Viral vector-mediated and cell-based therapies for treatment of cystic fibrosis (Q36712185)

15 August 2017

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title

Viral vector-mediated and cell-based therapies for treatment of cystic fibrosis (English)

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15 August 2017

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Paul B McCray

4

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author name string

Terence R Flotte

1

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15 August 2017

Philip Ng

2

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15 August 2017

Doug E Dylla

3

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15 August 2017

Guoshun Wang

5

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15 August 2017

Jay K Kolls

6

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15 August 2017

Jim Hu

7

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15 August 2017

1 February 2007

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15 August 2017

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15 August 2017

15

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15 August 2017

2

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15 August 2017

229-241

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Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

15 August 2017

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Identification of the cystic fibrosis gene: chromosome walking and jumping

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Physiological basis of cystic fibrosis: a historical perspective

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Submucosal glands are the predominant site of CFTR expression in the human bronchus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Advances in cystic fibrosis gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Adenoviral vectors for gene replacement therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Gene therapy progress and prospects: adenoviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

The impact of adenovirus infection on the immunocompromised host

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Improvements in adenoviral vector technology: overcoming barriers for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. I. Methods, safety, and clinical implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Aerosol and lobar administration of a recombinant adenovirus to individuals with cystic fibrosis. II. Transfection efficiency in airway epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Retargeting the coxsackievirus and adenovirus receptor to the apical surface of polarized epithelial cells reveals the glycocalyx as a barrier to adenovirus-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Delivery of an adenovirus vector in a calcium phosphate coprecipitate enhances the therapeutic index of gene transfer to airway epithelia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

EGTA enhancement of adenovirus-mediated gene transfer to mouse tracheal epithelium in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Increasing epithelial junction permeability enhances gene transfer to airway epithelia In vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Potentiation of gene transfer to the mouse lung by complexes of adenovirus vector and polycations improves therapeutic potential

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Enhanced in vivo airway gene transfer via transient modification of host barrier properties with a surface-active agent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Safety and efficiency of modulating paracellular permeability to enhance airway epithelial gene transfer in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Aerosol delivery of an enhanced helper-dependent adenovirus formulation to rabbit lung using an intratracheal catheter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Safety of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lungs of nonhuman primates.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

In vivo evaluation of the safety of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lung.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Gene therapy via primary myoblasts: long-term expression of factor IX protein following transplantation in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: comparison of E2a wild type and E2a deleted vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Toxicological comparison of E2a-deleted and first-generation adenoviral vectors expressing alpha1-antitrypsin after systemic delivery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Cellular and humoral immune responses to viral antigens create barriers to lung-directed gene therapy with recombinant adenoviruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Prolonged transgene expression in cotton rat lung with recombinant adenoviruses defective in E2a.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Transfer of the CFTR gene to the lung of nonhuman primates with E1-deleted, E2a-defective recombinant adenoviruses: a preclinical toxicology study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Helper-dependent adenoviral vectors for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Chromosomal integration pattern of a helper-dependent minimal adenovirus vector with a selectable marker inserted into a 27.4-kilobase genomic stuffer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Reduced inflammation and improved airway expression using helper-dependent adenoviral vectors with a K18 promoter.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Targeting transgene expression to airway epithelia and submucosal glands, prominent sites of human CFTR expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Targeting transgene expression for cystic fibrosis gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Promoter attenuation in gene therapy: interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Protection of Cftr knockout mice from acute lung infection by a helper-dependent adenoviral vector expressing Cftr in airway epithelia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Improved system for helper-dependent adenoviral vector production

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Improved hepatic transduction, reduced systemic vector dissemination, and long-term transgene expression by delivering helper-dependent adenoviral vectors into the surgically isolated liver of nonhuman primates.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Cyclophosphamide diminishes inflammation and prolongs transgene expression following delivery of adenoviral vectors to mouse liver and lung.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Transient immunosuppression with deoxyspergualin improves longevity of transgene expression and ability to readminister adenoviral vector to the mouse lung

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Nondepleting anti-CD4 antibody treatment prolongs lung-directed E1-deleted adenovirus-mediated gene expression in rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

"Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

PEGylation of adenovirus with retention of infectivity and protection from neutralizing antibody in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Circumvention of anti-adenovirus neutralizing immunity by administration of an adenoviral vector of an alternate serotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

"Sero-switch" adenovirus-mediated in vivo gene transfer: circumvention of anti-adenovirus humoral immune defenses against repeat adenovirus vector administration by changing the adenovirus serotype

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Adeno-associated virus: a ubiquitous commensal of mammals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Detection of adeno-associated virus (AAV)-specific nucleotide sequences in DNA isolated from latently infected Detroit 6 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

The cryptic life style of adeno-associated virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Integration of the adeno-associated virus genome into cellular DNA in latently infected human Detroit 6 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Clades of Adeno-associated viruses are widely disseminated in human tissues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Use of adeno-associated virus as a mammalian DNA cloning vector: transduction of neomycin resistance into mammalian tissue culture cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

A Human Parvovirus, Adeno-Associated Virus, as a Eucaryotic Vector: Transient Expression and Encapsidation of the Procaryotic Gene for Chloramphenicol Acetyltransferase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Adeno-associated virus vector for high-frequency integration, expression, and rescue of genes in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Gene expression from adeno-associated virus vectors in airway epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

A phase I study of an adeno-associated virus-CFTR gene vector in adult CF patients with mild lung disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Phase I trial of intranasal and endobronchial administration of a recombinant adeno-associated virus serotype 2 (rAAV2)-CFTR vector in adult cystic fibrosis patients: a two-part clinical study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

A phase I/II study of tgAAV-CF for the treatment of chronic sinusitis in patients with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Safety and biological efficacy of an adeno-associated virus vector-cystic fibrosis transmembrane regulator (AAV-CFTR) in the cystic fibrosis maxillary sinus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

In vivo model of adeno-associated virus vector persistence and rescue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Novel transcriptional regulatory signals in the adeno-associated virus terminal repeat A/D junction element

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

A phase I study of aerosolized administration of tgAAVCF to cystic fibrosis subjects with mild lung disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis transmembrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

A phase II, double-blind, randomized, placebo-controlled clinical trial of tgAAVCF using maxillary sinus delivery in patients with cystic fibrosis with antrostomies.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Correlation between DNA transfer and cystic fibrosis airway epithelial cell correction after recombinant adeno-associated virus serotype 2 gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Polarity influences the efficiency of recombinant adenoassociated virus infection in differentiated airway epithelia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Rate limiting steps of AAV transduction and implications for human gene therapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Factors influencing adeno-associated virus-mediated gene transfer to human cystic fibrosis airway epithelial cells: comparison with adenovirus vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Second-strand genome conversion of adeno-associated virus type 2 (AAV-2) and AAV-5 is not rate limiting following apical infection of polarized human airway epithelia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Ubiquitination of both adeno-associated virus type 2 and 5 capsid proteins affects the transduction efficiency of recombinant vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Distinct classes of proteasome-modulating agents cooperatively augment recombinant adeno-associated virus type 2 and type 5-mediated transduction from the apical surfaces of human airway epithelia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Enhancing rAAV vector expression in the lung

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Intrapleural administration of a serotype 5 adeno-associated virus coding for alpha1-antitrypsin mediates persistent, high lung and serum levels of alpha1-antitrypsin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Cell proliferation in bronchial epithelium and submucosal glands of cystic fibrosis patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Organization of adeno-associated virus DNA in latently infected Detroit 6 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Site-specific integration by adeno-associated virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Mapping and direct visualization of a region-specific viral DNA integration site on chromosome 19q13-qter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Targeted integration of adeno-associated virus (AAV) into human chromosome 19

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Adeno-associated virus: integration at a specific chromosomal locus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Effect of DNA-dependent protein kinase on the molecular fate of the rAAV2 genome in skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

