Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter. (Q36710904)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18332107%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter (English)

1 reference

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4 January 2020

0 references

7

1 reference

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4 January 2020

Wei-Guo Zhu

15

1 reference

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4 January 2020

author name string

Li-Peng Wu

1

1 reference

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4 January 2020

Xi Wang

2

1 reference

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4 January 2020

Lian Li

3

1 reference

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4 January 2020

Ying Zhao

4

1 reference

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4 January 2020

Shaoli Lu

5

1 reference

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4 January 2020

Yu Yu

6

1 reference

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4 January 2020

Xiangyu Liu

8

1 reference

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4 January 2020

Jing Yang

9

1 reference

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4 January 2020

Zhixin Zheng

10

1 reference

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4 January 2020

Hui Zhang

11

1 reference

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4 January 2020

Jingnan Feng

12

1 reference

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4 January 2020

Yang Yang

13

1 reference

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4 January 2020

Haiying Wang

14

1 reference

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4 January 2020

language of work or name

English

0 references

publication date

10 March 2008

1 reference

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Molecular and Cellular Biology

4 January 2020

published in

1 reference

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4 January 2020

volume

28

1 reference

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4 January 2020

issue

10

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4 January 2020

page(s)

3219-3235

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UHRF1 plays a role in maintaining DNA methylation in mammalian cells

4 January 2020

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Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication

30 September 2017

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Active cytosine demethylation triggered by a nuclear receptor involves DNA strand breaks.

30 September 2017

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5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation

30 September 2017

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Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin

30 September 2017

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Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1).

30 September 2017

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Functions of histone-modifying enzymes in development

30 September 2017

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De novo CpG island methylation in human cancer cells

30 September 2017

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G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.

30 September 2017

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The Polycomb group protein EZH2 directly controls DNA methylation

30 September 2017

1 reference

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The diverse functions of histone lysine methylation

30 September 2017

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DNA methylation and histone modifications: teaming up to silence genes

30 September 2017

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Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter

30 September 2017

1 reference

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Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines

30 September 2017

1 reference

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Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells

30 September 2017

1 reference

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Patupilone acts as radiosensitizing agent in multidrug-resistant cancer cells in vitro and in vivo.

30 September 2017

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Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

30 September 2017

1 reference

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Human maintenance DNA (cytosine-5)-methyltransferase and p53 modulate expression of p53-repressed promoters

30 September 2017

1 reference

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Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.

30 September 2017

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CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription

30 September 2017

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RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells

30 September 2017

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A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements

30 September 2017

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Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains

30 September 2017

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Partitioning and plasticity of repressive histone methylation states in mammalian chromatin

30 September 2017

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Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location

30 September 2017

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Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

30 September 2017

1 reference

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Histone deacetylase inhibitors activate p21(WAF1) expression via ATM.

30 September 2017

1 reference

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Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter

30 September 2017

1 reference

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Valproate induces replication-independent active DNA demethylation

30 September 2017

1 reference

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The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

30 September 2017

1 reference

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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

30 September 2017

1 reference

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DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

30 September 2017

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Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer.

30 September 2017

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Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure

30 September 2017

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Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases

30 September 2017

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G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

30 September 2017

1 reference

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DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

30 September 2017

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Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase

30 September 2017

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Histone modifications in transcriptional regulation

30 September 2017

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30 September 2017

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Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

30 September 2017

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Rb targets histone H3 methylation and HP1 to promoters

30 September 2017

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Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3

30 September 2017

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Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

30 September 2017

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Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

30 September 2017

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Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family

30 September 2017

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Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation

30 September 2017

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Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31

30 September 2017

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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

30 September 2017

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Trichostatin A causes selective loss of DNA methylation in Neurospora

30 September 2017

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Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

30 September 2017

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

30 September 2017

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De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase

30 September 2017

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Specific targeting and killing activities of anti-P-glycoprotein monoclonal antibody MRK16 directed against intrinsically multidrug-resistant human colorectal carcinoma cell lines in the nude mouse model

30 September 2017

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Cellular and viral DNA hypomethylation associated with induction of Epstein-Barr virus lytic cycle

30 September 2017

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A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

30 September 2017

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A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

30 September 2017

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Histone deacetylase inhibitor apicidin-mediated drug resistance: involvement of P-glycoprotein

28 June 2018

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Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation

5 September 2018

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Novel mechanisms of apoptosis induced by histone deacetylase inhibitors.

5 September 2018

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Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.

5 September 2018

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Dependence of histone modifications and gene expression on DNA hypermethylation in cancer.

5 September 2018

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Cell division is required for de novo methylation of CpG islands in bladder cancer cells

5 September 2018

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Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells

5 September 2018

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DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors.

5 September 2018

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Allele-specific histone acetylation accompanies genomic imprinting of the insulin-like growth factor II receptor gene

5 September 2018

1 reference

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Reversal of multidrug resistance by transduction of cytokine genes into human colon carcinoma cells

5 September 2018

1 reference

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Down-regulation of human DNA-(cytosine-5) methyltransferase induces cell cycle regulators p16(ink4A) and p21(WAF/Cip1) by distinct mechanisms

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18332107

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.01516-07

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18332107%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18332107%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference