SRSF3 and hnRNP H1 regulate a splicing hotspot of HER2 in breast cancer cells. (Q36791562)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26367347%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

SRSF3 and hnRNP H1 regulate a splicing hotspot of HER2 in breast cancer cells (English)

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24 February 2020

1

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author name string

Claire Jackson

2

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24 February 2020

Anna-Lena Dittrich

3

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24 February 2020

David Browell

4

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24 February 2020

Thomas Lennard

5

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24 February 2020

Alison Tyson-Capper

6

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24 February 2020

publication date

14 September 2015

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24 February 2020

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24 February 2020

volume

12

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24 February 2020

issue

10

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24 February 2020

page(s)

1139-1151

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The HER2 Signaling Network in Breast Cancer--Like a Spider in its Web.

24 February 2020

cites work

1 reference

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Exon 9 skipping of apoptotic caspase-2 pre-mRNA is promoted by SRSF3 through interaction with exon 8

29 September 2017

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Clinical Significance of HER-2 Splice Variants in Breast Cancer Progression and Drug Resistance.

29 September 2017

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Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells

29 September 2017

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Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F

29 September 2017

1 reference

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Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence

29 September 2017

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29 September 2017

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Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins

29 September 2017

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Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

29 September 2017

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The human splice variant Δ16HER2 induces rapid tumor onset in a reporter transgenic mouse.

29 September 2017

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SRp20 is a proto-oncogene critical for cell proliferation and tumor induction and maintenance

29 September 2017

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Knockdown of splicing factor SRp20 causes apoptosis in ovarian cancer cells and its expression is associated with malignancy of epithelial ovarian cancer

29 September 2017

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Molecular mechanisms of eukaryotic pre-mRNA 3' end processing regulation

29 September 2017

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Splice site strength-dependent activity and genetic buffering by poly-G runs

29 September 2017

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Trastuzumab in the management of early and advanced stage breast cancer.

29 September 2017

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An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance

29 September 2017

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A physical and functional link between splicing factors promotes pre-mRNA 3' end processing

29 September 2017

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A naturally occurring HER2 carboxy-terminal fragment promotes mammary tumor growth and metastasis

29 September 2017

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Multiple and specific mRNA processing targets for the major human hnRNP proteins

29 September 2017

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Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation.

29 September 2017

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Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

29 September 2017

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Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissues

29 September 2017

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Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

29 September 2017

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The HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitor

29 September 2017

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Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer

29 September 2017

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Regulation of alternative polyadenylation by U1 snRNPs and SRp20.

29 September 2017

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ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

29 September 2017

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A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor

29 September 2017

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29 September 2017

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A truncated intracellular HER2/neu receptor produced by alternative RNA processing affects growth of human carcinoma cells

29 September 2017

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29 September 2017

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Downregulation of serine/arginine-rich splicing factor 3 induces G1 cell cycle arrest and apoptosis in colon cancer cells.

29 September 2017

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RNase-assisted RNA chromatography

27 June 2018

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Role of exon-16-deleted HER2 in breast carcinomas

27 June 2018

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Mammary tumor formation and metastasis evoked by a HER2 splice variant

27 June 2018

1 reference

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The expression profile of RNA-binding proteins in primary and metastatic colorectal cancer: relationship of heterogeneous nuclear ribonucleoproteins with prognosis

5 September 2018

1 reference

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A novel splice variant of HER2 with increased transformation activity

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4829299

Expression of a truncated 100 kDa HER2 splice variant acts as an endogenous inhibitor of tumour cell proliferation

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26367347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Heterogeneous nuclear ribonucleoprotein F/H proteins modulate the alternative splicing of the apoptotic mediator Bcl-x

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26367347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1080/15476286.2015.1076610

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26367347%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26367347%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

26367347

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26367347%20AND%20SRC:MED&resulttype=core&format=json