NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component (Q36888222)

16 August 2017

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component (English)

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16 August 2017

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24

Bruce Beutler

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16 August 2017

Sara Hildebrand

10

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Jamie Russell

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object named as

Jamie Russell

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16 August 2017

Hexin Shi

1

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16 August 2017

Ying Wang

2

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16 August 2017

Xiaohong Li

3

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16 August 2017

Xiaoming Zhan

4

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16 August 2017

Miao Tang

5

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16 August 2017

Maggy Fina

6

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16 August 2017

Lijing Su

7

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16 August 2017

David Pratt

8

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16 August 2017

Chun Hui Bu

9

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16 August 2017

Stephen Lyon

11

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16 August 2017

Lindsay Scott

12

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16 August 2017

Jiexia Quan

13

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16 August 2017

Qihua Sun

14

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16 August 2017

Stephanie Arnett

16

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16 August 2017

Peter Jurek

17

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16 August 2017

Ding Chen

18

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16 August 2017

Vladimir V Kravchenko

19

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16 August 2017

John C Mathison

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16 August 2017

Eva Marie Y Moresco

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16 August 2017

Nancy L Monson

22

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16 August 2017

Richard J Ulevitch

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16 August 2017

language of work or name

English

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publication date

7 December 2015

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16 August 2017

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250-258

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describes a project that uses

16 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4862588/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Mitochondria in the regulation of innate and adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Real-time resolution of point mutations that cause phenovariance in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Mitosis inhibits DNA double-strand break repair to guard against telomere fusions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Microtubule-driven spatial arrangement of mitochondria promotes activation of the NLRP3 inflammasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Cell volume regulation modulates NLRP3 inflammasome activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

NEK7 is essential for centriole duplication and centrosomal accumulation of pericentriolar material proteins in interphase cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Non-canonical inflammasome activation targets caspase-11

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

The inflammasome: an integrated view

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Nek9 is a Plk1-activated kinase that controls early centrosome separation through Nek6/7 and Eg5

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

A role for mitochondria in NLRP3 inflammasome activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

The Nek6 and Nek7 protein kinases are required for robust mitotic spindle formation and cytokinesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Mechanisms of interleukin-1beta release

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Cellular responses to reactive oxygen species-induced DNA damage and aging.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Phenotype-genotype analysis of cryopyrin-associated periodic syndromes (CAPS): description of a rare non-exon 3 and a novel CIAS1 missense mutation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Anakinra therapy for CINCA syndrome with a novel mutation in exon 4 of the CIAS1 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Interleukin-1beta induction of NFkappaB is partially regulated by H2O2-mediated activation of NFkappaB-inducing kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

A mitotic cascade of NIMA family kinases. Nercc1/Nek9 activates the Nek6 and Nek7 kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Isolation and characterization of two evolutionarily conserved murine kinases (Nek6 and nek7) related to the fungal mitotic regulator, NIMA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Nek7 kinase is enriched at the centrosome, and is required for proper spindle assembly and mitotic progression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Experimental autoimmune encephalomyelitis is exacerbated by IL-1 alpha and suppressed by soluble IL-1 receptor

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Nek7 kinase targeting leads to early mortality, cytokinesis disturbance and polyploidy.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

4 September 2018

ENU mutagenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

NEK7 is a centrosomal kinase critical for microtubule nucleation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4862588

Mutational analysis in neonatal-onset multisystem inflammatory disease: Comment on the articles by Frenkel et al and Saito et al

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.3333

Critical role of antigen-specific antibody in experimental autoimmune encephalomyelitis induced by recombinant myelin oligodendrocyte glycoprotein

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26642356

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Protective effect of the interleukin-1 receptor antagonist (IL-1ra) on experimental allergic encephalomyelitis in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26642356

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.3333

1 reference

16 August 2017

1 reference

16 August 2017

PubMed publication ID

26642356

1 reference