The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii. (Q36730109)

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scientific article published on 19 January 2016

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English	The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii.	scientific article published on 19 January 2016

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scholarly article

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5 March 2020

The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii (English)

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5 March 2020

Cryptococcus gattii

1 reference

based on heuristic

inferred from title

Cryptococcus neoforman

1 reference

based on heuristic

inferred from title

Nathan Paul Wiederhold

12

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5 March 2020

Shawn R Lockhart

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object named as

Shawn R Lockhart

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5 March 2020

Thomas F Patterson

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Thomas F Patterson

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5 March 2020

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Annette W Fothergill

2

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5 March 2020

Naureen Iqbal

3

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5 March 2020

Carol B Bolden

4

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5 March 2020

Nina T Grossman

5

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5 March 2020

Edward P Garvey

6

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5 March 2020

Stephen R Brand

7

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5 March 2020

William J Hoekstra

8

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5 March 2020

Robert J Schotzinger

9

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5 March 2020

Elizabeth Ottinger

10

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5 March 2020

language of work or name

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publication date

25 March 2016

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5 March 2020

number of pages

4

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Antimicrobial Agents and Chemotherapy

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60

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2528-2531

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5 March 2020

4

1 reference

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5 March 2020

The clinical candidate VT-1161 is a highly potent inhibitor of Candida albicans CYP51 but fails to bind the human enzyme.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

30 September 2017

Epidemiologic cutoff values for triazole drugs in Cryptococcus gattii: correlation of molecular type and in vitro susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

30 September 2017

Trends in antifungal drug susceptibility of Cryptococcus neoformans isolates obtained through population-based surveillance in South Africa in 2002-2003 and 2007-2008.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

30 September 2017

In vitro antifungal susceptibilities and amplified fragment length polymorphism genotyping of a worldwide collection of 350 clinical, veterinary, and environmental Cryptococcus gattii isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

30 September 2017

Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

30 September 2017

Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

30 September 2017

Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

30 September 2017

Evaluation of Etest method for determining isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

30 September 2017

In vitro antifungal susceptibility of Cryptococcus gattii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

30 September 2017

Antifungal susceptibilities among different serotypes of Cryptococcus gattii and Cryptococcus neoformans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

28 June 2018

Antifungal susceptibility, serotyping, and genotyping of clinical Cryptococcus neoformans isolates collected during 18 years in a single institution in Madrid, Spain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

5 September 2018

Correlation of genotype and in vitro susceptibilities of Cryptococcus gattii strains from the Pacific Northwest of the United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

5 September 2018

In vitro susceptibilities of cerebrospinal fluid isolates of Cryptococcus neoformans collected during a ten-year period against fluconazole, voriconazole and posaconazole (SCH56592).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4808209

5 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26787697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Design and optimization of highly-selective fungal CYP51 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/26787697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.02770-15

1 reference

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5 March 2020

1 reference

Europe PubMed Central

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5 March 2020

1 reference

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5 March 2020

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