Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration (Q36861432)

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scientific article published on January 2007

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English	Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration	scientific article published on January 2007

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

Transgenic mice with human mutant genes causing Parkinson's disease and amyotrophic lateral sclerosis provide common insight into mechanisms of motor neuron selective vulnerability to degeneration (English)

1 reference

Europe PubMed Central

16 August 2017

amyotrophic lateral sclerosis

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Parkinson's disease

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based on heuristic

inferred from title

author name string

Lee J Martin

1

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Europe PubMed Central

16 August 2017

publication date

1 January 2007

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Europe PubMed Central

16 August 2017

Reviews in the Neurosciences

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Europe PubMed Central

16 August 2017

18

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Europe PubMed Central

16 August 2017

2

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Europe PubMed Central

16 August 2017

115-136

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Europe PubMed Central

16 August 2017

Postnatal phenotype and localization of spinal cord V1 derived interneurons

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

CAP interacts with RNA polymerase in solution in the absence of promoter DNA.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity.

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Lessons from models of SOD1-linked familial ALS.

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Staging of brain pathology related to sporadic Parkinson's disease

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Unraveling the mechanisms involved in motor neuron degeneration in ALS

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Senataxin, the yeast Sen1p orthologue: characterization of a unique protein in which recessive mutations cause ataxia and dominant mutations cause motor neuron disease

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Small interfering RNA targeting the PINK1 induces apoptosis in dopaminergic cells SH-SY5Y.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Cross-species characterization of the ALS2 gene and analysis of its pattern of expression in development and adulthood

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

LRRK2 expression linked to dopamine-innervated areas

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Transgenic mice expressing mutant A53T human alpha-synuclein show neuronal dysfunction in the absence of aggregate formation.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Characterization and function of mitochondrial nitric-oxide synthase

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Alpha-synuclein and neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mutations in the gene encoding immunoglobulin mu-binding protein 2 cause spinal muscular atrophy with respiratory distress type 1

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Novel PINK1 mutations in early-onset parkinsonism

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mutations in dynein link motor neuron degeneration to defects in retrograde transport

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

The ubiquitin system

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

alpha-synuclein promotes mitochondrial deficit and oxidative stress

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https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

How do Parkin mutations result in neurodegeneration?

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Human alpha-synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Autophagy as a regulated pathway of cellular degradation

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mitochondrial nitric oxide synthase is not eNOS, nNOS or iNOS.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

The ubiquitin pathway in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Stabilization of alpha-synuclein protein with aging and familial parkinson's disease-linked A53T mutation.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mutant Cu,Zn superoxide dismutases and familial amyotrophic lateral sclerosis: evaluation of oxidative hypotheses

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Motor neurons rapidly accumulate DNA single-strand breaks after in vitro exposure to nitric oxide and peroxynitrite and in vivo axotomy

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

RNA interference as a tool for target validation

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Anatomical localization of leucine-rich repeat kinase 2 in mouse brain

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Senataxin, the ortholog of a yeast RNA helicase, is mutant in ataxia-ocular apraxia 2.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Heterozygous R1101K mutation of the DCTN1 gene in a family with ALS and FTD.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mice, the motor system, and human motor neuron pathology

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Molecular cloning and characterization of mammalian homologues of vesicle-associated membrane protein-associated (VAMP-associated) proteins

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Etiology and pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Parkin-deficient mice are not a robust model of parkinsonism

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Altered excitability of motor neurons in a transgenic mouse model of familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mutant dynactin in motor neuron disease.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Distal spinal and bulbar muscular atrophy caused by dynactin mutation.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Behavioral and neurochemical effects of wild-type and mutated human alpha-synuclein in transgenic mice

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Apoptosis in amyotrophic lateral sclerosis: a review of the evidence.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Do all programmed cell deaths occur via apoptosis?

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Localization of DJ-1 mRNA in the mouse brain.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Power to the people: PubMed Central

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Apoptosis in Parkinson's disease: signals for neuronal degradation

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Distribution of PINK1 and LRRK2 in rat and mouse brain

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

alpha-Synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mouse motor neuron disease caused by truncated SOD1 with or without C-terminal modification.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Cell death and apoptosis regulating proteins in Parkinson's disease--a cautionary note.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Unstable mutants in the peripheral endosomal membrane component ALS2 cause early-onset motor neuron disease

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Progressive spinal axonal degeneration and slowness in ALS2-deficient mice

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Is motoneuronal cell death in amyotrophic lateral sclerosis apoptosis?

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

A familial amyotrophic lateral sclerosis-associated A4V Cu, Zn-superoxide dismutase mutant has a lower Km for hydrogen peroxide. Correlation between clinical severity and the Km value.

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Genetics of Parkinson's disease and biochemical studies of implicated gene products: Commentary

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Upregulation of the pro-apoptotic BH3-only peptide harakiri in spinal neurons of amyotrophic lateral sclerosis patients

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2007.18.2.115

21 January 2018

Identifiers

10.1515/REVNEURO.2007.18.2.115

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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