Alternative splicing: an emerging topic in molecular and clinical oncology (Q36774636)

16 August 2017

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title

Alternative splicing: an emerging topic in molecular and clinical oncology (English)

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alternative mRNA splicing, via spliceosome

16 August 2017

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Ruben Pio

5

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Alfonso Calvo

object named as

Alfonso Calvo

4

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author name string

María J Pajares

1

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16 August 2017

Teresa Ezponda

2

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16 August 2017

Raúl Catena

3

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16 August 2017

Luis M Montuenga

6

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16 August 2017

1 April 2007

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Lancet Oncology Commission

16 August 2017

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16 August 2017

8

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16 August 2017

4

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16 August 2017

349-357

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A genomic view of alternative splicing

16 August 2017

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Alternative splicing: multiple control mechanisms and involvement in human disease

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Pre-mRNA splicing and human disease

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Alternative splicing in disease and therapy

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Mechanisms of alternative pre-messenger RNA splicing

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Listening to silence and understanding nonsense: exonic mutations that affect splicing

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

hnRNP proteins and the biogenesis of mRNA

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Unbalanced alternative splicing and its significance in cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Altered patterns of expression of members of the heterogeneous nuclear ribonucleoprotein (hnRNP) family in lung cancer.

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Predicting splice variant from DNA chip expression data

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

A statistical method for predicting splice variants between two groups of samples using GeneChip expression array data

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Genomewide analysis of mRNA processing in yeast using splicing-specific microarrays

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

A microarray configuration to quantify expression levels and relative abundance of splice variants

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Profiling alternative splicing on fiber-optic arrays

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Detection of alternatively spliced transcripts in leukemia cell lines by minisequencing on microarrays

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

ASAP: the Alternative Splicing Annotation Project

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Alterations of pre-mRNA splicing in cancer.

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Aberrant and alternative splicing in cancer

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Regulation of apoptosis by alternative pre-mRNA splicing

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Alternative splicing: new insights from global analyses

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Mutations affecting mRNA splicing are the most common molecular defects in patients with neurofibromatosis type 1.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Splicing defects in the ataxia-telangiectasia gene, ATM: underlying mutations and consequences

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Building specificity with nonspecific RNA-binding proteins

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

1 reference

7 January 2021

Stage-specific changes in SR splicing factors and alternative splicing in mammary tumorigenesis

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Relative amounts of antagonistic splicing factors, hnRNP A1 and ASF/SF2, change during neoplastic lung growth: implications for pre-mRNA processing

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Levels of soluble Fas/APO-1/CD95 in systemic lupus erythematosus and juvenile rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Differential regulation of survivin expression and apoptosis by vitamin D3 compounds in two isogenic MCF-7 breast cancer cell sublines

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

An alternatively spliced survivin variant is positively regulated by p53 and sensitizes leukemia cells to chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Expression of different survivin variants in gastric carcinomas: first clues to a role of survivin-2B in tumour progression

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

An alternative splice form of Mdm2 induces p53-independent cell growth and tumorigenesis.

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing.

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

The biology of VEGF and its receptors

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Isoforms of vascular endothelial growth factor act in a coordinate fashion To recruit and expand tumor vasculature.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

The 121 amino acid isoform of vascular endothelial growth factor is more strongly tumorigenic than other splice variants in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

VEGF165b, an inhibitory vascular endothelial growth factor splice variant: mechanism of action, in vivo effect on angiogenesis and endogenous protein expression

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Splice variants as cancer biomarkers

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Role of survivin and its splice variants in tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Significance of HDMX-S (or MDM4) mRNA splice variant overexpression and HDMX gene amplification on primary soft tissue sarcoma prognosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Biological and clinical role of p73 in neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Association between HER-2/neu and vascular endothelial growth factor expression predicts clinical outcome in primary breast cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Two-dimensional transcriptome profiling: identification of messenger RNA isoform signatures in prostate cancer from archived paraffin-embedded cancer specimens

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

The relevance of alternative RNA splicing to pharmacogenomics

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https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Oncomirs - microRNAs with a role in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Antisense therapy for cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Phase III study of gemcitabine and cisplatin with or without aprinocarsen, a protein kinase C-alpha antisense oligonucleotide, in patients with advanced-stage non-small-cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Spliceosome-mediated RNA trans-splicing as a tool for gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Efficient in vivo gene expression by trans-splicing adeno-associated viral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Safety, biodistribution, pharmacokinetics, and immunogenicity of 99mTc-labeled humanized monoclonal antibody BIWA 4 (bivatuzumab) in patients with squamous cell carcinoma of the head and neck

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Tumor-targeting properties of novel antibodies specific to the large isoform of tenascin-C.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Manipulation of alternative splicing by a newly developed inhibitor of Clks

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

Targeting the RNA splicing machinery as a novel treatment strategy for pancreatic carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2807%2970104-3

7 January 2021

10.1016/S1470-2045(07)70104-3

Identifiers

DOI

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16 August 2017

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