Regulation of the cell cycle following DNA damage in normal and Ataxia telangiectasia cells (Q36797925)

16 August 2017

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title

Regulation of the cell cycle following DNA damage in normal and Ataxia telangiectasia cells (English)

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16 August 2017

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ataxia telangiectasia

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H D Lohrer

1

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16 August 2017

1 April 1996

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16 August 2017

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16 August 2017

52

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16 August 2017

4

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16 August 2017

316-328

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Comparison of gamma-radiation-induced accumulation of ataxia telangiectasia and control cells in G2 phase.

16 August 2017

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https://api.crossref.org/works/10.1007%2FBF01919534

Evidence of different complementation groups amongst human genetic disorders characterized by radiosensitivity

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF01919534

Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Enhanced induction of tissue-type plasminogen activator in normal human cells compared to cancer-prone cells following ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Genetic analysis of ionising radiation sensitive mutants of cultured mammalian cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Overproduction of Rb protein after the G1/S boundary causes G2 arrest

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF01919534

Inhibition of replicon initiation in human cells following stabilization of topoisomerase-DNA cleavable complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Restoration of radiation resistance in ataxia telangiectasia cells by the introduction of normal human chromosome 11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Radiation effects on DNA synthesis in a defined chromosomal replicon

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF01919534

The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Comparison of kinetics of X-ray-induced cell killing in normal, ataxia telangiectasia and hereditary retinoblastoma fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF01919534

Radioresistant DNA synthesis: an intrinsic feature of ataxia telangiectasia

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF01919534

Formation of nascent DNA molecules during inhibition of replicon initiation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Increased initial levels of chromosome damage and heterogeneous chromosome repair in ataxia telangiectasia heterozygote cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Ataxia telangiectasia: an investigation of the repair defect in the cell line AT5BIVA by plasmid reconstitution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Flow cytometric analysis of X-ray sensitivity in ataxia telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Abnormal processing of transfected plasmid DNA in cells from patients with ataxia telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

X-ray-induced transcriptional activation of c-myc and XRCC1 genes in ataxia telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

DNA-binding protein activated by gamma radiation in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Analysis of mutations caused by DNA double-strand breaks produced by a restriction enzyme in shuttle vector plasmids propagated in ataxia telangiectasia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

The genetic basis of resistance to ionising radiation damage in cultured mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

The study of responses to 'model' DNA breaks induced by restriction endonucleases in cells and cell-free systems: achievements and difficulties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF01919534

Structure and function of type II DNA topoisomerases

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF01919534

Involvement of proliferating cell nuclear antigen (cyclin) in DNA replication in living cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF01919534

Control of the cell cycle

21 January 2018

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12 December 2020

Possible role of chromatin alteration in the radiosensitivity of ataxia-telangiectasia.

1 reference

12 December 2020

Studies in Synthesis of Deoxyribonucleic Acid: Mechanism of Radiation Effect on the Process of Synthesis of Deoxyribonucleic Acid

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12 December 2020

Complementation of the defects of DNA synthesis in irradiated and unirradiated ataxia-telangiectasia cells

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12 December 2020

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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12 December 2020

Yeast replication factor-A functions in the unwinding of the SV40 origin of DNA replication

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12 December 2020

Cell kinetics and radiation biology

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12 December 2020

A mechanism for deletion formation in DNA by human cell extracts: the involvement of short sequence repeats

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12 December 2020

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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12 December 2020

Impairment of V(D)J recombination in double-strand break repair mutants

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12 December 2020

p53 mutations and microsatellite instability in sporadic gastric cancer: when guardians fail

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12 December 2020

The scid mutation in mice causes a general defect in DNA repair

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12 December 2020

Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product

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12 December 2020

Early transcriptional events in cell growth: the Egr family

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12 December 2020

Effects of X-irradiation on cell-cycle progression, induction of chromosomal aberrations and cell killing in ataxia telangiectasia (AT) fibroblasts

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12 December 2020

Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines.

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12 December 2020

Cell death: the significance of apoptosis

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12 December 2020

Cell cycle checkpoints, genetic instability and cancer.

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12 December 2020

Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1

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12 December 2020

DNA damage increases the levels of MDM2 messenger RNA in wtp53 human cells

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12 December 2020

Replication of mammalian DNA in vitro. Evidence for initiation from fiber autoradiography

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12 December 2020

Proliferating cell nuclear antigen is required for DNA excision repair

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12 December 2020

Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains

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12 December 2020

Universal control mechanism regulating onset of M-phase

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12 December 2020

Regulation of the specific DNA binding function of p53

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12 December 2020

The direct effect of x-irradiation on HeLa S3 deoxyribonucleic acid synthesis.

