Iron increases the susceptibility of multiple myeloma cells to bortezomib. (Q36892625)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23242599%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Iron increases the susceptibility of multiple myeloma cells to bortezomib (English)

1 reference

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20 February 2020

1 reference

Alessandro Campanella

1

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20 February 2020

Francesca Fontana

3

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20 February 2020

Simone Cenci

5

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20 February 2020

Roberto Sitia

7

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20 February 2020

6

Magda Marcatti

1 reference

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20 February 2020

author name string

Paolo Santambrogio

2

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20 February 2020

Michela Frenquelli

4

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20 February 2020

Giovanni Tonon

8

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20 February 2020

Clara Camaschella

9

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20 February 2020

publication date

14 December 2012

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20 February 2020

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20 February 2020

volume

98

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20 February 2020

issue

6

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20 February 2020

page(s)

971-979

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Diagnosis and management of anaemia of chronic disease: current status

20 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

29 September 2017

Human iron transporters

1 reference

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Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1.

29 September 2017

1 reference

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Regulation of cellular iron metabolism

29 September 2017

1 reference

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Ferroportin and iron regulation in breast cancer progression and prognosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2.

29 September 2017

1 reference

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Two to tango: regulation of Mammalian iron metabolism

29 September 2017

1 reference

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Lysosomal proteolysis is the primary degradation pathway for cytosolic ferritin and cytosolic ferritin degradation is necessary for iron exit.

29 September 2017

1 reference

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Iron regulatory proteins: from molecular mechanisms to drug development

29 September 2017

1 reference

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Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

29 September 2017

1 reference

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Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy

29 September 2017

1 reference

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Specific iron chelators determine the route of ferritin degradation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

Iron-dependent degradation of apo-IRP1 by the ubiquitin-proteasome pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

The role of iron regulatory proteins in mammalian iron homeostasis and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

Bortezomib: proteasome inhibition as an effective anticancer therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

Proteasome inhibition in multiple myeloma: therapeutic implication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

Anemia of chronic disease.

29 September 2017

1 reference

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Nitric oxide inhibits H2O2-induced transferrin receptor-dependent apoptosis in endothelial cells: Role of ubiquitin-proteasome pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

A phase 2 study of bortezomib in relapsed, refractory myeloma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

Coordinate transcriptional and translational regulation of ferritin in response to oxidative stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

Endogenous interleukin 6 production in multiple myeloma patients treated with chimeric monoclonal anti-IL6 antibodies indicates the existence of a positive feed-back loop

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

Ceramide-induced intracellular oxidant formation, iron signaling, and apoptosis in endothelial cells: protective role of endogenous nitric oxide

4 September 2018

1 reference

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Overexpression of wild type and mutated human ferritin H-chain in HeLa cells: in vivo role of ferritin ferroxidase activity.

4 September 2018

1 reference

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Sequential evaluation of serum hepcidin in anemic myeloma patients: Study of correlations with myeloma treatment, disease variables, and anemia response

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669455

Nitric oxide, proteasomal function, and iron homeostasis--implications in aging and neurodegenerative diseases

20 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23242599

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Autocrine formation of hepcidin induces iron retention in human monocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23242599

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3324/HAEMATOL.2012.074872

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23242599%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

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20 February 2020

PubMed publication ID

23242599

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23242599%20AND%20SRC:MED&resulttype=core&format=json