Peroxisome proliferator-activated receptor alpha protects renal tubular cells from gentamicin-induced apoptosis via upregulating Na(+)/H(+) exchanger NHE1. (Q36758006)

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scientific article published on 23 November 2015

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English	Peroxisome proliferator-activated receptor alpha protects renal tubular cells from gentamicin-induced apoptosis via upregulating Na(+)/H(+) exchanger NHE1.	scientific article published on 23 November 2015

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1 March 2020

Peroxisome Proliferator-Activated Receptor α Protects Renal Tubular Cells from Gentamicin-Induced Apoptosis via Upregulating Na+/H+ Exchanger NHE1 (English)

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Cheng-Hsien Chen

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Tso-Hsiao Chen

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Jia-Rung Chen

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Li-Yu Hong

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Cai-Mei Zheng

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I-Jen Chiu

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Yuh-Feng Lin

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Yung-Ho Hsu

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23 November 2015

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Molecular Medicine

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886-889

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Creative Commons Attribution 4.0 International

1 January 2015

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https://scigraph.springernature.com/pub.10.2119/molmed.2015.00196

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Na+-H+ exchanger-1 (NHE1) regulation in kidney proximal tubule

1 reference

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29 September 2017

Intracellular Acid-extruding regulators and the effect of lipopolysaccharide in cultured human renal artery smooth muscle cells

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Regulation of energy metabolism by long-chain fatty acids

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29 September 2017

Role of the peroxisome proliferator-activated receptors (PPAR)-α, β/δ and γ triad in regulation of reactive oxygen species signaling in brain

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29 September 2017

Urotensin II exerts antiapoptotic effect on NRK-52E cells through prostacyclin-mediated peroxisome proliferator-activated receptor alpha and Akt activation

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Animal models of acute renal failure

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Far-infrared therapy induces the nuclear translocation of PLZF which inhibits VEGF-induced proliferation in human umbilical vein endothelial cells

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29 September 2017

Experimental gentamicin nephrotoxicity and agents that modify it: a mini-review of recent research

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An integrative overview on the mechanisms underlying the renal tubular cytotoxicity of gentamicin

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Pravastatin attenuates carboplatin-induced nephrotoxicity in rodents via peroxisome proliferator-activated receptor alpha-regulated heme oxygenase-1.

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Apoptosis and human diseases: mitochondrion damage and lethal role of released cytochrome C as proapoptotic protein

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29 September 2017

Peroxisome proliferator-activated receptor alpha plays a crucial role in L-carnitine anti-apoptosis effect in renal tubular cells

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Identification of a functional peroxisome proliferator-activated receptor (PPAR) response element (PPRE) in the human apolipoprotein A-IV gene

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Synergy between phosphatidylinositol 3-kinase/Akt pathway and Bcl-xL in the control of apoptosis in adenocarcinoma cells of the lung

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29 September 2017

Regulation of cell survival by Na+/H+ exchanger-1.

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Regulation of epithelial sodium transport by promyelocytic leukemia zinc finger protein

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Peroxisomal proliferator-activated receptor-alpha protects renal tubular cells from doxorubicin-induced apoptosis

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A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein

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Gentamicin causes apoptosis at low concentrations in renal LLC-PK1 cells subjected to electroporation

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Clinical and experimental evidence for prevention of acute renal failure induced by radiographic contrast media.

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Peroxisomal-proliferator-activated receptor alpha activates transcription of the rat hepatic malonyl-CoA decarboxylase gene: a key regulation of malonyl-CoA level

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Apoptosis induced by Na+/H+ antiport inhibition activates the LEI/L-DNase II pathway

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Renal tubular epithelial cell apoptosis is associated with caspase cleavage of the NHE1 Na+/H+ exchanger

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10.2119/MOLMED.2015.00196

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