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12 December 2020

Defects in the kinetics of the repair of DNA double-strand breaks and inhibition of DNA synthesis in the ataxia telangiectasia AT5BI-VA cell line: comparison to a corrected hybrid, atxbc

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12 December 2020

Radiation effects on DNA chain growth in mammalian cells.

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12 December 2020

V(D)J recombination and ataxia-telangiectasia: a review

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12 December 2020

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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12 December 2020

Radiation induction of immediate early genes: effectors of the radiation-stress response.

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12 December 2020

Rejoining of X-ray Induced Breaks in the DNA of Leukaemia Cells

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12 December 2020

Ionizing radiation and UV induction of p53 protein by different pathways in ataxia-telangiectasia cells

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12 December 2020

Staurosporine suppresses replicon initiation in mammalian cells

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12 December 2020

Enzymatic restriction of mammalian cell DNA: evidence for double-strand breaks as potentially lethal lesions

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12 December 2020

Murine scid cells complement ataxia-telangiectasia cells and show a normal post-irradiation response of DNA synthesis

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12 December 2020

Wild-type alternatively spliced p53: binding to DNA and interaction with the major p53 protein in vitro and in cells.

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12 December 2020

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

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12 December 2020

Participation of p53 protein in the cellular response to DNA damage

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12 December 2020

Checkpoints: controls that ensure the order of cell cycle events

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12 December 2020

The repair of potentially lethal damage in x-irradiated cultures of normal and ataxia telangiectasia human fibroblasts.

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12 December 2020

Effects of ionizing radiation on DNA replication in cultured mammalian cells

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12 December 2020

Possible role for p34cdc2 kinase in etoposide-induced cell death of Chinese hamster ovary cells

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12 December 2020

Reduced induction of P53 protein by gamma-irradiation in ataxia telangiectasia cells without constitutional mutations in exons 5, 6, 7, and 8 of the p53 gene

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12 December 2020

Initial chromosome damage but not DNA damage is greater in ataxia telangiectasia cells

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12 December 2020

Cell death, chromosome damage and mitotic delay in normal human, ataxia telangiectasia and retinoblastoma fibroblasts after x-irradiation

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12 December 2020

Radiation-stimulated DNA synthesis in cultured mammalian cells

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12 December 2020

Dissociation between radioresistant DNA replication and chromosomal radiosensitivity in ataxia telangiectasia cells

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12 December 2020

Genetic complementation analysis of ataxia telangiectasia and Nijmegen breakage syndrome: a survey of 50 patients

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12 December 2020

Ionizing radiation induces expression and binding activity of the nuclear factor kappa B

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12 December 2020

In vitro phosphorylation of the tumor suppressor gene RB protein by mitosis-specific histone H1 kinase

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12 December 2020

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

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12 December 2020

Delayed Initiation of DNA Synthesis in Irradiated Human Diploid Cells

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12 December 2020

A human nuclear protein with sequence homology to a family of early S phase proteins is required for entry into S phase and for cell division

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12 December 2020

Variations in several responses of HeLa cells to x-irradiation during the division cycle

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12 December 2020

Presence of a potent transcription activating sequence in the p53 protein

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12 December 2020

Coupling M phase and S phase: controls maintaining the dependence of mitosis on chromosome replication

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12 December 2020

Mitotic G 2 delay induced in synchronized human kidney cells by UV and x-irradiation and its relation to DNA strand breakage, repair and transcription

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12 December 2020

p53 is required for radiation-induced apoptosis in mouse thymocytes

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12 December 2020

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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12 December 2020

A critical look at the association of human genetic syndromes with sensitivity to ionizing radiation.

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12 December 2020

Effect of irradiation and theory of role of mitotic delay on the time course of labeling of HeLa S3 cells with tritiated thymidine.

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12 December 2020

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

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12 December 2020

The E2F transcription factor is a cellular target for the RB protein

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12 December 2020

Radiation-induced apoptosis in a murine T-cell hybridoma

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12 December 2020

Clonal chromosome aberrations and genomic instability in X-irradiated human T-lymphocyte cultures

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12 December 2020

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

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12 December 2020

The rejoining of double-strand breaks in DNA by human cell extracts

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12 December 2020

Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.

