Minimizing acetate formation in E. coli fermentations. (Q36898780)

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2 January 2020

review article

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title

Minimizing acetate formation in E. coli fermentations (English)

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2 January 2020

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1

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2 January 2020

author name string

Sofie De Maeseneire

series ordinal

2

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2 January 2020

Wim Soetaert

series ordinal

3

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2 January 2020

Erick Vandamme

series ordinal

4

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2 January 2020

publication date

1 August 2007

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Journal of Industrial Microbiology & Biotechnology

2 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17668256%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

volume

34

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2 January 2020

issue

11

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2 January 2020

page(s)

689-700

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Pyruvate oxidase contributes to the aerobic growth efficiency of Escherichia coli

2 January 2020

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Homofermentative production of D- or L-lactate in metabolically engineered Escherichia coli RR1.

21 January 2018

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12 December 2020

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12 December 2020

Phosphotransacetylase of Escherichia coli B, activation by pyruvate and inhibition by NADH and certain nucleotides

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12 December 2020

Effect of alteration of the acetic acid synthesis pathway on the fermentation pattern of escherichia coli

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12 December 2020

Overcoming acetate in Escherichia coli recombinant protein fermentations

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12 December 2020

Modulation of gene expression made easy

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12 December 2020

Effect of inactivation of nuo and ackA-pta on redistribution of metabolic fluxes in Escherichia coli.

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12 December 2020

High cell density fed-batch cultivation of Escherichia coli using exponential feeding combined with pH-stat

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12 December 2020

Acetate metabolism in a pta mutant of Escherichia coli W3110: importance of maintaining acetyl coenzyme A flux for growth and survival

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12 December 2020

Effect of growth rate reduction and genetic modifications on acetate accumulation and biomass yields in Escherichia coli

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12 December 2020

Control of fed-batch fermentations

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12 December 2020

The effect of NAPRTase overexpression on the total levels of NAD, the NADH/NAD+ ratio, and the distribution of metabolites in Escherichia coli

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12 December 2020

Efficient succinic acid production from glucose through overexpression of pyruvate carboxylase in an Escherichia coli alcohol dehydrogenase and lactate dehydrogenase mutant

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12 December 2020

Scale-up of dialysis fermentation for high cell density cultivation of Escherichia coli

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12 December 2020

A predictive and feedback control algorithm maintains a constant glucose concentration in fed-batch fermentations

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12 December 2020

Tunable promoters in systems biology

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12 December 2020

Response to Hammer et al.: Tuning genetic control--importance of thorough promoter characterization versus generating promoter diversity

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12 December 2020

Analysis of Escherichia coli anaplerotic metabolism and its regulation mechanisms from the metabolic responses to altered dilution rates and phosphoenolpyruvate carboxykinase knockout

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12 December 2020

Latent pathway activation and increased pathway capacity enable Escherichia coli adaptation to loss of key metabolic enzymes

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12 December 2020

Artificial promoters for metabolic optimization

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12 December 2020

Acetate metabolism by Escherichia coli in high-cell-density fermentation

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12 December 2020

Pyruvate kinase: current status of regulatory and functional properties

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12 December 2020

Acetyl-CoA synthetase overexpression in Escherichia coli demonstrates more efficient acetate assimilation and lower acetate accumulation: a potential tool in metabolic engineering

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12 December 2020

High cell density and high-productivity microbial fermentation

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12 December 2020

Regulation of acetyl coenzyme A synthetase in Escherichia coli.

1 reference

12 December 2020

Metabolic flux analysis for a ppc mutant Escherichia coli based on 13C-labelling experiments together with enzyme activity assays and intracellular metabolite measurements.

1 reference

12 December 2020

Influence of acetic acid on the growth of Escherichia coli K12 during high-cell-density cultivation in a dialysis reactor.

