Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork (Q36724719)

15 August 2017

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title

Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork (English)

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15 August 2017

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Christian Hertweck

1

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Andreas Bechthold

series ordinal

4

object named as

Andreas Bechthold

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15 August 2017

Andriy Luzhetskyy

2

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PubMed ID

17268612

15 August 2017

Yuri Rebets

series ordinal

3

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15 August 2017

22 November 2006

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15 August 2017

Natural Product Reports

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15 August 2017

24

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15 August 2017

1

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15 August 2017

162-190

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Biosynthesis of polyketides in heterologous hosts

15 August 2017

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Genetic Contributions to Understanding Polyketide Synthases

21 January 2018

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It works: combinatorial biosynthesis for generating novel glycosylated compounds

21 January 2018

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Engineering biodiversity with type II polyketide synthase genes

21 January 2018

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Tolerance and specificity of polyketide synthases

21 January 2018

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Biosynthesis of polyketides (other than actinomycete macrolides).

21 January 2018

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Biosynthesis and attachment of novel bacterial polyketide synthase starter units

21 January 2018

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Modification of post-PKS tailoring steps through combinatorial biosynthesis

21 January 2018

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Enzymes in the biosynthesis of aromatic polyketide antibiotics

21 January 2018

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Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

21 January 2018

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Apoptosis in young rats with adriamycin-induced cardiomyopathy--comparison with pirarubicin, a new anthracycline derivative

21 January 2018

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31 P NMR study of daunorubicin-d(CGTACG) complex in solution Evidence of the intercalation sites

21 January 2018

1 reference

Role of the sugar moiety in the pharmacological activity of anthracyclines: development of a novel series of disaccharide analogs.

21 January 2018

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Mithramycin forms a stable dimeric complex by chelating with Fe(II): DNA-interacting characteristics, cellular permeation and cytotoxicity

21 January 2018

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The three-dimensional structure of the 4:1 mithramycin:d(ACCCGGGT)(2) complex: evidence for an interaction between the E saccharides

21 January 2018

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Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance

21 January 2018

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Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.

21 January 2018

1 reference

Antimicrobial activity and pharmacokinetics/pharmacodynamics of the novel glycylcycline, tigecycline

21 January 2018

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Angucycline group antibiotics

21 January 2018

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Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus

21 January 2018

1 reference

Structural investigation of the hedamycin:d(ACCGGT)2 complex by NMR and restrained molecular dynamics

21 January 2018

1 reference

Regulation of jadomycin B production in Streptomyces venezuelae ISP5230: involvement of a repressor gene, jadR2.

21 January 2018

1 reference

Jadomycin, a novel 8H-benz[b]oxazolo[3,2-f]phenanthridine antibiotic from from streptomyces venezuelae ISP5230

21 January 2018

1 reference

Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide

21 January 2018

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Biochemical characterisation of elsamicin and other coumarin-related antitumour agents as potent inhibitors of human topoisomerase II.

21 January 2018

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Effects of the antibiotic resistomycin on the synthesis of macromolecules

21 January 2018

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Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus

21 January 2018

1 reference

A mechanism of benzoic acid biosynthesis in plants and bacteria that mirrors fatty acid beta-oxidation.

21 January 2018

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Bacterial fatty acid biosynthesis: targets for antibacterial drug discovery

21 January 2018

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Bacterial fatty-acid biosynthesis: a genomics-driven target for antibacterial drug discovery

21 January 2018

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Functional angucycline-like antibiotic gene cluster in the terminal inverted repeats of the Streptomyces ambofaciens linear chromosome

21 January 2018

1 reference

Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis

21 January 2018

1 reference

Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites

21 January 2018

1 reference

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

21 January 2018

1 reference

Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase.