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12 December 2020

Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage

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12 December 2020

p53 mutations increase resistance to ionizing radiation

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12 December 2020

The contribution of DNA and chromosome repair deficiencies to the radiosensitivity of ataxia-telangiectasia

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12 December 2020

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

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12 December 2020

Evidence that x-irradiation inhibits DNA replicon initiation in Chinese hamster cells

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12 December 2020

Transmission of chromosomal instability after plutonium α-particle irradiation

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12 December 2020

Evidence for DNA double-strand breaks as the critical lesions in yeast cells irradiated with sparsely or densely ionizing radiation under oxic or anoxic conditions.

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12 December 2020

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12 December 2020

Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.

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12 December 2020

The response of ataxia-telangiectasia lymphoblastoid cells to neutron irradiation

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12 December 2020

Transfection of SV40-transformed ataxia-telangiectasia fibroblasts with mouse DNA corrects hypersensitivity to neocarzinostatin and activates fibronectin gene expression

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12 December 2020

Differential effect of ionizing radiation on the expression of cyclin A and cyclin B in HeLa cells

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12 December 2020

The action of caffeine on X-irradiated HeLa cells. I. Delayed inhibition of DNA synthesis

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12 December 2020

X-Ray-Induced Inhibition of DNA Synthesis in Chinese Hamster Ovary, Human HeLa, and Mouse L Cells

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12 December 2020

Ionizing radiation and cell cycle progression in ataxia telangiectasia.

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12 December 2020

Expression cloning of multiple human cDNAs that complement the phenotypic defects of ataxia-telangiectasia group D fibroblasts

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12 December 2020

Creative blocks: cell-cycle checkpoints and feedback controls

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12 December 2020

High spontaneous intrachromosomal recombination rates in ataxia-telangiectasia

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12 December 2020

Response of ataxia telangiectasia cells to restriction endonuclease induced DNA double-strand breaks: I. Cytogenetic characterization

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12 December 2020

Repair and misrepair of site-specific DNA double-strand breaks by human cell extracts

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12 December 2020

cdc2 family kinases phosphorylate a human cell DNA replication factor, RPA, and activate DNA replication

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12 December 2020

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

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12 December 2020

Ionizing radiation activates transcription of the EGR1 gene via CArG elements

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12 December 2020

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

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12 December 2020

Persistent inhibition of DNA synthesis in irradiated rat embryo fibroblasts expressing the oncogenes H-ras plus v-myc derives from inhibition of replicon initiation and is mitigated by staurosporine

1 reference

12 December 2020

Genetic Haplotyping of Ataxia-telangiectasia Families Localizes the Major Gene to an ∼ 850 kb Region on Chromosome 11q23.1.

1 reference

12 December 2020

Genetic heterogeneity in ataxia-telangiectasia studied by cell fusion

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12 December 2020

A derivative of an ataxia-telangiectasia (A-T) cell line with normal radiosensitivity but A-T-like inhibition of DNA synthesis

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12 December 2020

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

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12 December 2020

Wild-type p53 can down-modulate the activity of various promoters

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12 December 2020

Radiation-activated DNA-binding protein constitutively present in ataxia telangiectasia nuclei

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12 December 2020

Genetic complementation of radiation response by 3' untranslated regions (UTR) of RNA.

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12 December 2020

Ataxia-telangiectasia: linkage analysis of chromosome 11q22-23 markers in Turkish families

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12 December 2020

Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes

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12 December 2020

On the nature of a defect in cells from individuals with ataxia-telangiectasia

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12 December 2020

Cyclic x-ray responses in mammalian cells in vitro

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12 December 2020

Rules to replicate by

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12 December 2020

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

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12 December 2020

Alterations in oncogene expression and radiosensitivity in the most frequently used SV40-transformed human skin fibroblasts.

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12 December 2020

Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells

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12 December 2020

The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner

1 reference

12 December 2020

Characterization of a hybrid hamster-human cell line complemented for the ataxia telangiectasia DNA repair defects

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12 December 2020

Stable radioresistance in ataxia-telangiectasia cells containing DNA from normal human cells

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12 December 2020

Characterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication

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12 December 2020

WAF1, a potential mediator of p53 tumor suppression

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12 December 2020

G2/M-phase arrest and release in ataxia telangiectasia and normal cells after exposure to ionizing radiation.

1 reference

12 December 2020

Enhancement of Radiation-Induced Mitotic Inhibition by BUdR Incorporation in L-Cells

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12 December 2020

The molecular basis for cell cycle delays following ionizing radiation: a review

1 reference

12 December 2020

Functional complementation of ataxia-telangiectasia group D (AT-D) cells by microcell-mediated chromosome transfer and mapping of the AT-D locus to the region 11q22-23.