1 reference

12 December 2020

Overproduction of recombinant ribulose 1,5-bisphosphate carboxylase/oxygenase from Synechococcus sp. strain PCC6301 in glucose-controlled high-cell-density fermentations by Escherichia coli K-12

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12 December 2020

Engineering Escherichia coli for efficient conversion of glucose to pyruvate

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12 December 2020

Metabolic engineering through cofactor manipulation and its effects on metabolic flux redistribution in Escherichia coli

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12 December 2020

Increased recombinant protein production in Escherichia coli strains with overexpressed water-forming NADH oxidase and a deleted ArcA regulatory protein

1 reference

12 December 2020

A synthetic promoter library for constitutive gene expression in Lactobacillus plantarum

1 reference

12 December 2020

Metabolic characterisation of E. coli citrate synthase and phosphoenolpyruvate carboxylase mutants in aerobic cultures.

1 reference

12 December 2020

Tuning genetic control through promoter engineering

1 reference

12 December 2020

Synthetic promoter libraries--tuning of gene expression

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12 December 2020

Reduction of aerobic acetate production by Escherichia coli.

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12 December 2020

Overflow metabolism in Escherichia coli during steady-state growth: transcriptional regulation and effect of the redox ratio

1 reference

12 December 2020

Alteration of growth yield by overexpression of phosphoenolpyruvate carboxylase and phosphoenolpyruvate carboxykinase in Escherichia coli

1 reference

12 December 2020

An integrated metabolic modeling approach to describe the energy efficiency of Escherichia coli fermentations under oxygen-limited conditions: Cellular energetics, carbon flux, and acetate production.

1 reference

12 December 2020

Redistribution of metabolic fluxes in the central aerobic metabolic pathway of E. coli mutant strains with deletion of the ackA-pta and poxB pathways for the synthesis of isoamyl acetate

1 reference

12 December 2020

Transcriptional and metabolic response of recombinant Escherichia coli to spatial dissolved oxygen tension gradients simulated in a scale-down system

1 reference

12 December 2020

Metabolic characteristics of an isocitrate dehydrogenase defective derivative of escherichia coli BL21(DE3)

1 reference

12 December 2020

On-line detection of acetate formation in Escherichia coli cultures using dissolved oxygen responses to feed transients

1 reference

12 December 2020

Proposed mechanism of acetate accumulation in two recombinant Escherichia coli strains during high density fermentation

1 reference

12 December 2020

The physiological effects and metabolic alterations caused by the expression of Rhizobium etli pyruvate carboxylase in Escherichia coli

1 reference

12 December 2020

Expression of ptsG encoding the major glucose transporter is regulated by ArcA in Escherichia coli

1 reference

12 December 2020

Physiological response of central metabolism in Escherichia coli to deletion of pyruvate oxidase and introduction of heterologous pyruvate carboxylase

1 reference

12 December 2020

Avoiding acetate accumulation in Escherichia coli cultures using feedback control of glucose feeding

1 reference

12 December 2020

Escherichia coli CreBC is a global regulator of gene expression that responds to growth in minimal media

1 reference

12 December 2020

Metabolic responses to substrate futile cycling in Escherichia coli.

1 reference

12 December 2020

Control of metabolic interconversion of isocitrate dehydrogenase between the catalytically active and inactive forms in Escherichia coli

1 reference

12 December 2020

Are growth rates of Escherichia coli in batch cultures limited by respiration?

1 reference

12 December 2020

Cloning, characterization, and functional expression of acs, the gene which encodes acetyl coenzyme A synthetase in Escherichia coli

1 reference

12 December 2020

The glycolytic flux in Escherichia coli is controlled by the demand for ATP.

1 reference

12 December 2020

Determination of the maximum specific uptake capacities for glucose and oxygen in glucose-limited fed-batch cultivations of Escherichia coli

1 reference

12 December 2020

Metabolic flux analysis of Escherichia coli deficient in the acetate production pathway and expressing the Bacillus subtilis acetolactate synthase

1 reference

12 December 2020

High cell-density culture of Escherichia coli

1 reference

12 December 2020

Metabolic flux ratio analysis of genetic and environmental modulations of Escherichia coli central carbon metabolism.

1 reference

12 December 2020

Genetic and biochemical analyses of Escherichia coli strains having a mutation in the structural gene (poxB) for pyruvate oxidase.

1 reference

12 December 2020

Expression of Escherichia coli pyruvate oxidase (PoxB) depends on the sigma factor encoded by the rpoS(katF) gene.