21 January 2018

1 reference

Cloning, nucleotide sequence, and heterologous expression of the biosynthetic gene cluster for R1128, a non-steroidal estrogen receptor antagonist. Insights into an unusual priming mechanism

21 January 2018

1 reference

The entire nogalamycin biosynthetic gene cluster of Streptomyces nogalater: characterization of a 20-kb DNA region and generation of hybrid structures

21 January 2018

1 reference

Cloning, sequencing and heterologous expression of the medermycin biosynthetic gene cluster of Streptomyces sp. AM-7161: towards comparative analysis of the benzoisochromanequinone gene clusters

21 January 2018

1 reference

The complete gene cluster of the antitumor agent gilvocarcin V and its implication for the biosynthesis of the gilvocarcins

21 January 2018

1 reference

The hedamycin locus implicates a novel aromatic PKS priming mechanism.

21 January 2018

1 reference

A gene cluster encoding resistomycin biosynthesis in Streptomyces resistomycificus; exploring polyketide cyclization beyond linear and angucyclic patterns

21 January 2018

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Biosynthesis of cervimycin C, an aromatic polyketide antibiotic bearing an unusual dimethylmalonyl moiety

21 January 2018

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Genetic organization of the biosynthetic gene cluster for the antitumor angucycline oviedomycin in Streptomyces antibioticus ATCC 11891.

21 January 2018

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Reconstitution of the iterative type II polyketide synthase for tetracenomycin F2 biosynthesis.

21 January 2018

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Type I polyketide biosynthesis in bacteria (part B).

21 January 2018

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Type I polyketide biosynthesis in bacteria (Part A--erythromycin biosynthesis).

21 January 2018

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4-[2-(2-amino-2-oxoethyl)-2,7-dihydroxy-4-oxochroman-5-yl]-3-hydroxybut-2-enoic acid

21 January 2018

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MCAT is not required for in vitro polyketide synthesis in a minimal actinorhodin polyketide synthase from Streptomyces coelicolor

21 January 2018

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Self-malonylation is an intrinsic property of a chemically synthesized type II polyketide synthase acyl carrier protein

21 January 2018

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Purification and in vitro reconstitution of the essential protein components of an aromatic polyketide synthase

21 January 2018

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Purification of a malonyltransferase from Streptomyces coelicolor A3(2) and analysis of its genetic determinant

21 January 2018

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Kinetic analysis of the actinorhodin aromatic polyketide synthase

21 January 2018

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Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase

21 January 2018

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An antibiotic factory caught in action

21 January 2018

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Crystal structure of the priming beta-ketosynthase from the R1128 polyketide biosynthetic pathway

21 January 2018

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Solution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2)

21 January 2018

1 reference

Solution structure and dynamics of oxytetracycline polyketide synthase acyl carrier protein from Streptomyces rimosus

21 January 2018

1 reference

Solution Structure and Backbone Dynamics of the Holo Form of the Frenolicin Acyl Carrier Protein,

21 January 2018

1 reference

The crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Synechocystis sp. at 1.54 A resolution and its relationship to other condensing enzymes

21 January 2018

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Structural control of polyketide formation in plant-specific polyketide synthases

21 January 2018

1 reference

Cervimycin A-D: a polyketide glycoside complex from a cave bacterium can defeat vancomycin resistance

21 January 2018

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Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes

21 January 2018

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Polyketide chain length control by chain length factor

21 January 2018

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Ectopic expression of the minimal whiE polyketide synthase generates a library of aromatic polyketides of diverse sizes and shapes

21 January 2018

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Engineered biosynthesis of aklanonic acid analogues

21 January 2018

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Biosynthetic Studies of Daunorubicin and Tetracenomycin C

21 January 2018

1 reference

Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase

21 January 2018

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Minimal Streptomyces sp. strain C5 daunorubicin polyketide biosynthesis genes required for aklanonic acid biosynthesis

21 January 2018

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Purification and properties of the Streptomyces peucetius DpsC beta-ketoacyl:acyl carrier protein synthase III that specifies the propionate-starter unit for type II polyketide biosynthesis

21 January 2018

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In vitro reconstitution and analysis of the chain initiating enzymes of the R1128 polyketide synthase