1 reference

12 December 2020

Radiosensivity of mammalian cells. I. Timing and dose-dependence of radiation-induced division delay

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12 December 2020

Delayed appearance of radiation-induced mutations at the Hprt locus in murine hemopoietic cells

1 reference

12 December 2020

Relative contributions of levels of initial DNA damage and repair of double strand breaks to the ionizing radiation-sensitive phenotype of the Chinese hamster cell mutant, XR-V15B. Part I. X-rays

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12 December 2020

Biological consequences of gene regulation after ionizing radiation exposure

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12 December 2020

G1 phase progression: cycling on cue

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12 December 2020

The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro

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12 December 2020

Radiosensitivity in ataxia-telangiectasia: a new explanation

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12 December 2020

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

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12 December 2020

V(D)J recombination in ataxia telangiectasia, Bloom's syndrome, and a DNA ligase I-associated immunodeficiency disorder

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12 December 2020

Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization

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12 December 2020

A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex.

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12 December 2020

mdm2 expression is induced by wild type p53 activity

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12 December 2020

Ordering S phase and M phase in the cell cycle

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12 December 2020

The mdm-2 gene is induced in response to UV light in a p53-dependent manner

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12 December 2020

The retinoblastoma protein is phosphorylated on multiple sites by human cdc2

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12 December 2020

Radioresistant DNA synthesis and human genetic diseases

1 reference

12 December 2020

Cyclin B expression in HeLa cells during the G2 block induced by ionizing radiation

1 reference

12 December 2020

The role of cell cycle progression in cisplatin-induced apoptosis in Chinese hamster ovary cells

1 reference

12 December 2020

A fourth complementation group among ionizing radiation-sensitive Chinese hamster cell mutants defective in DNA double-strand break repair

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12 December 2020

Abnormal retention of X-irradiated ataxia-telangiectasia fibroblasts in G2 phase of the cell cycle: cellular RNA content, chromatin stability and the effects of 3-aminobenzamide.

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12 December 2020

On the Increased Precursor Incorporation into DNA of Irradiated Mammalian Cells

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12 December 2020

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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12 December 2020

Perturbations of cell-cycle progression in γ-irradiated ataxia telangiectasia and Huntington's disease cells detected by DNA flow cytometric analysis

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12 December 2020

Prolonged inhibition by X-rays of DNA synthesis in cells obtained by transformation of primary rat embryo fibroblasts with oncogenes H-ras and v-myc

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12 December 2020

Cellular factors required for multiple stages of SV40 DNA replication in vitro

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12 December 2020

Increased UV-induced SCEs but normal repair of DNA damage in p53-deficient mouse cells

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12 December 2020

The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia

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12 December 2020

Ataxia-telangiectasia: an interdisciplinary approach to pathogenesis

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12 December 2020

Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway

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12 December 2020

Action of radiation on mammalian cells. IV. Reversible mitotic lag in the S3 HeLa cell produced by low doses of x-rays

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12 December 2020

Identification of cellular proteins required for simian virus 40 DNA replication

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12 December 2020

p21 is a universal inhibitor of cyclin kinases

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12 December 2020

Enhanced levels of radiation-induced G2 phase delay in ataxia telangiectasia heterozygotes

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12 December 2020

Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein

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12 December 2020

Radiosensitivity in ataxia-telangiectasia: anomalies in radiation-induced cell cycle delay

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12 December 2020

Comparative study of radiation-induced G2 phase delay and chromatid damage in families with ataxia-telangiectasia.

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12 December 2020

Clinical and genetic features of ataxia-telangiectasia

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12 December 2020

Physical and Genetic Mapping at the ATA/ATC Locus on Chromosome 11q22-23.

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12 December 2020

Genetic and physical mapping of the ataxia-telangiectasia locus on chromosome 11q22-q23.

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12 December 2020

The nature of ataxia-telangiectasia: problems and perspectives

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12 December 2020

Radiation-induced G2 Delay and Spontaneous Chromosome Aberrations in Ataxia-telangiectasia Homozygotes and Heterozygotes.

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12 December 2020

Possible role of chromatin alteration in the radiosensitivity of ataxia-telangiectasia

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12 December 2020

Clinical and genetic features of ataxia-telangiectasia

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12 December 2020

Genetic and physical mapping of the ataxia-telangiectasia locus on chromosome Ilq22-q23.

1 reference

12 December 2020

Genetic haplotyping of ataxia-telangiectasia families localizes the major gene to an ~850 kb region on chromosome 11 q23.1.

1 reference

12 December 2020

V(D)J Recombination and ataxia-telangiectasia: a Review

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01919534

1 reference

16 August 2017

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PubMed ID

8620934