Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential positron emission tomography agents for imaging estrogen receptors in breast cancer. (Q36848788)

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scientific article published on April 2006

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English	Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential positron emission tomography agents for imaging estrogen receptors in breast cancer.	scientific article published on April 2006

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scholarly article

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19 January 2020

Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential positron emission tomography agents for imaging estrogen receptors in breast cancer (English)

1 reference

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19 January 2020

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based on heuristic

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positron emission tomography

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1

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19 January 2020

author name string

John S Comninos

2

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19 January 2020

Dae Yoon Chi

3

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19 January 2020

Dong Wook Kim

4

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19 January 2020

Kathryn E Carlson

5

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19 January 2020

John A Katzenellenbogen

6

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19 January 2020

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1 April 2006

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19 January 2020

Journal of Medicinal Chemistry

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19 January 2020

49

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19 January 2020

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19 January 2020

2496-2511

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19 January 2020

Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity

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Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERalpha or ERbeta.

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Immunolocalization of Estrogen Receptor β in the Mouse Brain: Comparison with Estrogen Receptor α

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29 September 2017

Advances in the science of estrogen receptor modulation

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29 September 2017

Protective effects of estrogen on the cardiovascular system

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Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators

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Estrogen receptor beta in breast cancer.

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29 September 2017

Selective estrogen receptor modulators: tissue selectivity and differential uterine effects

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Estrogen receptors and endocrine diseases: lessons from estrogen receptor knockout mice.

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Molecular perspectives on selective estrogen receptor modulators (SERMs): progress in understanding their tissue-specific agonist and antagonist actions

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29 September 2017

Estrogen receptor transcription and transactivation: Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer

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29 September 2017

Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist

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Estrogen receptor subtype-selective ligands: asymmetric synthesis and biological evaluation of cis- and trans-5,11-dialkyl- 5,6,11, 12-tetrahydrochrysenes

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The protective effects of estrogen on the cardiovascular system

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29 September 2017

Coronary artery and cultured aortic smooth muscle cells express mRNA for both the classical estrogen receptor and the newly described estrogen receptor beta

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29 September 2017

Molecular basis of agonism and antagonism in the oestrogen receptor

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29 September 2017

The estradiol pharmacophore: ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site

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29 September 2017

Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta

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Nuclear hormone receptors: ligand-activated regulators of transcription and diverse cell responses

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ER beta: identification and characterization of a novel human estrogen receptor

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29 September 2017

Altered ligand binding properties and enhanced stability of a constitutively active estrogen receptor: evidence that an open pocket conformation is required for ligand interaction.

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Photoaffinity labels for estrogen binding proteins of rat uterus.

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A new nucleophilic fluorine-18 labeling method for aliphatic mesylates: reaction in ionic liquids shows tolerance for water

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Significantly enhanced reactivities of the nucleophilic substitution reactions in ionic liquid

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Bridged bicyclic cores containing a 1,1-diarylethylene motif are high-affinity subtype-selective ligands for the estrogen receptor

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1 reference

https://pubmed.ncbi.nlm.nih.gov/16610793

12 December 2020

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Structure-activity relationship of estrogens: a study involving cyclofenyl as the model compound

1 reference

https://pubmed.ncbi.nlm.nih.gov/16610793

12 December 2020

based on heuristic

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Update on estrogen signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/16610793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel structural templates for estrogen-receptor ligands and prospects for combinatorial synthesis of estrogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/16610793

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM0512037

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19 January 2020

1 reference

Europe PubMed Central

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19 January 2020

1 reference

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19 January 2020

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