Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination (Q36759880)

16 August 2017

Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination (English)

1 reference

16 August 2017

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Shahnaz Masani

1

1 reference

16 August 2017

Li Han

series ordinal

2

1 reference

16 August 2017

Kefei Yu

series ordinal

3

1 reference

16 August 2017

language of work or name

English

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publication date

4 February 2013

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Molecular and Cellular Biology

16 August 2017

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16 August 2017

33

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16 August 2017

7

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16 August 2017

1468-1473

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describes a project that uses

16 August 2017

CH12F3 (APE1-/-/-APE2-)

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CH12F3 (APE2-)

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cites work

X-ray repair cross-complementing protein 1 (XRCC1) deficiency enhances class switch recombination and is permissive for alternative end joining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Overlapping activation-induced cytidine deaminase hotspot motifs in Ig class-switch recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Cutting edge: CTNNBL1 is dispensable for Ig class switch recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV-deficient B cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Dependence of antibody gene diversification on uracil excision.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Human Ape2 protein has a 3'-5' exonuclease activity that acts preferentially on mismatched base pairs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Antibody class switch recombination: roles for switch sequences and mismatch repair proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Two essential but distinct functions of the mammalian abasic endonuclease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

A vital role for Ape1/Ref1 protein in repairing spontaneous DNA damage in human cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Nucleic acid structures and enzymes in the immunoglobulin class switch recombination mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

The Sμ Tandem Repeat Region Is Critical for Ig Isotype Switching in the Absence of Msh2

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Hyper-IgM syndrome type 4 with a B lymphocyte-intrinsic selective deficiency in Ig class-switch recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Characterization of the genomic structure and expression of the mouse Apex2 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Uracil in DNA--occurrence, consequences and repair

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Repair of oxidative damage to DNA: enzymology and biology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Endonucleolytic function of MutLalpha in human mismatch repair.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3624277

Second human protein with homology to the Escherichia coli abasic endonuclease exonuclease III

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23382073

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23382073

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of Apex2 in class-switch recombination of immunoglobulin genes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23382073

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.00026-13

1 reference

16 August 2017

1 reference

16 August 2017

1 reference