The role of PDGF in radiation oncology (Q36705396)

15 August 2017

2 references

7 April 2021

13 January 2024

The role of PDGF in radiation oncology (English)

1 reference

platelet-derived growth factor complex

15 August 2017

2 references

7 April 2021

13 January 2024

1 reference

20 November 2019

1 reference

27 November 2019

1 reference

8 February 2021

1 reference

7 April 2021

1 reference

3

Claus Belka

1 reference

15 August 2017

Minglun Li

1

1 reference

15 August 2017

Verena Jendrossek

series ordinal

2

1 reference

15 August 2017

language of work or name

1 reference

11 January 2007

8 references

15 August 2017

3 April 2019

19 June 2019

20 November 2019

27 November 2019

8 February 2021

7 April 2021

13 January 2024

8 references

15 August 2017

3 April 2019

19 June 2019

20 November 2019

27 November 2019

8 February 2021

7 April 2021

13 January 2024

2

1 reference

15 August 2017

5

1 reference

Creative Commons Attribution 2.0 Generic

15 August 2017

7 references

3 April 2019

19 June 2019

20 November 2019

27 November 2019

8 February 2021

7 April 2021

on focus list of Wikimedia project

13 January 2024

copyright status

copyrighted

0 references

ScienceSource

0 references

exact match

https://scigraph.springernature.com/pub.10.1186/1748-717x-2-5

0 references

cites work

Sunitinib in patients with metastatic renal cell carcinoma

1 reference

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Clinical and molecular studies of the effect of imatinib on advanced aggressive fibromatosis (desmoid tumor).

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Preclinical and clinical development of the oral multikinase inhibitor sorafenib in cancer treatment

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Platelet-derived growth factor (PDGF) and glial tumorigenesis

30 September 2017

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Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis.

30 September 2017

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Imatinib mesylate inhibits Leydig cell tumor growth: evidence for in vitro and in vivo activity.

30 September 2017

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Imatinib mesylate radiosensitizes human glioblastoma cells through inhibition of platelet-derived growth factor receptor.

30 September 2017

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Pulmonary complications of radiation therapy

30 September 2017

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Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors

30 September 2017

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Transgenic overexpression of platelet-derived growth factor-C in the mouse heart induces cardiac fibrosis, hypertrophy, and dilated cardiomyopathy

30 September 2017

1 reference

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Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

30 September 2017

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PDGFRA activating mutations in gastrointestinal stromal tumors.

30 September 2017

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Clinical translation of angiogenesis inhibitors

30 September 2017

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Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy

30 September 2017

1 reference

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Mesenchymal-epithelial interactions in lung development and repair: are modeling and remodeling the same process?

30 September 2017

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30 September 2017

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PDGF-D is a specific, protease-activated ligand for the PDGF beta-receptor

30 September 2017

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Normal tissue radiobiology: from the laboratory to the clinic.

30 September 2017

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Angiogenesis in cancer and other diseases

30 September 2017

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PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor

30 September 2017

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A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis

30 September 2017

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Mechanism of action and in vivo role of platelet-derived growth factor

30 September 2017

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Myofibroblasts. I. Paracrine cells important in health and disease

30 September 2017

1 reference

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Specific inhibitors of platelet-derived growth factor or epidermal growth factor receptor tyrosine kinase reduce pulmonary fibrosis in rats

30 September 2017

1 reference

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Emphysematous lesions, inflammation, and fibrosis in the lungs of transgenic mice overexpressing platelet-derived growth factor

30 September 2017

1 reference

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Growth factors secreted by bronchial epithelial cells control myofibroblast proliferation: an in vitro co-culture model of airway remodeling in asthma

30 September 2017

1 reference

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Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

30 September 2017

1 reference

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Chrysotile asbestos upregulates gene expression and production of alpha-receptors for platelet-derived growth factor (PDGF-AA) on rat lung fibroblasts

30 September 2017

1 reference

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How receptor tyrosine kinases activate Ras.

30 September 2017

1 reference

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

30 September 2017

1 reference

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A histologically distinctive interstitial pneumonia induced by overexpression of the interleukin 6, transforming growth factor beta 1, or platelet-derived growth factor B gene

30 September 2017

1 reference

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Interleukin 1 beta (IL-1 beta) and the IL-1 beta-alpha 2-macroglobulin complex upregulate the platelet-derived growth factor alpha-receptor on rat pulmonary fibroblasts

30 September 2017

1 reference

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A platelet-dependent serum factor that stimulates the proliferation of arterial smooth muscle cells in vitro

30 September 2017

1 reference

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Induction of fibronectin gene transcription and mRNA is a primary response to growth-factor stimulation of AKR-2B cells

30 September 2017

1 reference

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Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization

30 September 2017

1 reference

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Two different subunits associate to create isoform-specific platelet-derived growth factor receptors

30 September 2017

1 reference

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Isoform-specific induction of actin reorganization by platelet-derived growth factor suggests that the functionally active receptor is a dimer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Platelet-derived growth factor in idiopathic pulmonary fibrosis

30 September 2017

1 reference

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Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes

30 September 2017

1 reference

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Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Platelet-derived growth factor: purification and partial characterization

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Purification of human platelet-derived growth factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

SU5416 and SU6668 attenuate the angiogenic effects of radiation-induced tumor cell growth factor production and amplify the direct anti-endothelial action of radiation in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Platelet-derived growth factor (PDGF) autocrine signaling regulates survival and mitogenic pathways in glioblastoma cells: evidence that the novel PDGF-C and PDGF-D ligands may play a role in the development of brain tumors.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Pirfenidone inhibits PDGF isoforms in bleomycin hamster model of lung fibrosis at the translational level.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Beneficial effects of a novel inhibitor of platelet-derived growth factor receptor autophosphorylation in the rat with mesangial proliferative glomerulonephritis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Simultaneous induction of stimulatory and inhibitory signals by PDGF.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Inhibitory effect of trapidil on human meningioma cell proliferation via interruption of autocrine growth stimulation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Polarized secretion of a platelet-derived growth factor-like chemotactic factor by endothelial cells in vitro

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Effect of growth factors on hyaluronan synthesis in cultured human fibroblasts

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Autocrine control of human meningioma proliferation: secretion of platelet-derived growth-factor-like molecules

28 June 2018

1 reference

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Ligand-induced interaction between alpha- and beta-type platelet-derived growth factor (PDGF) receptors: role of receptor heterodimers in kinase activation

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

A functional soluble extracellular region of the platelet-derived growth factor (PDGF) beta-receptor antagonizes PDGF-stimulated responses

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Platelet-Derived Growth Factor is AngiogenicIn Vivo

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Small molecule receptor tyrosine kinase inhibitor of platelet-derived growth factor signaling (SU9518) modifies radiation response in fibroblasts and endothelial cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Pathological complete response in advanced gastrointestinal stromal tumor after imatinib therapy.

5 September 2018

1 reference

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Computed tomography monitoring of radiation-induced lung fibrosis in mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Long-term survival benefit and improved complete cytogenetic and molecular response rates with imatinib mesylate in Philadelphia chromosome-positive chronic-phase chronic myeloid leukemia after failure of interferon-alpha

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Target cells in radiation pneumopathy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Dexamethasone treatment does not inhibit fibroproliferation in chronic lung disease of prematurity.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Increased Binding and Chemotactic Capacities of PDGF-BB on Fibroblasts in Radiation Pneumonitis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Chronic allograft nephropathy is prevented by inhibition of platelet-derived growth factor receptor: tyrosine kinase inhibitors as a potential therapy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Attenuation of lung inflammation and fibrosis in interferon-gamma-deficient mice after intratracheal bleomycin

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Final report of the 70.2-Gy and 75.6-Gy dose levels of a phase I dose escalation study using three-dimensional conformal radiotherapy in the treatment of inoperable non-small cell lung cancer

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Platelet-derived growth factor ligand and receptor expression in response to altered blood flow in vivo.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Impact of stromal sensitivity on radiation response of tumors.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Final toxicity results of a radiation-dose escalation study in patients with non–small-cell lung cancer (NSCLC): Predictors for radiation pneumonitis and fibrosis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1780053

Pirfenidone in idiopathic pulmonary fibrosis

4 December 2018

1 reference

12 December 2020

Prospective evaluation of early lung toxicity following three-dimensional conformal radiation therapy in non-small-cell lung cancer: preliminary results

1 reference

12 December 2020

Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF

1 reference

12 December 2020

Effects of platelet-derived growth factor and transforming growth factor-beta 1 on the synthesis of a large versican-like chondroitin sulfate proteoglycan by arterial smooth muscle cells

1 reference

12 December 2020

Irradiation-induced pneumonitis mediated by the CD95/CD95-ligand system

1 reference

12 December 2020

Idiopathic pulmonary fibrosis: the inflammation hypothesis revisited

1 reference

12 December 2020

Modulation of PDGF-C and PDGF-D expression during bleomycin-induced lung fibrosis

1 reference

12 December 2020

A platelet factor stimulating human normal glial cells

1 reference

12 December 2020

Effect of platelet-derived growth factor on DNA and protein synthesis in cultured rat calvaria

1 reference

12 December 2020

Early Structural Changes in Sheep Lung Following Thoracic Irradiation

1 reference

12 December 2020

Cytokine cascades in late normal tissue radiation responses

1 reference

12 December 2020

A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis

1 reference

12 December 2020

Early and persistent alterations in the expression of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor alpha mRNA levels in fibrosis-resistant and sensitive mice after thoracic irradiation

1 reference

12 December 2020

Alveolar macrophages stimulated with titanium dioxide, chrysotile asbestos, and residual oil fly ash upregulate the PDGF receptor-alpha on lung fibroblasts through an IL-1beta-dependent mechanism

1 reference

12 December 2020

Rapid activation of PDGF-A and -B expression at sites of lung injury in asbestos-exposed rats

1 reference

12 December 2020

Identifiers

DOI

10.1186/1748-717X-2-5

1 reference

Dimensions Publication ID

15 August 2017

0 references

1 reference

15 August 2017

1 reference