Hedgehog signaling: a biophysical or biomechanical modulator in embryonic development? (Q36748940)

16 August 2017

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title

Hedgehog signaling: a biophysical or biomechanical modulator in embryonic development? (English)

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16 August 2017

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Takashi Nagase

1

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16 August 2017

Miki Nagase

series ordinal

2

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16 August 2017

Masafumi Machida

series ordinal

3

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16 August 2017

Masaaki Yamagishi

series ordinal

4

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16 August 2017

language of work or name

English

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publication date

1 March 2007

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Annals of the New York Academy of Sciences

16 August 2017

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16 August 2017

1101

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16 August 2017

412-438

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Sonic hedgehog mediates the polarizing activity of the ZPA

16 August 2017

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

The hedgehog signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Hedgehog signaling in animal development: paradigms and principles

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Positional information and the spatial pattern of cellular differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Craniofacial anomalies of the cultured mouse embryo induced by inhibition of sonic hedgehog signaling: an animal model of holoprosencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Angiogenesis within the developing mouse neural tube is dependent on sonic hedgehog signaling: possible roles of motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Novel lipid modifications of secreted protein signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Patched acts catalytically to suppress the activity of Smoothened

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Sonic hedgehog induces the segregation of patched and smoothened in endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

The mechanism of hedgehog signal transduction

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

The Hedgehog signaling pathway as a target for anticancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Regulation of patched by sonic hedgehog in the developing neural tube

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Teratogen-mediated inhibition of target tissue response to Shh signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

A phase-shift model for the spatial and temporal organization of developing systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Diffusion in embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Conversion by retinoic acid of anterior cells into ZPA cells in the chick wing bud.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Retinoic acid induces polarizing activity but is unlikely to be a morphogen in the chick limb bud.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Neuronal specification in the spinal cord: inductive signals and transcriptional codes

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

A freely diffusible form of Sonic hedgehog mediates long-range signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Morphogens, their identification and regulation

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Lipoprotein particles are required for Hedgehog and Wingless signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Do morphogen gradients arise by diffusion?

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Self-enhanced ligand degradation underlies robustness of morphogen gradients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

The interpretation of morphogen gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

The reaction-diffusion system: a mechanism for autonomous pattern formation in the animal skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

TGFbeta2 acts as an "activator" molecule in reaction-diffusion model and is involved in cell sorting phenomenon in mouse limb micromass culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Molecular mechanisms regulating hair follicle development

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Local inhibitory action of BMPs and their relationships with activators in feather formation: implications for periodic patterning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Diverse initiation in a conserved left-right pathway?

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Left-right asymmetry in embryonic development: a comprehensive review

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Nodal flow and the generation of left-right asymmetry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Abnormal nodal flow precedes situs inversus in iv and inv mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

A two-cilia model for vertebrate left-right axis specification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Two populations of node monocilia initiate left-right asymmetry in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Tissue-specific RNA interference in postimplantation mouse embryos with endoribonuclease-prepared short interfering RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Mechanisms of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Vascular-specific growth factors and blood vessel formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Molecular regulation of vessel maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Hedgehog signaling in murine vasculogenesis and angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Sonic hedgehog induces capillary morphogenesis by endothelial cells through phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Positional signalling and specification of digits in chick limb morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Identification and spatial distribution of retinoids in the developing chick limb bud

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

A reaction-diffusion wave on the skin of the marine angelfish Pomacanthus

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

Determination of left–right patterning of the mouse embryo by artificial nodal flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1389.029

21 January 2018

Identifiers

DOI

10.1196/ANNALS.1389.029

1 reference

16 August 2017

1 reference