Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis. (Q36693487)

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3 January 2020

title

Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis (English)

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3 January 2020

3

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David Mangelsdorf

9

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3 January 2020

author name string

Youn-Kyoung Lee

1

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3 January 2020

Daniel R Schmidt

2

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3 January 2020

Mihwa Choi

4

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3 January 2020

Li Peng

5

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3 January 2020

Yuan Zhang

6

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3 January 2020

Bryan Goodwin

7

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3 January 2020

Robert E Hammer

8

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3 January 2020

Steven A Kliewer

10

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publication date

6 March 2008

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3 January 2020

published in

Molecular Endocrinology

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3 January 2020

volume

22

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issue

6

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3 January 2020

page(s)

1345-1356

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Compromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1.

3 January 2020

cites work

1 reference

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Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP

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Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.

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Regulation of complement C3 expression by the bile acid receptor FXR.

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Synergy between LRH-1 and beta-catenin induces G1 cyclin-mediated cell proliferation

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LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis

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The orphan nuclear receptor LRH-1 activates the ABCG5/ABCG8 intergenic promoter

30 September 2017

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The fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 element

30 September 2017

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The enzymes, regulation, and genetics of bile acid synthesis

30 September 2017

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Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter

30 September 2017

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Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I.

30 September 2017

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Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

30 September 2017

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Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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The alpha1-fetoprotein locus is activated by a nuclear receptor of the Drosophila FTZ-F1 family

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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28 June 2018

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28 June 2018

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LXRs regulate the balance between fat storage and oxidation.

5 September 2018

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The role of alpha1-fetoprotein transcription factor/LRH-1 in bile acid biosynthesis: a known nuclear receptor activator that can act as a suppressor of bile acid biosynthesis

5 September 2018

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Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha

5 September 2018

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Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine.

5 September 2018

1 reference

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Redundant pathways for negative feedback regulation of bile acid production

5 September 2018

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The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by

5 September 2018

1 reference

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Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

5 September 2018

1 reference

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Widespread recombinase expression using FLPeR (flipper) mice

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18323469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of hepatic 7 alpha-hydroxylase expression and response to dietary cholesterol in the rat and hamster

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18323469

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1210/ME.2007-0565

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18323469%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18323469%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

PubMed publication ID

18323469

1 reference