Rigid Adenine Nucleoside Derivatives as Novel Modulators of the Human Sodium Symporters for Dopamine and Norepinephrine. (Q36733500)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26813929%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Rigid Adenine Nucleoside Derivatives as Novel Modulators of the Human Sodium Symporters for Dopamine and Norepinephrine (English)

1 reference

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6 March 2020

0 references

Aaron Janowsky

1

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6 March 2020

Amy J Eshleman

series ordinal

3

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6 March 2020

language of work or name

English

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publication date

26 January 2016

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Journal of Pharmacology and Experimental Therapeutics

6 March 2020

published in

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6 March 2020

volume

357

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6 March 2020

issue

1

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6 March 2020

page(s)

24-35

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Structure-Based Design, Synthesis by Click Chemistry and in Vivo Activity of Highly Selective A3 Adenosine Receptor Agonists

6 March 2020

cites work

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Rigidified A3 Adenosine Receptor Agonists: 1-Deazaadenine Modification Maintains High in Vivo Efficacy

30 September 2017

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30 September 2017

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Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporter

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Computational and biochemical docking of the irreversible cocaine analog RTI 82 directly demonstrates ligand positioning in the dopamine transporter central substrate-binding site

30 September 2017

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30 September 2017

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Structural probing of off-target G protein-coupled receptor activities within a series of adenosine/adenine congeners

30 September 2017

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The two Na+ sites in the human serotonin transporter play distinct roles in the ion coupling and electrogenicity of transport

30 September 2017

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Binding of mazindol and analogs to the human serotonin and dopamine transporters

30 September 2017

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Structural basis for action by diverse antidepressants on biogenic amine transporters

30 September 2017

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X-ray structure of dopamine transporter elucidates antidepressant mechanism

30 September 2017

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Substituted methcathinones differ in transporter and receptor interactions

30 September 2017

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Nonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substrates

30 September 2017

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Comparative modeling of the human monoamine transporters: similarities in substrate binding.

30 September 2017

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Automated design of ligands to polypharmacological profiles.

30 September 2017

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Truncated Nucleosides as A(3) Adenosine Receptor Ligands: Combined 2-Arylethynyl and Bicyclohexane Substitutions

30 September 2017

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Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity

30 September 2017

1 reference

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Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions.

30 September 2017

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Controlling murine and rat chronic pain through A3 adenosine receptor activation

30 September 2017

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Colocalization and regulated physical association of presynaptic serotonin transporters with A₃ adenosine receptors

30 September 2017

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The binding sites for benztropines and dopamine in the dopamine transporter overlap.

30 September 2017

1 reference

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Studies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine release

30 September 2017

1 reference

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The binding sites for cocaine and dopamine in the dopamine transporter overlap

30 September 2017

1 reference

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Dopamine spillover after quantal release: rethinking dopamine transmission in the nigrostriatal pathway

30 September 2017

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Adenosine receptors as therapeutic targets

30 September 2017

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Monoamine transporter binding, locomotor activity, and drug discrimination properties of 3-(4-substituted-phenyl)tropane-2-carboxylic acid methyl ester isomers

30 September 2017

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Effect of psychotropic drugs on the uptake of H3-norepinephrine by tissues

30 September 2017

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Plasma membrane monoamine transporters: structure, regulation and function

30 September 2017

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Characteristics of drug interactions with recombinant biogenic amine transporters expressed in the same cell type

30 September 2017

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Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis

30 September 2017

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

30 September 2017

1 reference

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Cloning and expression of a cocaine-sensitive rat dopamine transporter

30 September 2017

1 reference

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Relationship between subjective effects of cocaine and dopamine transporter occupancy

30 September 2017

1 reference

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Association of dopamine transporter loss in the orbitofrontal and dorsolateral prefrontal cortices with methamphetamine-related psychiatric symptoms

28 June 2018

1 reference

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Striatal dopamine transporter binding in neuroleptic-naive patients with schizophrenia studied with positron emission tomography.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809312

[125I]RTI-55 binding to cocaine-sensitive dopaminergic and serotonergic uptake sites in the human brain.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4809312

A Second Extracellular Site Is Required for Norepinephrine Transport by the Human Norepinephrine Transporter

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26813929

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/JPET.115.229666

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26813929%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26813929%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

26813929

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26813929%20AND%20SRC:MED&resulttype=core&format=json