Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells (Q36765250)

16 August 2017

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells (English)

1 reference

single cell transcriptomics

16 August 2017

1 reference

1 reference

A curated database reveals trends in single-cell transcriptomics

https://www.nxn.se/single-cell-studies/data.tsv

7 February 2021

Supat Thongjuea

3

0 references

Alice Giustacchini

Alice Giustacchini

5

0 references

Tiago C Luis

Tiago C Luis

9

0 references

Iain C Macaulay

Iain Macaulay

7

0 references

Adam J Mead

Adam Mead

10

0 references

Sten Eirik W Jacobsen

Sten Eirik W Jacobsen

11

0 references

Amit Grover

1

Amit Grover

1 reference

16 August 2017

Alejandra Sanjuan-Pla

2

Alejandra Sanjuan-Pla

1 reference

16 August 2017

12

Claus Nerlov

1 reference

16 August 2017

Joana Carrelha

4

1 reference

16 August 2017

Adriana Gambardella

6

1 reference

16 August 2017

Elena Mancini

8

1 reference

16 August 2017

language of work or name

English

0 references

publication date

24 March 2016

1 reference

external data available at URL

16 August 2017

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE70657

1 reference

A curated database reveals trends in single-cell transcriptomics

https://www.nxn.se/single-cell-studies/data.tsv

7 February 2021

published in

Nature Communications

1 reference

16 August 2017

7

1 reference

16 August 2017

11075

1 reference

Creative Commons Attribution 4.0 International

16 August 2017

start time

24 March 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms11075

0 references

cites work

Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in Bcl11a-deficient hematopoietic stem cells

1 reference

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A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.

29 September 2017

1 reference

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TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

29 September 2017

1 reference

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Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation

29 September 2017

1 reference

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Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing

29 September 2017

1 reference

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Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.

29 September 2017

1 reference

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Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Immunoaging induced by hematopoietic stem cell aging.

29 September 2017

1 reference

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Aging of hematopoietic stem cells: Intrinsic changes or micro-environmental effects?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Emerging models and paradigms for stem cell ageing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

An abundance of ubiquitously expressed genes revealed by tissue transcriptome sequence data

29 September 2017

1 reference

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edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

29 September 2017

1 reference

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A novel assay to trace proliferation history in vivo reveals that enhanced divisional kinetics accompany loss of hematopoietic stem cell self-renewal

29 September 2017

1 reference

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A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells

29 September 2017

1 reference

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Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

29 September 2017

1 reference

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Long-term propagation of distinct hematopoietic differentiation programs in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

29 September 2017

SnapShot: hematopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

The hematopoietic stem compartment consists of a limited number of discrete stem cell subsets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Cell intrinsic alterations underlie hematopoietic stem cell aging.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Endothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Inducible gene targeting in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Age-associated characteristics of murine hematopoietic stem cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Identification of clonogenic common lymphoid progenitors in mouse bone marrow

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

The aging of hematopoietic stem cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Heterogeneity of young and aged murine hematopoietic stem cells revealed by quantitative clonal analysis using cellular barcoding.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Effect of ageing on the murine venous circulation

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Deterministic regulation of hematopoietic stem cell self-renewal and differentiation.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Hematopoiesis: an evolving paradigm for stem cell biology

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS11075

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4820843

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

4 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27009448

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Anemia in the elderly

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27009448

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS11075

1 reference

16 August 2017

0 references

1 reference

16 August 2017

1 reference