21 January 2018

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Ketosynthases in the initiation and elongation modules of aromatic polyketide synthases have orthogonal acyl carrier protein specificity

21 January 2018

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Engineered biosynthesis of regioselectively modified aromatic polyketides using bimodular polyketide synthases

21 January 2018

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Mutasynthesis of enterocin and wailupemycin analogues

21 January 2018

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Characterization of benzoyl coenzyme A biosynthesis genes in the enterocin-producing bacterium "Streptomyces maritimus"

21 January 2018

1 reference

Context-dependent behavior of the enterocin iterative polyketide synthase; a new model for ketoreduction

21 January 2018

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The crystal structure of the actIII actinorhodin polyketide reductase: proposed mechanism for ACP and polyketide binding

21 January 2018

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Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity

21 January 2018

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Iterative type II polyketide synthases, cyclases and ketoreductases exhibit context-dependent behavior in the biosynthesis of linear and angular decapolyketides

21 January 2018

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Biosynthesis of anthraquinones by interspecies cloning of actinorhodin biosynthesis genes in streptomycetes: clarification of actinorhodin gene functions

21 January 2018

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Cloning, sequencing, and analysis of aklaviketone reductase from Streptomyces sp. strain C5

21 January 2018

1 reference

Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster

21 January 2018

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Nucleotide sequence of the aknA region of the aklavinone biosynthetic gene cluster of Streptomyces galilaeus

21 January 2018

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Proof that the ACTVI genetic region of Streptomyces coelicolor A3(2) is involved in stereospecific pyran ring formation in the biosynthesis of actinorhodin

21 January 2018

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Functional complementation of pyran ring formation in actinorhodin biosynthesis in Streptomyces coelicolor A3(2) by ketoreductase genes for granaticin biosynthesis

21 January 2018

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A new mode of stereochemical control revealed by analysis of the biosynthesis of dihydrogranaticin in Streptomyces violaceoruber Tü22.

21 January 2018

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Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin

21 January 2018

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Domain analysis of the molecular recognition features of aromatic polyketide synthase subunits

21 January 2018

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Deciphering the mechanism for the assembly of aromatic polyketides by a bacterial polyketide synthase

21 January 2018

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Structure of the polyketide cyclase SnoaL reveals a novel mechanism for enzymatic aldol condensation

21 January 2018

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Production of aromatic minimal polyketides by the daunorubicin polyketide synthase genes reveals the incompatibility of the heterologous DpsY and JadI cyclases

21 January 2018

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Engineering anthracycline biosynthesis toward angucyclines

21 January 2018

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Cloning and characterization of a polyketide synthase gene from Streptomyces fradiae Tü2717, which carries the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation

21 January 2018

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Characterization of Streptomyces nogalater genes encoding enzymes involved in glycosylation steps in nogalamycin biosynthesis

21 January 2018

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A gene cluster from Streptomyces galilaeus involved in glycosylation of aclarubicin

21 January 2018

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Identification of a cyclase gene dictating the C-9 stereochemistry of anthracyclines from Streptomyces nogalater

21 January 2018

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Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity

21 January 2018

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Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus

21 January 2018

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Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase

21 January 2018

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LanV, a bifunctional enzyme: aromatase and ketoreductase during landomycin A biosynthesis

21 January 2018

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Crystal structure of aclacinomycin-10-hydroxylase, a S-adenosyl-L-methionine-dependent methyltransferase homolog involved in anthracycline biosynthesis in Streptomyces purpurascens

21 January 2018

1 reference

Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products

21 January 2018

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Crystallization and preliminary X-ray diffraction studies of aclacinomycin-10-methyl esterase and aclacinomycin-10-hydroxylase from Streptomyces purpurascens

21 January 2018

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Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycin

21 January 2018

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Generation of novel landomycins M and O through targeted gene disruption

21 January 2018

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Oxygenases without requirement for cofactors or metal ions

21 January 2018

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Organisation and functions of the actV A region of the actinorhodin biosynthetic gene cluster of Streptomyces coelicolor

21 January 2018

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Identification of a monooxygenase from Streptomyces coelicolor A3(2) involved in biosynthesis of actinorhodin: purification and characterization of the recombinant enzyme

21 January 2018

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The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis.