1 reference

12 December 2020

Effect of a pyruvate kinase (pykF-gene) knockout mutation on the control of gene expression and metabolic fluxes in Escherichia coli.

1 reference

12 December 2020

Acetic acid formation in Escherichia coli fermentation

1 reference

12 December 2020

Inverse metabolic engineering: A strategy for directed genetic engineering of useful phenotypes.

1 reference

12 December 2020

Maintaining rapid growth in moderate-density Escherichia coli fermentations

1 reference

12 December 2020

Activation of Escherichia coli pyruvate oxidase enhances the oxidation of hydroxyethylthiamin pyrophosphate

1 reference

12 December 2020

Metabolic flux responses to pyruvate kinase knockout in Escherichia coli

1 reference

12 December 2020

Flux analysis and control of the central metabolic pathways in Escherichia coli

1 reference

12 December 2020

A balanced DO-stat and its application to the control of acetic acid excretion by recombinant Escherichia coli.

1 reference

12 December 2020

The effect of increasing NADH availability on the redistribution of metabolic fluxes in Escherichia coli chemostat cultures

1 reference

12 December 2020

Characterization and evaluation of a pta (phosphotransacetylase) negative mutant of Escherichia coli HB101 as production host of foreign lipase

1 reference

12 December 2020

Enzymatic phosphorylation of acetate

1 reference

12 December 2020

Effect of a single-gene knockout on the metabolic regulation in Escherichia coli for D-lactate production under microaerobic condition

1 reference

12 December 2020

Glucose-stat, a glucose-controlled continuous culture

1 reference

12 December 2020

Metabolic engineering of aerobic succinate production systems in Escherichia coli to improve process productivity and achieve the maximum theoretical succinate yield

1 reference

12 December 2020

Glucose catabolism of Escherichia coli strains with increased activity and altered regulation of key glycolytic enzymes

1 reference

12 December 2020

Metabolic flux analysis for succinic acid production by recombinant Escherichia coli with amplified malic enzyme activity

1 reference

12 December 2020

High-cell-density cultivation of microorganisms

1 reference

12 December 2020

Metabolic engineering of Escherichia coli: increase of NADH availability by overexpressing an NAD(+)-dependent formate dehydrogenase

1 reference

12 December 2020

Control of carbon flux to acetate excretion during growth of Escherichia coli in batch and continuous cultures.

1 reference

12 December 2020

Enhanced production of human epidermal growth factor by a recombinant Escherichia coli integrated with in situ exchange of acetic acid by macroporous ion-exchange resin

1 reference

12 December 2020

Dynamic modeling of the central carbon metabolism of Escherichia coli

1 reference

12 December 2020

The effect of pfl gene knockout on the metabolism for optically pure D-lactate production by Escherichia coli.

1 reference

12 December 2020

Knockout of the ptsG gene in Escherichia coli and cultural characterization of the mutants

1 reference

12 December 2020

Steady-state modelling of metabolic flux between the tricarboxylic acid cycle and the glyoxylate bypass in Escherichia coli.

1 reference

12 December 2020

Identification and characterization of the ackA (acetate kinase A)-pta (phosphotransacetylase) operon and complementation analysis of acetate utilization by an ackA-pta deletion mutant of Escherichia coli

1 reference

12 December 2020

Investigation of the TCA cycle and the glyoxylate shunt in Escherichia coli BL21 and JM109 using (13)C-NMR/MS

1 reference

12 December 2020

Metabolic engineering of Escherichia coli for enhanced production of succinic acid, based on genome comparison and in silico gene knockout simulation

1 reference

12 December 2020

Recombinant protein expression in high cell density fed-batch cultures of Escherichia coli

1 reference

12 December 2020

Effect of modified glucose uptake using genetic engineering techniques on high-level recombinant protein production in escherichia coli dense cultures

1 reference

12 December 2020

The sequence of spacers between the consensus sequences modulates the strength of prokaryotic promoters

1 reference

12 December 2020

Flux adaptations of citrate synthase-deficient Escherichia coli.

1 reference

12 December 2020

Improvement of biomass yield and recombinant gene expression in Escherichia coli by using fructose as the primary carbon source

1 reference

12 December 2020