Visualization and manipulation of phosphoinositide dynamics in live cells using engineered protein domains. (Q36808725)

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30 December 2019

review article

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title

Visualization and manipulation of phosphoinositide dynamics in live cells using engineered protein domains (English)

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30 December 2019

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2

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30 December 2019

author name string

Péter Várnai

series ordinal

1

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30 December 2019

publication date

1 May 2007

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30 December 2019

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30 December 2019

volume

455

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30 December 2019

issue

1

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30 December 2019

page(s)

69-82

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Evidence that the inositol phospholipids are necessary for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP.

30 December 2019

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Polarity in intracellular calcium signaling

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Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase

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Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities

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PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

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G-protein signaling through tubby proteins

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A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

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Intracellular delivery of phosphoinositides and inositol phosphates using polyamine carriers

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Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction

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12 December 2020

Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo

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12 December 2020

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

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12 December 2020

The relationship of hormone-sensitive and hormone-insensitive phosphatidylinositol to phosphatidylinositol 4,5-bisphosphate in the WRK-1 cell

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12 December 2020

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling

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12 December 2020

EGF-and NGF-stimulated translocation of cytohesin-1 to the plasma membrane of PC12 cells requires PI 3-kinase activation and a functional cytohesin-1 PH domain

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12 December 2020

How accurately can we image inositol lipids in living cells?

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12 December 2020

Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor

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Decoding of cytosolic calcium oscillations in the mitochondria

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12 December 2020

Phosphatidylinositol 4 phosphate regulates targeting of clathrin adaptor AP-1 complexes to the Golgi

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12 December 2020

Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners.

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12 December 2020

Mammalian phosphatidylinositol transfer proteins: emerging roles in signal transduction and vesicular traffic.

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Ent3p Is a PtdIns(3,5)P2 effector required for protein sorting to the multivesicular body.

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12 December 2020

Targeting of inositol 1,4,5-trisphosphate receptors to the endoplasmic reticulum by multiple signals within their transmembrane domains

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12 December 2020

Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum

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12 December 2020

The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphos

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12 December 2020

An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways

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12 December 2020

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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12 December 2020

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

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12 December 2020

Myo-inositol phosphates from beef brain phosphoinostide.

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12 December 2020

Targeted expression of the inositol 1,4,5-triphosphate receptor (IP3R) ligand-binding domain releases Ca2+ via endogenous IP3R channels

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12 December 2020

Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1

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12 December 2020

Control of calcium signal propagation to the mitochondria by inositol 1,4,5-trisphosphate-binding proteins.

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12 December 2020

Inositol trisphosphate, a novel second messenger in cellular signal transduction

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12 December 2020

Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion

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12 December 2020

Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer

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12 December 2020

Transforming protein of avian sarcoma virus UR2 is associated with phosphatidylinositol kinase activity: possible role in tumorigenesis

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12 December 2020

Mutational analysis of Gbetagamma and phospholipid interaction with G protein-coupled receptor kinase 2

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12 December 2020

Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains

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12 December 2020

Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma

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12 December 2020

Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cells

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12 December 2020

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

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12 December 2020

Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

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12 December 2020

Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components.

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12 December 2020

The role of the phosphoinositides at the Golgi complex

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12 December 2020

Active Arf6 recruits ARNO/cytohesin GEFs to the PM by binding their PH domains.

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12 December 2020

Essential role of phosphoinositide metabolism in synaptic vesicle recycling

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12 December 2020

Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain

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12 December 2020

Imaging phosphoinositide dynamics using GFP-tagged protein domains

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12 December 2020

The FYVE domain of early endosome antigen 1 is required for both phosphatidylinositol 3-phosphate and Rab5 binding. Critical role of this dual interaction for endosomal localization

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12 December 2020

A 15-residue bifunctional element in D-AKAP1 is required for both endoplasmic reticulum and mitochondrial targeting

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12 December 2020

Mitochondrial Ca2+ uptake with and without the formation of high-Ca2+ microdomains

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12 December 2020

Coincidence detection in phosphoinositide signaling.

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12 December 2020

Visualizing PI3 kinase-mediated cell-cell signaling during Dictyostelium development

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12 December 2020

PtdIns(4,5)P2 functions at the cleavage furrow during cytokinesis

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12 December 2020

Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channels

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12 December 2020

Dual effect of beta-adrenergic receptors on mitogen-activated protein kinase. Evidence for a beta gamma-dependent activation and a G alpha s-cAMP-mediated inhibition

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12 December 2020

A novel recombinant hyperaffinity inositol 1,4,5-trisphosphate (IP(3)) absorbent traps IP(3), resulting in specific inhibition of IP(3)-mediated calcium signaling

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12 December 2020

Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools

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12 December 2020

The pleckstrin homology domain of oxysterol-binding protein recognises a determinant specific to Golgi membranes.

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12 December 2020

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

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12 December 2020

Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting.

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12 December 2020

Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells

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12 December 2020

Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains

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12 December 2020

Single cell imaging of PI3K activity and glucose transporter insertion into the plasma membrane by dual color evanescent wave microscopy

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12 December 2020

Distinct Polyphosphoinositide Binding Selectivities for Pleckstrin Homology Domains of GRP1-like Proteins Based on DiglycineVersusTriglycine Motifs

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12 December 2020

Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes

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12 December 2020

A wave of IP3 production accompanies the fertilization Ca2+ wave in the egg of the frog, Xenopus laevis: theoretical and experimental support

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12 December 2020

Phosphatidylinositol 3-Phosphate Recognition by the FYVE Domain

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12 December 2020

Receptor activation alters inner surface potential during phagocytosis

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12 December 2020

Phosphoinositide regulation of the actin cytoskeleton

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12 December 2020

Pleckstrin homology domains: not just for phosphoinositides

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12 December 2020

GTP hydrolysis by ADP-ribosylation factor is dependent on both an ADP-ribosylation factor GTPase-activating protein and acid phospholipids

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12 December 2020

Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

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12 December 2020

Synthesis and biological activity of phospholipase C-resistant analogues of phosphatidylinositol 4,5-bisphosphate.

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12 December 2020

Phospholipase C in Living Cells

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12 December 2020

A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1.

1 reference

12 December 2020

Multiple pools of phosphatidylinositol 4-phosphate detected using the pleckstrin homology domain of Osh2p.

1 reference

12 December 2020

Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor

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12 December 2020

Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase

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12 December 2020

Enzyme secretion and the incorporation of P32 into phospholipides of pancreas slices.

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12 December 2020

Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains

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12 December 2020

New insights into the molecular and cellular workings of the cardiac Na+/Ca2+ exchanger

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12 December 2020

Receptor-mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells

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12 December 2020

Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1.

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12 December 2020

Probing phosphoinositide functions in signaling and membrane trafficking.

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12 December 2020

Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130.

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12 December 2020

Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates.

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12 December 2020

Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains

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12 December 2020

The Effector Domain of Myristoylated Alanine-rich C Kinase Substrate Binds Strongly to Phosphatidylinositol 4,5-Bisphosphate

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12 December 2020

Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors

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12 December 2020

Golgi retention mechanism of beta-1,4-galactosyltransferase. Membrane-spanning domain-dependent homodimerization and association with alpha- and beta-tubulins

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12 December 2020

Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy

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12 December 2020

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12 December 2020

FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P

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12 December 2020

ATP-dependent inositide phosphorylation required for Ca2+-activated secretion

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12 December 2020

PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane

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12 December 2020

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels.

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12 December 2020

10.1007/S00424-007-0270-Y

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17473931%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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