21 January 2018

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Cloning, sequencing, and heterologous expression of the elmGHIJ genes involved in the biosynthesis of the polyketide antibiotic elloramycin from Streptomyces olivaceus Tü2353.

21 January 2018

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Isolation and sequence analysis of polyketide synthase genes from the daunomycin-producing Streptomyces sp. strain C5.

21 January 2018

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Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin

21 January 2018

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Structures of redox enzymes

21 January 2018

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Flavoenzymes: diverse catalysts with recurrent features

21 January 2018

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EncM, a versatile enterocin biosynthetic enzyme involved in Favorskii oxidative rearrangement, aldol condensation, and heterocycle-forming reactions

21 January 2018

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Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.

21 January 2018

1 reference

Characterization of kinetics and products of the Baeyer-Villiger oxygenase MtmOIV, the key enzyme of the biosynthetic pathway toward the natural product anticancer drug mithramycin from Streptomyces argillaceus

21 January 2018

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Oxidative rearrangement processes in the biosynthesis of gilvocarcin V.

21 January 2018

1 reference

Engineering deoxysugar biosynthetic pathways from antibiotic-producing microorganisms. A tool to produce novel glycosylated bioactive compounds

21 January 2018

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Genes and enzymes involved in deoxysugar biosynthesis in bacteria

21 January 2018

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Remarkable structural similarities between diverse glycosyltransferases

21 January 2018

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Crystal structure of vancosaminyltransferase GtfD from the vancomycin biosynthetic pathway: interactions with acceptor and nucleotide ligands

21 January 2018

1 reference

Structure of the TDP-epi-vancosaminyltransferase GtfA from the chloroeremomycin biosynthetic pathway

21 January 2018

1 reference

Structure of the UDP-glucosyltransferase GtfB that modifies the heptapeptide aglycone in the biosynthesis of vancomycin group antibiotics

21 January 2018

1 reference

T4 phage beta-glucosyltransferase: substrate binding and proposed catalytic mechanism

21 January 2018

1 reference

Two sequence elements of glycosyltransferases involved in urdamycin biosynthesis are responsible for substrate specificity and enzymatic activity.

21 January 2018

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Engineered urdamycin glycosyltransferases are broadened and altered in substrate specificity

21 January 2018

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AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A.

21 January 2018

1 reference

AknK is an L-2-deoxyfucosyltransferase in the biosynthesis of the anthracycline aclacinomycin A.

21 January 2018

1 reference

Two new tailoring enzymes, a glycosyltransferase and an oxygenase, involved in biosynthesis of the angucycline antibiotic urdamycin A in Streptomyces fradiae Tü2717.

21 January 2018

1 reference

The NDP-sugar co-substrate concentration and the enzyme expression level influence the substrate specificity of glycosyltransferases: cloning and characterization of deoxysugar biosynthetic genes of the urdamycin biosynthetic gene cluster

21 January 2018

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Function of glycosyltransferase genes involved in urdamycin A biosynthesis.

21 January 2018

1 reference

Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis

21 January 2018

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LanGT2 Catalyzes the First Glycosylation Step during landomycin A biosynthesis

21 January 2018

1 reference

Elucidation of the function of two glycosyltransferase genes (lanGT1 and lanGT4) involved in landomycin biosynthesis and generation of new oligosaccharide antibiotics

21 January 2018

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Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis

21 January 2018

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Iteratively acting glycosyltransferases involved in the hexasaccharide biosynthesis of landomycin A.

21 January 2018

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Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways

21 January 2018

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Rational saccharide extension by using the natural product glycosyltransferase LanGT4.

