microRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress. (Q36890242)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23598416%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

microRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress (English)

1 reference

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29 February 2020

main subject

endoplasmic reticulum

0 references

1 reference

1

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29 February 2020

author name string

L Geng

2

1 reference

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29 February 2020

Y Wang

3

1 reference

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29 February 2020

C-J Sui

4

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29 February 2020

F Xie

5

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29 February 2020

R-X Shen

6

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29 February 2020

W-F Shen

7

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29 February 2020

J-M Yang

8

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29 February 2020

publication date

18 April 2013

1 reference

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29 February 2020

published in

Cell Death and Disease

1 reference

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29 February 2020

volume

4

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29 February 2020

page(s)

e604

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miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer.

29 February 2020

cites work

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The microRNA miR-199a-5p down-regulation switches on wound angiogenesis by derepressing the v-ets erythroblastosis virus E26 oncogene homolog 1-matrix metalloproteinase-1 pathway

29 September 2017

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Chronic alcohol-induced hepatic insulin resistance and endoplasmic reticulum stress ameliorated by peroxisome-proliferator activated receptor-δ agonist treatment

29 September 2017

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Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.

29 September 2017

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Re-expression of miR-199a suppresses renal cancer cell proliferation and survival by targeting GSK-3β.

29 September 2017

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miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo

29 September 2017

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The transcription factor c-Jun protects against sustained hepatic endoplasmic reticulum stress thereby promoting hepatocyte survival

29 September 2017

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Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism

29 September 2017

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MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2

29 September 2017

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Identification of obstructive jaundice-related microRNAs in mouse liver

29 September 2017

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The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families

29 September 2017

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Endoplasmic reticulum stress in liver disease

29 September 2017

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miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines.

29 September 2017

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Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion

29 September 2017

1 reference

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MiR-199a-3p regulates mTOR and c-Met to influence the doxorubicin sensitivity of human hepatocarcinoma cells

29 September 2017

1 reference

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Biting the iron bullet: endoplasmic reticulum stress adds the pain of hepcidin to chronic liver disease

29 September 2017

1 reference

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Physiological and pathological roles for microRNAs in the immune system

29 September 2017

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Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

29 September 2017

1 reference

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Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress

29 September 2017

1 reference

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The expression of Bcl-XL, Bcl-XS and p27Kip1 in topotecan-induced apoptosis in hepatoblastoma HepG2 cell line.

29 September 2017

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DRAM links autophagy to p53 and programmed cell death

29 September 2017

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ER stress: can the liver cope?

29 September 2017

1 reference

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The human transcription factor AP-1 is a mediator of bile acid-induced liver cell apoptosis

29 September 2017

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MicroRNAs: genomics, biogenesis, mechanism, and function

29 September 2017

2 references

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29 September 2017

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Cholestatic liver disease: pathophysiology and therapeutic options

21 January 2018

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

29 September 2017

1 reference

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Activation of the promoters of genes associated with DNA damage, oxidative stress, ER stress and protein malfolding by the bile salt, deoxycholate

29 September 2017

1 reference

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tRNA ligase is required for regulated mRNA splicing in the unfolded protein response

29 September 2017

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Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

29 September 2017

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The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

29 September 2017

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Hepatic injury induced by bile salts: correlation between biochemical and morphological events

27 June 2018

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Cisplatin-induced downregulation of miR-199a-5p increases drug resistance by activating autophagy in HCC cell

27 June 2018

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Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes.

4 September 2018

1 reference

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The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis

4 September 2018

1 reference

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Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins.

4 September 2018

1 reference

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CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury

4 September 2018

1 reference

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Bile salt-induced hepatocyte apoptosis involves epidermal growth factor receptor-dependent CD95 tyrosine phosphorylation

4 September 2018

1 reference

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Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23598416

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDDIS.2013.134

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23598416%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23598416%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23598416%20AND%20SRC:MED&resulttype=core&format=json