Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytes (Q36783666)

16 August 2017

Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans-rearrangements in ATM-deficient thymocytes (English)

1 reference

16 August 2017

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5

Richard J Hodes

1 reference

16 August 2017

Steven Bowen

1

1 reference

16 August 2017

Darawalee Wangsa

series ordinal

2

1 reference

16 August 2017

Thomas Ried

series ordinal

3

1 reference

16 August 2017

Ferenc Livak

series ordinal

4

1 reference

16 August 2017

language of work or name

English

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publication date

6 March 2013

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16 August 2017

Nucleic Acids Research

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16 August 2017

41

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16 August 2017

8

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16 August 2017

4535-4548

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Creative Commons Attribution-NonCommercial 3.0 Unported

16 August 2017

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Spatial organization of the mouse genome and its role in recurrent chromosomal translocations

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DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes

29 September 2017

1 reference

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V(D)J recombination: mechanisms of initiation

29 September 2017

1 reference

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ATM Limits Incorrect End Utilization during Non-Homologous End Joining of Multiple Chromosome Breaks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Fluorescence in situ hybridization markers for prediction of cervical lymph node metastases

29 September 2017

1 reference

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Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Mechanisms promoting translocations in editing and switching peripheral B cells

29 September 2017

1 reference

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Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.

29 September 2017

1 reference

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RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

29 September 2017

1 reference

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MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks

29 September 2017

1 reference

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53BP1 facilitates long-range DNA end-joining during V(D)J recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

ATM prevents the persistence and propagation of chromosome breaks in lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

ATM deficiency impairs thymocyte maturation because of defective resolution of T cell receptor alpha locus coding end breaks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Spatial genome organization in the formation of chromosomal translocations

29 September 2017

1 reference

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ATM stabilizes DNA double-strand-break complexes during V(D)J recombination.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Beyond the 12/23 rule of VDJ recombination independent of the Rag proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Direct in vivo VH to JH rearrangement violating the 12/23 rule

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

53BP1 is required for class switch recombination

29 September 2017

1 reference

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Chromosome positioning in the interphase nucleus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Atm-deficient mice: a paradigm of ataxia telangiectasia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Leukemia and lymphoma in ataxia telangiectasia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Somatic generation of antibody diversity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

A chromosome 14 inversion in a T-cell lymphoma is caused by site-specific recombination between immunoglobulin and T-cell receptor loci

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Simultaneous visualization of seven different DNA probes by in situ hybridization using combinatorial fluorescence and digital imaging microscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasis lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Interlocus V-J recombination measures genomic instability in agriculture workers at risk for lymphoid malignancies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Violations of the 12/23 rule at the mouse immunoglobulin kappa locus, including V kappa-V kappa rearrangement

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Characterization of TCR gene rearrangements during adult murine T cell development.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Inversion of chromosome 7 in ataxia telangiectasia is generated by a rearrangement between T-cell receptor beta and T-cell receptor gamma genes

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3632137

Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice

27 June 2018

1 reference

12 December 2020

Spatial proximity of translocation-prone gene loci in human lymphomas

1 reference

12 December 2020

High frequencies of inversions and translocations of chromosomes 7 and 14 in ataxia telangiectasia

1 reference

12 December 2020

The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk: a severe combined immune deficiency (SCID) murine model

1 reference

12 December 2020

On the contribution of spatial genome organization to cancerous chromosome translocations

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKT154

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

23470994

1 reference