GABA(B) receptors: structure and function (Q36820569)

16 August 2017

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title

GABA(B) receptors: structure and function (English)

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16 August 2017

Piers C Emson

1

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16 August 2017

language of work or name

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1 January 2007

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Progress in Brain Research

16 August 2017

published in

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16 August 2017

volume

160

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16 August 2017

page(s)

43-57

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Hetero-oligomerization between GABAA and GABAB receptors regulates GABAB receptor trafficking

16 August 2017

cites work

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7 January 2021

Ectopically expressed gamma-aminobutyric acid receptor B is functionally down-regulated in isolated lipid raft-enriched membranes

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7 January 2021

gamma-aminobutyric acid type B receptor splice variant proteins GBR1a and GBR1b are both associated with GBR2 in situ and display differential regional and subcellular distribution

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7 January 2021

Molecular structure and physiological functions of GABA(B) receptors

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7 January 2021

Advances in the molecular understanding of GABA(B) receptors.

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7 January 2021

The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor

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7 January 2021

Molecular mechanisms of GABA(B) receptor activation: new insights from the mechanism of action of CGP7930, a positive allosteric modulator.

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7 January 2021

Structural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly folded

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7 January 2021

GABAB receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal cord

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7 January 2021

Multiple GABAB receptors

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7 January 2021

GABAB receptor pharmacology

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7 January 2021

International Union of Pharmacology. XXXIII. Mammalian gamma-aminobutyric acid(B) receptors: structure and function

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7 January 2021

Bicuculline-insensitive gaba receptors on peripheral autonomic nerve terminals

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7 January 2021

Characteristics of GABAB receptor binding sites on rat whole brain synaptic membranes

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7 January 2021

(-)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor.

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7 January 2021

Assembly-dependent surface targeting of the heterodimeric GABAB Receptor is controlled by COPI but not 14-3-3.

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7 January 2021

Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation

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7 January 2021

The expression of GABA(B1) and GABA(B2) receptor subunits in the cNS differs from that in peripheral tissues

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7 January 2021

GABAB receptor modulation of Ca2+ currents in rat sensory neurones by the G protein G(0): antisense oligonucleotide studies

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7 January 2021

Distribution of the GABA(B) receptor subunit gb2 in rat CNS

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7 January 2021

Unravelling the unusual signalling properties of the GABA(B) receptor.

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7 January 2021

Association of GABA(B) receptors and members of the 14-3-3 family of signaling proteins

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7 January 2021

Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression.

1 reference

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7 January 2021

Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines

1 reference

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7 January 2021

Central action of bicuculline

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7 January 2021

A physiological role for GABAB receptors in the central nervous system.

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7 January 2021

The heteromeric GABA-B receptor recognizes G-protein alpha subunit C-termini

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7 January 2021

Phosphinic Acid Analogs of GABA. 2. Selective, Orally Active GABAB Antagonists

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7 January 2021

Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding

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7 January 2021

The RXR-type endoplasmic reticulum-retention/retrieval signal of GABAB1 requires distant spacing from the membrane to function

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Characterization of [(3)H]-CGP54626A binding to heterodimeric GABA(B) receptors stably expressed in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Altered regulation of potassium and calcium channels by GABA(B) and adenosine receptors in hippocampal neurons from mice lacking Galpha(o)

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Floxed allele for conditional inactivation of the GABAB(1) gene

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7 January 2021

3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABAB sites in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Inhibition of GABAB receptor binding by guanyl nucleotides

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Cloning and tissue distribution of novel splice variants of the rat GABAB receptor

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Signal transduction by GABA(B) receptor heterodimers

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7 January 2021

G-protein-coupled receptor heterodimerization modulates receptor function

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7 January 2021

Functional interactions between mu opioid and alpha 2A-adrenergic receptors.

1 reference

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7 January 2021

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

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7 January 2021

GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

1 reference

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7 January 2021

Human gamma-aminobutyric acid type B receptors are differentially expressed and regulate inwardly rectifying K+ channels

1 reference

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7 January 2021

Phaclofen: a peripheral and central baclofen antagonist.

1 reference

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7 January 2021

Closed state of both binding domains of homodimeric mGlu receptors is required for full activity.

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Locking the dimeric GABA(B) G-protein-coupled receptor in its active state.

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Neurochemistry of synaptic transmission in the cerebral cortex

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Role of heteromer formation in GABAB receptor function

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Immunohistochemical localization of GABA(B) receptors in the rat central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Molecular identification of the human GABABR2: cell surface expression and coupling to adenylyl cyclase in the absence of GABABR1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Human GABA(B)R genomic structure: evidence for splice variants in GABA(B)R1 but not GABA(B)R2.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

GABAB receptors couple to G proteins Go, Go* and Gi1 but not to Gi2.

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Identification of a GABAB receptor subunit, gb2, required for functional GABAB receptor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Cloning of a novel G-protein-coupled receptor GPR 51 resembling GABAB receptors expressed predominantly in nervous tissues and mapped proximal to the hereditary sensory neuropathy type 1 locus on chromosome 9

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

My close encounter with GABA(B) receptors

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Morpholin-2-yl-phosphinic acids are potent GABA(B) receptor antagonists in rat brain

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Differing actions of beta-phenyl-GABA and baclofen in the guinea pig isolated ileum

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Alternative splicing generates a novel isoform of the rat metabotropic GABA(B)R1 receptor

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Activation mechanism of the heterodimeric GABA(B) receptor

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Allosteric functioning of dimeric class C G-protein-coupled receptors.

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Immunocytochemical distribution of the GABA(B) receptor splice variants GABA(B) R1a and R1b in the rat CNS and dorsal root ganglia.

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Distribution of GABA(B(1a)), GABA(B(1b)) and GABA(B2) receptor protein in cerebral cortex and thalamus of adult rats

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7 January 2021

Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice

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7 January 2021

Multiple motifs regulate the trafficking of GABA(B) receptors at distinct checkpoints within the secretory pathway

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

N-type Ca2+ channels as scaffold proteins in the assembly of signaling molecules for GABAB receptor effects

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Subtype-selective interaction with the transcription factor CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) regulates cell surface expression of GABA(B) receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Characterization of gamma-aminobutyric acid receptor GABAB(1e), a GABAB(1) splice variant encoding a truncated receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

The GABAB2 subunit is critical for the trafficking and function of native GABAB receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Coupling of GABAB receptor GABAB2 subunit to G proteins: evidence from Xenopus oocyte and baby hamster kidney cell expression system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Mechanisms of allosteric modulation at GABAB receptors by CGP7930 and GS39783: effects on affinities and efficacies of orthosteric ligands with distinct intrinsic properties.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Subcellular distribution of GABA(B) receptor homo- and hetero-dimers.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Cloning and tissue distribution of a novel isoform of the rat GABA(B)R1 receptor subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx

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https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Heterodimerization is required for the formation of a functional GABA(B) receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Heterodimerization of gamma-aminobutyric acid B receptor subunits as revealed by the yeast two-hybrid system.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

Gamma-aminobutyric acid binding to receptor sites in the rat central nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2806%2960004-6

7 January 2021

10.1016/S0079-6123(06)60004-6

Identifiers

DOI

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16 August 2017

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