Pharmacological profile of the 5-HT(2C) receptor agonist WAY-163909; therapeutic potential in multiple indications (Q36709588)

15 August 2017

1 reference

title

Pharmacological profile of the 5-HT(2C) receptor agonist WAY-163909; therapeutic potential in multiple indications (English)

1 reference

15 August 2017

John Dunlop

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

Karen L Marquis

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

H K Lim

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

Louis Leung

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

John Kao

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

Cynthia Cheesman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

Sharon Rosenzweig-Lipson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

publication date

1 September 2006

1 reference

17227285

CNS Neuroscience & Therapeutics

15 August 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

volume

12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

issue

3-4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

page(s)

167-177

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

A review of central 5-HT receptors and their function

14 May 2020

cites work

1 reference

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Interactions between 5-hydroxytryptamine receptor subtypes: Is a disturbed receptor balance contributing to the symptomatology of depression in humans?

21 January 2018

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Novel agonists of 5HT2C receptors. Synthesis and biological evaluation of substituted 2-(indol-1-yl)-1-methylethylamines and 2-(indeno[1,2-b]pyrrol-1-yl)-1-methylethylamines. Improved therapeutics for obsessive compulsive disorder

21 January 2018

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Combining pindolol and paroxetine in an animal model of chronic antidepressant action--can early onset of action be detected?

21 January 2018

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WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity

21 January 2018

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5-HT1C receptor activation: a key step in the initiation of migraine?

21 January 2018

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Evidence that mCPP-induced anxiety in the plus-maze is mediated by postsynaptic 5-HT2C receptors but not by sympathomimetic effects.

21 January 2018

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Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression.

21 January 2018

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Antiobesity effect of YM348, a novel 5-HT2C receptor agonist, in Zucker rats

21 January 2018

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Acceleration of onset of action in schedule-induced polydipsia: combinations of SSRI and 5-HT1A and 5-HT1B receptor antagonists

21 January 2018

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The olfactory bulbectomized rat as a model of depression: an update

21 January 2018

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Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptors

21 January 2018

1 reference

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Potencies of antagonists indicate that 5-HT1C receptors mediate 1-3(chlorophenyl)piperazine-induced hypophagia

21 January 2018

1 reference

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Pharmacological profile of YM348, a novel, potent and orally active 5-HT2C receptor agonist

21 January 2018

1 reference

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Desmethylimipramine (DMI) counteracts learned helplessness in rats

21 January 2018

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5-HT2C receptors mediate penile erections in rats: actions of novel and selective agonists and antagonists

21 January 2018

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Animal models of depressive illness: the importance of chronic drug treatment

21 January 2018

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Antiobesity-like effects of the 5-HT2C receptor agonist WAY-161503.

21 January 2018

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Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor

21 January 2018

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Chlorophenylpiperazine: a central serotonin agonist causing powerful anorexia in rats

21 January 2018

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Choroid plexus epithelial cells in primary culture: a model of 5HT1C receptor activation by hallucinogenic drugs

21 January 2018

1 reference

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5-HT2C receptor activation decreases appetite and body weight in obese subjects

21 January 2018

1 reference

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Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors

21 January 2018

1 reference

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Comparative effects of continuous infusion of mCPP, Ro 60-0175 and d-fenfluramine on food intake, water intake, body weight and locomotor activity in rats.

21 January 2018

1 reference

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m-Chlorophenylpiperazine decreases food intake in a test meal

21 January 2018

1 reference

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Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder

21 January 2018

1 reference

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Synthesis and 5-hydroxytryptamine (5-HT) activity of 2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5-(6H)ones and 2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoxalines

21 January 2018

1 reference

12 December 2020

Oral administration of the 5-HT2Creceptor agonist, mCPP, reduces body weight gain in rats over 28 days as a result of maintained hypophagia.

1 reference

12 December 2020

WAY-163909 [(7bR,10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole]: A novel 5-hydroxytryptamine 2C receptor-selective agonist with preclinical antipsychotic-like activity

1 reference

12 December 2020

Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants

1 reference

12 December 2020

10.1111/J.1527-3458.2006.00167.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6506193&resulttype=core&format=json

14 May 2020

17227285

1 reference