21 January 2018

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The C-Glycosyltransferase UrdGT2 is unselective toward d- and l-configured nucleotide-bound rhodinoses

21 January 2018

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Regulation of secondary metabolism in streptomycetes

21 January 2018

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Global analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways in Streptomyces coelicolor using DNA microarrays

21 January 2018

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Genetics of differentiation in Streptomyces

21 January 2018

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Codon usage in the G+C-rich Streptomyces genome

21 January 2018

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The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces

21 January 2018

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Accumulation of bldA-specified tRNA is temporally regulated in Streptomyces coelicolor A3(2).

21 January 2018

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TTA codons in some genes prevent their expression in a class of developmental, antibiotic-negative, Streptomyces mutants

21 January 2018

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The positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus is mistranslated in a bldA mutant

21 January 2018

1 reference

Expression of the regulatory protein LndI for landomycin E production in Streptomyces globisporus 1912 is controlled by the availability of tRNA for the rare UUA codon.

21 January 2018

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sigma(BldN), an extracytoplasmic function RNA polymerase sigma factor required for aerial mycelium formation in Streptomyces coelicolor A3(2).

21 January 2018

1 reference

Study of the bldG locus suggests that an anti-anti-sigma factor and an anti-sigma factor may be involved in Streptomyces coelicolor antibiotic production and sporulation.

21 January 2018

1 reference

An oligopeptide permease responsible for the import of an extracellular signal governing aerial mycelium formation in Streptomyces coelicolor

21 January 2018

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Different alleles of the response regulator gene bldM arrest Streptomyces coelicolor development at distinct stages.

21 January 2018

1 reference

The bldC developmental locus of Streptomyces coelicolor encodes a member of a family of small DNA-binding proteins related to the DNA-binding domains of the MerR family.

21 January 2018

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The ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2) plays a conditional role in antibiotic production and morphological differentiation

21 January 2018

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Induction of ppGpp synthesis in Streptomyces coelicolor A3(2) grown under conditions of nutritional sufficiency elicits actII-ORF4 transcription and actinorhodin biosynthesis.

21 January 2018

1 reference

The A-factor regulatory cascade and cAMP in the regulation of physiological and morphological development in Streptomyces griseus

21 January 2018

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Involvement of two A-factor receptor homologues in Streptomyces coelicolor A3(2) in the regulation of secondary metabolism and morphogenesis

21 January 2018

1 reference

Purification and structural determination of SCB1, a gamma-butyrolactone that elicits antibiotic production in Streptomyces coelicolor A3(2)

21 January 2018

1 reference

Control of growth, secondary metabolism and sporulation in Streptomyces venezuelae ISP5230 by jadW(1), a member of the afsA family of gamma-butyrolactone regulatory genes

21 January 2018

1 reference

The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor

21 January 2018

1 reference

Structural relationships in the OmpR family of winged-helix transcription factors

21 January 2018

1 reference

A polyketide biosynthetic gene cluster from Streptomyces antibioticus includes a LysR-type transcriptional regulator

21 January 2018

1 reference

Transcriptional activation of the pathway-specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor

21 January 2018

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Regulation of daunorubicin production in Streptomyces peucetius by the dnrR2 locus

21 January 2018

1 reference

Regulation of secondary metabolism in Streptomyces spp. and overproduction of daunorubicin in Streptomyces peucetius

21 January 2018

1 reference

Mapping the DNA-binding domain and target sequences of the Streptomyces peucetius daunorubicin biosynthesis regulatory protein, DnrI.

21 January 2018

1 reference

The DnrN protein of Streptomyces peucetius, a pseudo-response regulator, is a DNA-binding protein involved in the regulation of daunorubicin biosynthesis

21 January 2018

1 reference

The dnrO gene encodes a DNA-binding protein that regulates daunorubicin production in Streptomyces peucetius by controlling expression of the dnrN pseudo response regulator gene

21 January 2018

1 reference

A repressor-response regulator gene pair controlling jadomycin B production in Streptomyces venezuelae ISP5230.

21 January 2018

1 reference

Production of landomycins in Streptomyces globisporus 1912 and S cyanogenus S136 is regulated by genes encoding putative transcriptional activators.