DNA-dependent PK inhibits adeno-associated virus DNA integration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Adeno-associated virus vectors integrate at chromosome breakage sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Systematic determination of the packaging limit of lentiviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Lentiviral vectors for gene therapy of cystic fibrosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Recovery of airway cystic fibrosis transmembrane conductance regulator function in mice with cystic fibrosis after single-dose lentivirus-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Gene transfer vectors derived from equine infectious anemia virus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Integrated self-inactivating lentiviral vectors produce full-length genomic transcripts competent for encapsidation and integration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Development of an epithelium-specific expression cassette with human DNA regulatory elements for transgene expression in lung airways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Targeting expression of a transgene to the airway surface epithelium using a ciliated cell-specific promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Pseudotyped human lentiviral vector-mediated gene transfer to airway epithelia in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Correction of the apical membrane chloride permeability defect in polarized cystic fibrosis airway epithelia following retroviral-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

1 reference

7 January 2021

Lentiviral vector gene transfer into fetal rhesus monkeys (Macaca mulatta): lung-targeting approaches

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Intrapulmonary and intramyocardial gene transfer in rhesus monkeys (Macaca mulatta): safety and efficiency of HIV-1-derived lentiviral vectors for fetal gene delivery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Human fetal trachea-SCID mouse xenografts: efficacy of vesicular stomatitis virus-G pseudotyped lentiviral-mediated gene transfer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Enhanced epithelial gene transfer by modulation of tight junctions with sodium caprate.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Filovirus-pseudotyped lentiviral vector can efficiently and stably transduce airway epithelia in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Lentivirus vectors pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independently of folate receptor alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Retrovirus vectors bearing jaagsiekte sheep retrovirus Env transduce human cells by using a new receptor localized to chromosome 3p21.3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Gene transfer to respiratory epithelia with lentivirus pseudotyped with Jaagsiekte sheep retrovirus envelope glycoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Influenza M2 envelope protein augments avian influenza hemagglutinin pseudotyping of lentiviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Viscoelastic Gel Formulations Enhance Airway Epithelial Gene Transfer with Viral Vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

HIV-1 integration in the human genome favors active genes and local hotspots

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Transcription start regions in the human genome are favored targets for MLV integration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Silencing and variegation of gammaretrovirus and lentivirus vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Controlling integration specificity of a yeast retrotransposon

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Performance- and safety-enhanced lentiviral vectors containing the human interferon-beta scaffold attachment region and the chicken beta-globin insulator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Lentiviral vector retargeting to P-glycoprotein on metastatic melanoma through intravenous injection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Targeted gene delivery by intravenous injection of retroviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Thixotropic solutions enhance viral-mediated gene transfer to airway epithelia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Derivation of type II alveolar epithelial cells from murine embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Embryonic stem cells generate airway epithelial tissue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Cytological Identification of Radiation-Chimæras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Identification of clonogenic common lymphoid progenitors in mouse bone marrow

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Somatic stem cell plasticity: current evidence and emerging concepts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Dystrophin expression in the mdx mouse restored by stem cell transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Pluripotency of mesenchymal stem cells derived from adult marrow

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Bone marrow cells regenerate infarcted myocardium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Bone marrow as a potential source of hepatic oval cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Assessment of cystic fibrosis transmembrane conductance regulator (CFTR) activity in CFTR-null mice after bone marrow transplantation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Limited restoration of cystic fibrosis lung epithelium in vivo with adult bone marrow-derived cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Failure of bone marrow to reconstitute lung epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Bone marrow-derived SP cells can contribute to the respiratory tract of mice in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Multilineage potential of adult human mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Marrow stromal cells as stem cells for nonhematopoietic tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Hepatocytes from non-hepatic adult stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Pancreatic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Gastrointestinal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Mammalian neural stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Circulating skeletal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Identification of a novel population of muscle stem cells in mice: potential for muscle regeneration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Bone marrow-derived mesenchymal stem cells in repair of the injured lung

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Viable offspring derived from fetal and adult mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Embryonic and somatic cell cloning.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Transplanted bone marrow regenerates liver by cell fusion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Stem cells. Cloning researcher says work is flawed but claims results stand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300002

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300002

1 reference

15 August 2017

1 reference