Roles of CREB-binding protein (CBP)/p300 in respiratory epithelium tumorigenesis (Q36764481)

16 August 2017

title

Roles of CREB-binding protein (CBP)/p300 in respiratory epithelium tumorigenesis (English)

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16 August 2017

author name string

Michalis V Karamouzis

series ordinal

1

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16 August 2017

Panagiotis A Konstantinopoulos

series ordinal

2

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16 August 2017

Athanasios G Papavassiliou

series ordinal

3

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16 August 2017

publication date

1 April 2007

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16 August 2017

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16 August 2017

volume

17

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16 August 2017

issue

4

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16 August 2017

page(s)

324-332

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https://scigraph.springernature.com/pub.10.1038/cr.2007.10

16 August 2017

exact match

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Phosphorylated CREB binds specifically to the nuclear protein CBP

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Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor

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Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300

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Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: implications for a dominant-negative mechanism

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Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

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Rubinstein-Taybi syndrome caused by a De Novo reciprocal translocation t(2;16)(q36.3;p13.3).

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Recruitment of CBP/p300 by the IFN beta enhanceosome is required for synergistic activation of transcription

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Chromatin-modulating agents as epigenetic anticancer drugs--'the die is cast'

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p300 forms a stable, template-committed complex with chromatin: role for the bromodomain

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Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators

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CBP and p300: HATs for different occasions

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Acetylation of nuclear receptors in cellular growth and apoptosis

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Stat3 activation of NF-{kappa}B p100 processing involves CBP/p300-mediated acetylation

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p300 regulates androgen receptor-independent expression of prostate-specific antigen in prostate cancer cells treated chronically with interleukin-6

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Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription

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Histone-like TAFs within the PCAF histone acetylase complex

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Physical association between the histone acetyl transferase CBP and a histone methyl transferase

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A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors

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Induction of the CBP transcriptional co-activator early during laryngeal carcinogenesis.

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A family of transcriptional adaptor proteins targeted by the E1A oncoprotein

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The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300.

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Phosphorylation by p44 MAP Kinase/ERK1 stimulates CBP histone acetyl transferase activity in vitro

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7 January 2021

Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity

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Control of CBP co-activating activity by arginine methylation

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p300 Transcriptional Repression Is Mediated by SUMO Modification

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Regulation of the p300 HAT domain via a novel activation loop.

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HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription

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E6 oncoprotein represses p53-dependent gene activation via inhibition of protein acetylation independently of inducing p53 degradation

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A mechanism for coordinating chromatin modification and preinitiation complex assembly.

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Synergistic functions of SII and p300 in productive activator-dependent transcription of chromatin templates

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Mutation analysis of CBP and PCAF reveals rare inactivating mutations in cancer cell lines but not in primary tumours

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Cytogenetic and molecular aspects of lung cancer

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Mutations truncating the EP300 acetylase in human cancers

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Growth suppression of human carcinoma cells by reintroduction of the p300 coactivator

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The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression

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Roles for the coactivators CBP and p300 and the APC/C E3 ubiquitin ligase in E1A-dependent cell transformation

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The p53 response: emerging levels of co-factor complexity.

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p53 and its downstream proteins as molecular targets of cancer

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p53 Transcriptional activity is mediated through the SRC1-interacting domain of CBP/p300

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Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators

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p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

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p300/MDM2 complexes participate in MDM2-mediated p53 degradation

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7 January 2021

Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

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7 January 2021

Involvement of E2F transcription factor family in cancer

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Transcription factor E2F-1 acts as a growth-promoting factor and is associated with adverse prognosis in non-small cell lung carcinomas

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7 January 2021

Forkhead box M1B transcriptional activity requires binding of Cdk-cyclin complexes for phosphorylation-dependent recruitment of p300/CBP coactivators

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7 January 2021

Specific role for p300/CREB-binding protein-associated factor activity in E2F1 stabilization in response to DNA damage

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7 January 2021

Retinoid receptor cross-talk in respiratory epithelium cancer chemoprevention

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7 January 2021

Minireview: Cyclin D1: normal and abnormal functions

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7 January 2021

Cyclin D1 represses p300 transactivation through a cyclin-dependent kinase-independent mechanism

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7 January 2021

COX-2 inhibition in cancer therapeutics: a field of controversy or a magic bullet?

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7 January 2021

Retinoid-X-receptor alpha (RXRalpha) expression during laryngeal carcinogenesis: detrimental or beneficial event?

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7 January 2021

Antisense molecules for targeted cancer therapy

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7 January 2021

siRNA and isRNA: two edges of one sword

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7 January 2021

Targeting protein-protein interactions with small molecules: challenges and perspectives for computational binding epitope detection and ligand finding

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7 January 2021

Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth

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7 January 2021

Anticancer activities of histone deacetylase inhibitors

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7 January 2021

HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF.

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7 January 2021

Synthesis and analysis of potential prodrugs of coenzyme A analogues for the inhibition of the histone acetyltransferase p300

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Bisubstrate analogue structure-activity relationships for p300 histone acetyltransferase inhibitors

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7 January 2021

Small molecule modulators of histone acetyltransferase p300.

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7 January 2021

Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation

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7 January 2021

Implications of small molecule activators and inhibitors of histone acetyltransferases in chromatin therapy

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7 January 2021

Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription

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7 January 2021

Polyisoprenylated benzophenone, garcinol, a natural histone acetyltransferase inhibitor, represses chromatin transcription and alters global gene expression

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7 January 2021

Isothiazolones as inhibitors of PCAF and p300 histone acetyltransferase activity

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7 January 2021

Identifiers

DOI

10.1038/CR.2007.10

1 reference

16 August 2017

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