organ-specific autoimmunity

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12 December 2020

Divergence of apoptosis-inducing and preventing signals in bacteria-faced macrophages through myeloid differentiation factor 88 and IL-1 receptor-associated kinase members

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12 December 2020

Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase

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12 December 2020

A Critical Role for the Innate Immune Signaling Molecule IRAK-4 in T Cell Activation

1 reference

12 December 2020

Variant IRAK-1 haplotype is associated with increased nuclear factor-kappaB activation and worse outcomes in sepsis

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12 December 2020

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction

1 reference

12 December 2020

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

1 reference

12 December 2020

Interactions of sequence variants in interleukin-1 receptor-associated kinase4 and the toll-like receptor 6-1-10 gene cluster increase prostate cancer risk

1 reference

12 December 2020

CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells

1 reference

12 December 2020

IRAK: a kinase associated with the interleukin-1 receptor

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12 December 2020

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

1 reference

12 December 2020

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

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12 December 2020

The interleukin-1 receptor-associated kinase is degraded by proteasomes following its phosphorylation

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12 December 2020

Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells

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12 December 2020

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

1 reference

12 December 2020

Regulation of innate immunity signaling and its connection with human diseases

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12 December 2020

Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene.

1 reference

12 December 2020

Autosomal recessive Interleukin-1 receptor-associated kinase 4 deficiency in fourth-degree relatives

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12 December 2020

Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

1 reference

12 December 2020

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

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12 December 2020

Involvement of IRAK-M in peptidoglycan-induced tolerance in macrophages

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12 December 2020

Cutting edge: expression of IL-1 receptor-associated kinase-4 (IRAK-4) proteins with mutations identified in a patient with recurrent bacterial infections alters normal IRAK-4 interaction with components of the IL-1 receptor complex

1 reference

12 December 2020

Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling

1 reference

12 December 2020

Pyogenic bacterial infections in humans with IRAK-4 deficiency

1 reference

12 December 2020

IRAK1 serves as a novel regulator essential for lipopolysaccharide-induced interleukin-10 gene expression

1 reference

12 December 2020

The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory

1 reference

12 December 2020

Rapid up-regulation of IRAK-M expression following a second endotoxin challenge in human monocytes and in monocytes isolated from septic patients

1 reference

12 December 2020

IRAK1b, a novel alternative splice variant of interleukin-1 receptor-associated kinase (IRAK), mediates interleukin-1 signaling and has prolonged stability

1 reference

12 December 2020

Identifiers

DOI

10.1385/IR:35:3:295

1 reference

PubMed ID

17172653

Dimensions Publication ID

15 August 2017

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1 reference

PubMed ID

17172653