Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic mice (Q36761860)

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6 January 2020

title

Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic mice (English)

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hypertrophic cardiomyopathy

6 January 2020

main subject

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2

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6 January 2020

author name string

Yuhui Wen

1

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6 January 2020

Aldrin V Gomes

3

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6 January 2020

Yuanyuan Xu

4

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6 January 2020

Yingcai Wang

5

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6 January 2020

Ying Wang

6

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6 January 2020

James D Potter

7

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6 January 2020

W Glenn L Kerrick

8

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6 January 2020

language of work or name

English

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publication date

22 April 2008

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Journal of Biological Chemistry

6 January 2020

published in

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6 January 2020

volume

283

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6 January 2020

issue

29

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6 January 2020

page(s)

20484-20494

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Transgenic rabbit model for human troponin I-based hypertrophic cardiomyopathy

6 January 2020

cites work

1 reference

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Molecular and cellular aspects of troponin cardiomyopathies

29 September 2017

1 reference

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Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategy

29 September 2017

1 reference

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Myofilament calcium sensitivity and cardiac disease: insights from troponin I isoforms and mutants

29 September 2017

1 reference

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Functional consequences of the mutations in human cardiac troponin I gene found in familial hypertrophic cardiomyopathy

29 September 2017

1 reference

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The Genetic Basis for Cardiomyopathy

29 September 2017

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An abnormal Ca(2+) response in mutant sarcomere protein-mediated familial hypertrophic cardiomyopathy

29 September 2017

1 reference

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Altered regulatory properties of human cardiac troponin I mutants that cause hypertrophic cardiomyopathy

29 September 2017

1 reference

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Mutations in the cardiac troponin I gene associated with hypertrophic cardiomyopathy

29 September 2017

1 reference

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Report of the WHO/ISFC task force on the definition and classification of cardiomyopathies

29 September 2017

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A fluorescent probe study of Ca2+ binding to the Ca2+-specific sites of cardiac troponin and troponin C

29 September 2017

1 reference

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The kinetics of magnesium adenosine triphosphate cleavage in skinned muscle fibres of the rabbit

29 September 2017

1 reference

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Molecular cloning of mRNA sequences for cardiac alpha- and beta-form myosin heavy chains: expression in ventricles of normal, hypothyroid, and thyrotoxic rabbits

29 September 2017

1 reference

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Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs

29 September 2017

1 reference

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Characterization of the effects of Mg2+ on Ca2+- and Sr2+-activated tension generation of skinned skeletal muscle fibers

29 September 2017

1 reference

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A fluorimetric method for continuously assaying ATPase: Application to small specimens of glycerol-extracted muscle fibers

29 September 2017

1 reference

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Two mutations in troponin I that cause hypertrophic cardiomyopathy have contrasting effects on cardiac muscle contractility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459290

Troponin, tropomyosin, and actin interactions in the Ca2+ regulation of muscle contraction

28 June 2018

1 reference

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Calcium-independent negative inotropy by beta-myosin heavy chain gene transfer in cardiac myocytes.

28 June 2018

1 reference

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F110I and R278C troponin T mutations that cause familial hypertrophic cardiomyopathy affect muscle contraction in transgenic mice and reconstituted human cardiac fibers

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459290

Effects of the mutation R145G in human cardiac troponin I on the kinetics of the contraction-relaxation cycle in isolated cardiac myofibrils

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459290

Impact of beta-myosin heavy chain expression on cardiac function during stress

5 September 2018

1 reference

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Inorganic phosphate affects the pCa-force relationship more than the pCa-ATPase by increasing the rate of dissociation of force generating cross-bridges in skinned fibers from both EDL and soleus muscles of the rat.

5 September 2018

1 reference

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Prevalence and spectrum of thin filament mutations in an outpatient referral population with hypertrophic cardiomyopathy

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459290

Familial hypertrophic cardiomyopathy mutations in troponin I (K183D, G203S, K206Q) enhance filament sliding

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459290

Activation of striated muscle: nearest-neighbor regulatory-unit and cross-bridge influence on myofilament kinetics

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2459290

Functional analysis of a troponin I (R145G) mutation associated with familial hypertrophic cardiomyopathy

5 September 2018

1 reference

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The genetic basis for cardiomyopathy: from mutation identification to mechanistic paradigms

5 September 2018

1 reference

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Molecular genetic basis of hypertrophic cardiomyopathy: genetic markers for sudden cardiac death

5 September 2018

1 reference

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The off rate of Ca(2+) from troponin C is regulated by force-generating cross bridges in skeletal muscle

5 September 2018

1 reference

12 December 2020

Troponin and tropomyosin: proteins that switch on and tune in the activity of cardiac myofilaments

1 reference

12 December 2020

Increased Ca2+ affinity of cardiac thin filaments reconstituted with cardiomyopathy-related mutant cardiac troponin I

1 reference

12 December 2020

Prolonged Ca2+ and force transients in myosin RLC transgenic mouse fibers expressing malignant and benign FHC mutations

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12 December 2020

[Echocardiography in athletes]

1 reference

12 December 2020

Familial hypertrophic cardiomyopathy mutations from different functional regions of troponin T result in different effects on the pH and Ca2+ sensitivity of cardiac muscle contraction

1 reference

12 December 2020

Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathy

1 reference

12 December 2020

Ca(2+) measurements in skinned cardiac fibers: effects of Mg(2+) on Ca(2+) activation of force and fiber ATPase

1 reference

12 December 2020

Troponin C regulates the rate constant for the dissociation of force-generating myosin cross-bridges in cardiac muscle

1 reference

12 December 2020

Effect of Arg145Gly mutation in human cardiac troponin I on the ATPase activity of cardiac myofibrils

1 reference

12 December 2020

Deletion in the cardiac troponin I gene in a family from northern Sweden with hypertrophic cardiomyopathy

1 reference

12 December 2020

Clinical features of hypertrophic cardiomyopathy caused by a Lys183 deletion mutation in the cardiac troponin I gene

1 reference

12 December 2020

Transgenic modeling of a cardiac troponin I mutation linked to familial hypertrophic cardiomyopathy

1 reference

12 December 2020

Perfusion cuvette for the simultaneous measurement of mechanical, optical and energetic parameters of skinned muscle fibres

1 reference

12 December 2020

Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M801661200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18430738%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18430738%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

18430738

1 reference