Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function? (Q36777361)

16 August 2017

Are interactions with p63 and p73 involved in mutant p53 gain of oncogenic function? (English)

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16 August 2017

Y Li

1

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16 August 2017

C Prives

series ordinal

2

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16 August 2017

language of work or name

English

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publication date

1 April 2007

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16 August 2017

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16 August 2017

26

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16 August 2017

2220-2225

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16 August 2017

15

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210311

16 August 2017

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cites work

Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis

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p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

21 January 2018

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ASPP1 and ASPP2: common activators of p53 family members

21 January 2018

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P63 gene mutations and human developmental syndromes.

21 January 2018

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Dissecting p53-dependent apoptosis.

21 January 2018

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

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p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation

21 January 2018

1 reference

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A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

21 January 2018

1 reference

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Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

21 January 2018

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TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

21 January 2018

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AIS is an oncogene amplified in squamous cell carcinoma

21 January 2018

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Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

21 January 2018

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Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

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Transcriptional regulation by p53: one protein, many possibilities

21 January 2018

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p53 and p73 display common and distinct requirements for sequence specific binding to DNA

21 January 2018

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Transcriptional regulation by p53 and p73.

21 January 2018

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A common polymorphism acts as an intragenic modifier of mutant p53 behaviour

21 January 2018

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p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.

21 January 2018

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Cloning and functional analysis of human p51, which structurally and functionally resembles p53

21 January 2018

1 reference

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Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

21 January 2018

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p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

21 January 2018

1 reference

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ASPP proteins specifically stimulate the apoptotic function of p53

21 January 2018

1 reference

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Physical interaction with human tumor-derived p53 mutants inhibits p63 activities.

21 January 2018

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Physical interaction with Yes-associated protein enhances p73 transcriptional activity

21 January 2018

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p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2.

21 January 2018

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21 January 2018

1 reference

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21 January 2018

Surfing the p53 network

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Live or let die: the cell's response to p53

21 January 2018

1 reference

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p73 can suppress the proliferation of cells that express mutant p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Strategies for therapeutic targeting of the p53 pathway in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Hot-spot mutants of p53 core domain evince characteristic local structural changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

On the shoulders of giants: p63, p73 and the rise of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

SSRP1 functions as a co-activator of the transcriptional activator p63

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

Physical and Functional Interaction between p53 Mutants and Different Isoforms of p73

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

7 January 2021

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

7 January 2021

Chemosensitivity linked to p73 function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

7 January 2021

Cross-talks in the p53 family: deltaNp63 is an anti-apoptotic target for deltaNp73alpha and p53 gain-of-function mutants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

7 January 2021

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210311

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210311

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release_uqfbdippgja6rfelsswikpslny

16 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/uqfbdippgja6rfelsswikpslny

24 November 2022

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