Emerging insights into Transforming growth factor beta Smad signal in hepatic fibrogenesis. (Q36736835)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303605%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

review article

1 reference

title

Emerging insights into Transforming growth factor beta Smad signal in hepatic fibrogenesis (English)

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25 December 2019

2

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25 December 2019

author name string

Y Inagaki

series ordinal

1

1 reference

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language of work or name

English

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publication date

1 February 2007

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25 December 2019

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25 December 2019

volume

56

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25 December 2019

issue

2

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25 December 2019

page(s)

284-292

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Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets

25 December 2019

cites work

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Smad transcription factors

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Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization

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Reciprocal modulation of matrix metalloproteinase-13 and type I collagen genes in rat hepatic stellate cells

29 September 2017

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BMP7 antagonizes TGF-beta -dependent fibrogenesis in mesangial cells

29 September 2017

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Smads 2 and 3 are differentially activated by transforming growth factor-beta (TGF-beta ) in quiescent and activated hepatic stellate cells. Constitutive nuclear localization of Smads in activated cells is TGF-beta-independent.

29 September 2017

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29 September 2017

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Y-box-binding protein YB-1 mediates transcriptional repression of human alpha 2(I) collagen gene expression by interferon-gamma

29 September 2017

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SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

29 September 2017

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Hepatocyte growth factor induces collagenase (matrix metalloproteinase-1) via the transcription factor Ets-1 in human hepatic stellate cell line

29 September 2017

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Differential regulation of TGF-beta signal in hepatic stellate cells between acute and chronic rat liver injury

29 September 2017

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Interaction between GC box binding factors and Smad proteins modulates cell lineage-specific alpha 2(I) collagen gene transcription

29 September 2017

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Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

29 September 2017

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Constitutive phosphorylation and nuclear localization of Smad3 are correlated with increased collagen gene transcription in activated hepatic stellate cells

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

29 September 2017

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Blockade of type beta transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat.

29 September 2017

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Transforming growth factor beta1 induces the expression of alpha1(I) procollagen mRNA by a hydrogen peroxide-C/EBPbeta-dependent mechanism in rat hepatic stellate cells

29 September 2017

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29 September 2017

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A proximal element within the human alpha 2(I) collagen (COL1A2) promoter, distinct from the tumor necrosis factor-alpha response element, mediates transcriptional repression by interferon-gamma

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Overlapping pathways mediate the opposing actions of tumor necrosis factor-alpha and transforming growth factor-beta on alpha 2(I) collagen gene transcription

29 September 2017

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A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations.

5 September 2018

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5 September 2018

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A blocking peptide for transforming growth factor-β1 activation prevents hepatic fibrosis in vivo

5 September 2018

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5 September 2018

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5 September 2018

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5 September 2018

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Modulation of transforming growth factor beta receptors of rat lipocytes during the hepatic wound healing response. Enhanced binding and reduced gene expression accompany cellular activation in culture and in vivo.

5 September 2018

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Regulation of the α2(I) collagen gene transcription in fat-storing cells derived from a cirrhotic liver

5 September 2018

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Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats

5 September 2018

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12 December 2020

Antagonistic regulation of type I collagen gene expression by interferon-gamma and transforming growth factor-beta. Integration at the level of p300/CBP transcriptional coactivators

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12 December 2020

Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression

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Transforming growth factor-beta signaling in stem cells and cancer

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Transforming growth factor-beta1 induces collagen synthesis and accumulation via p38 mitogen-activated protein kinase (MAPK) pathway in cultured L(6)E(9) myoblasts

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Gamma-interferon treatment inhibits collagen deposition in murine schistosomiasis.

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Interferon-alpha 2b therapy reduces liver fibrosis in chronic non-A, non-B hepatitis: a quantitative histological evaluation

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12 December 2020

Interferon alfa and gamma inhibit proliferation and collagen synthesis of human Ito cells in culture

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12 December 2020

Long-term decrease in serum N-terminal propeptide of type III procollagen in patients with chronic hepatitis C treated with interferon alfa

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12 December 2020

Hepatocyte growth factor suppresses the onset of liver cirrhosis and abrogates lethal hepatic dysfunction in rats

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Interferon gamma decreases hepatic stellate cell activation and extracellular matrix deposition in rat liver fibrosis

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12 December 2020

TGF-beta1 activates MAP kinase in human mesangial cells: a possible role in collagen expression

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12 December 2020

Interdependent SMAD and JNK signaling in transforming growth factor-beta-mediated transcription

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12 December 2020

A soluble transforming growth factor beta receptor expressed in muscle prevents liver fibrogenesis and dysfunction in rats

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12 December 2020

Identifiers

DOI

10.1136/GUT.2005.088690

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303605%20AND%20SRC:MED&resulttype=core&format=json

release_ykwinfq22zbgzm4pazrnaqoi2i

25 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ykwinfq22zbgzm4pazrnaqoi2i

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17303605%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

PubMed publication ID

17303605

1 reference