Extracellular heat shock protein 70 inhibits tumour necrosis factor-alpha induced proinflammatory mediator production in fibroblast-like synoviocytes. (Q36757020)

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scientific article published on 14 April 2008

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English	Extracellular heat shock protein 70 inhibits tumour necrosis factor-alpha induced proinflammatory mediator production in fibroblast-like synoviocytes.	scientific article published on 14 April 2008

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scholarly article

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5 January 2020

Extracellular heat shock protein 70 inhibits tumour necrosis factor-alpha induced proinflammatory mediator production in fibroblast-like synoviocytes (English)

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Xinjing Luo

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Xiaoxia Zuo

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Yaou Zhou

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Bing Zhang

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Meidong Liu

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Kangkai Wang

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D Randy McMillian

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Xianzhong Xiao

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14 April 2008

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5 January 2020

Arthritis Research and Therapy

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5 January 2020

R41

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https://scigraph.springernature.com/pub.10.1186/ar2399

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Heat shock proteins induce T cell regulation of chronic inflammation

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Releasing signals, secretory pathways, and immune function of endogenous extracellular heat shock protein 72.

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Heat shock proteins as endogenous adjuvants in sterile and septic inflammation

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Endogenous extra-cellular heat shock protein 72: releasing signal(s) and function.

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Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes

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Heat-shock proteins induce T-cell regulation of chronic inflammation

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Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production

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Inhibition of antigen-presenting cell function and stimulation of human peripheral blood mononuclear cells to express an antiinflammatory cytokine profile by the stress protein BiP: relevance to the treatment of inflammatory arthritis

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Cytokine function of heat shock proteins

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29 September 2017

The role of the interleukin‐6 family of cytokines in inflammatory arthritis and bone turnover

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29 September 2017

Cytokine mRNA and protein expression in primary-culture and repeated-passage synovial fibroblasts from patients with rheumatoid arthritis

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29 September 2017

Cytokine pathways and joint inflammation in rheumatoid arthritis

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29 September 2017

NF-kappaB: a key role in inflammatory diseases

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29 September 2017

A conserved mycobacterial heat shock protein (hsp) 70 sequence prevents adjuvant arthritis upon nasal administration and induces IL-10-producing T cells that cross-react with the mammalian self-hsp70 homologue

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29 September 2017

Anti-heat shock protein 70 kDa and 90 kDa antibodies in serum of patients with rheumatoid arthritis

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29 September 2017

Heat shock protein 70 kDa: molecular biology, biochemistry, and physiology

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29 September 2017

Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytoki

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29 September 2017

The human toll signaling pathway: divergence of nuclear factor kappaB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)

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29 September 2017

Discovery of the heat shock response

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29 September 2017

Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?

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29 September 2017

Cytokine expression and cell activation in inflammatory arthritis.

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29 September 2017

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

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29 September 2017

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

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29 September 2017

Vasoactive intestinal peptide modulates proinflammatory mediator synthesis in osteoarthritic and rheumatoid synovial cells

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28 June 2018

NF-kappa B regulation by I kappa B kinase in primary fibroblast-like synoviocytes

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28 June 2018

Transcriptional roles of CCAAT/enhancer binding protein-beta, nuclear factor-kappaB, and C-promoter binding factor 1 in interleukin (IL)-1beta-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes

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28 June 2018

Simvastatin inhibits production of interleukin 6 (IL-6) and IL-8 and cell proliferation induced by tumor necrosis factor-alpha in fibroblast-like synoviocytes from patients with rheumatoid arthritis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2453760

5 September 2018

Augmented production of chemokines by the interaction of type II collagen-reactive T cells with rheumatoid synovial fibroblasts.

1 reference

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5 September 2018

Elevated serum heat-shock protein 70 levels in patients with acute infection: use of an optimized enzyme-linked immunosorbent assay.

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5 September 2018

Aberrant extracellular and dendritic cell (DC) surface expression of heat shock protein (hsp)70 in the rheumatoid joint: possible mechanisms of hsp/DC-mediated cross-priming.

1 reference

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5 September 2018

Induction of IL-10 and inhibition of experimental arthritis are specific features of microbial heat shock proteins that are absent for other evolutionarily conserved immunodominant proteins

1 reference

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5 September 2018

Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1.

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5 September 2018

Expression of heat shock protein receptors on fibroblast-like synovial cells derived from rheumatoid arthritis-affected joints

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of severe rheumatoid arthritis by anti-interleukin 6 monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monocyte chemoattractant protein 1 and interleukin 8 production by rheumatoid synoviocytes. Effects of anti-rheumatic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear factor-kappa B in rheumatoid synovium. Localization of p50 and p65

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of transcription factor NF-kappa B in human synovial cells in response to tumor necrosis factor alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exaggerated human monocyte IL-10 concomitant to minimal TNF-alpha induction by heat-shock protein 27 (Hsp27) suggests Hsp27 is primarily an antiinflammatory stimulus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthr

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endotoxin-free heat-shock protein 70 fails to induce APC activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mycobacterial heat shock protein 70 induces interleukin-10 production: immunomodulation of synovial cell cytokine profile and dendritic cell maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock protein 60 inhibits Th1-mediated hepatitis model via innate regulation of Th1/Th2 transcription factors and cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock protein 70 membrane expression on fibroblast‐like synovial cells derived from synovial tissue of patients with rheumatoid and juvenile idiopathic arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18410682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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5 January 2020

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