21 January 2018

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Involvement of AlpV, a new member of the Streptomyces antibiotic regulatory protein family, in regulation of the duplicated type II polyketide synthase alp gene cluster in Streptomyces ambofaciens.

21 January 2018

1 reference

The Streptomyces glaucescens TcmR protein represses transcription of the divergently oriented tcmR and tcmA genes by binding to an intergenic operator region

21 January 2018

1 reference

Biochemical activities of the absA two-component system of Streptomyces coelicolor

21 January 2018

1 reference

Primary and secondary metabolism, and post-translational protein modifications, as portrayed by proteomic analysis of Streptomyces coelicolor

21 January 2018

1 reference

Evidence from proteomics that some of the enzymes of actinorhodin biosynthesis have more than one form and may occupy distinctive cellular locations

21 January 2018

1 reference

A putative proteinase gene is involved in regulation of landomycin E biosynthesis inStreptomyces globisporus1912

21 January 2018

1 reference

‘Daunomycin’, a New Antibiotic of the Rhodomycin Group

21 January 2018

1 reference

Stoffwechselprodukte von Actinomyceten, XVI. Cinerubine

21 January 2018

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/CBER.19590920820

Urdamycin L: a novel metabolic shunt product that provides evidence for the role of the urdM gene in the urdamycin A biosynthetic pathway of Streptomyces fradiae TU 2717

1 reference

9 March 2024

https://opencitations.net/index/api/v1/citations/10.1002/CBIC.200390002

Structural and Biosynthetic Investigations of the Rubromycins

0 references

Resomycins A-C: New Anthracyclinone Antibiotics Formed by a Terrestrial Streptomyces sp.

1 reference

COCI

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.56.795

Identification of Four Genes from the Granaticin Biosynthetic Gene Cluster of Streptomyces violaceoruber Tue22 Involved in the Biosynthesis of L-Rhodinose.

12 April 2024

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.54.91

Collinone, a new recombinant angular polyketide antibiotic made by an engineered Streptomyces strain

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.54.239

Bequinostatins A and B new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activities

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.46.914

Benastatins C and D, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activities

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.46.712

R1128 substances, novel non-steroidal estrogen-receptor antagonists produced by a Streptomyces. II. Physico-chemical properties and structure determination

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.46.1063

Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. I. Taxonomy, production, isolation, physico-chemical properties and biological activities.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.45.1385

The structure of tetracenomycin C

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.45.1190

3-Alkanoyl-5-hydroxymethyl tetronic acid homologues and resistomycin: new inhibitors of HIV-1 protease. I. Fermentation, isolation and biological activity.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.47.136

Landomycins, new angucycline antibiotics from Streptomyces sp. I. Structural studies on landomycins A-D.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.43.492

Metabolic products of microorganisms. 240. Urdamycins, new angucycline antibiotics from Streptomyces fradiae. II. Structural studies of urdamycins B to F

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.40.459

Antitumor agents from Streptomyces anandii: gilvocarcins V, M and E.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.34.1544

Fredericamycin A, a new antitumor antibiotic. I. Production, isolation and physicochemical properties

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.34.1389

The Streptomyces peucetius dpsC Gene Determines the Choice of Starter Unit in Biosynthesis of the Daunorubicin Polyketide

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.181.15.4690-4695.1999

Doxorubicin overproduction in Streptomyces peucetius: cloning and characterization of the dnrU ketoreductase and dnrV genes and the doxA cytochrome P-450 hydroxylase gene

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.181.1.305-318.1999

Purification, properties, and characterization of recombinant Streptomyces sp. strain C5 DoxA, a cytochrome P-450 catalyzing multiple steps in doxorubicin biosynthesis

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1128/JB.181.1.298-304.1999

Identifiers

DOI

10.1039/B507395M

1 reference

release_osaivbhhrbc7rpmvci4o5unqie

15 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/osaivbhhrbc7rpmvci4o5unqie

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

17268612

1 reference

PubMed ID

17268612