CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS. (Q36899833)

17 August 2017

CD4+ T cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS. (English)

1 reference

amyotrophic lateral sclerosis

17 August 2017

1 reference

5

Stanley H Appel

1 reference

17 August 2017

David R Beers

1

1 reference

17 August 2017

Jenny S Henkel

series ordinal

2

1 reference

17 August 2017

Weihua Zhao

series ordinal

3

1 reference

17 August 2017

Jinghong Wang

series ordinal

4

1 reference

17 August 2017

language of work or name

English

0 references

publication date

22 September 2008

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Proceedings of the National Academy of Sciences of the United States of America

17 August 2017

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17 August 2017

105

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17 August 2017

40

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17 August 2017

15558-15563

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Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Variations in promoter activity reveal a differential expression and physiology of glutamate transporters by glia in the developing and mature CNS.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

ALS: a disease of motor neurons and their nonneuronal neighbors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Onset and progression in inherited ALS determined by motor neurons and microglia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Control of microglial neurotoxicity by the fractalkine receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Microglial phenotype: is the commitment reversible?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Controlled autoimmunity in CNS maintenance and repair: naturally occurring CD4+CD25+ regulatory T-Cells at the crossroads of health and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Therapeutic T cell-based vaccination for neurodegenerative disorders: the role of CD4+CD25+ regulatory T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

CD4-positive T cell-mediated neuroprotection requires dual compartment antigen presentation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Inflammatory processes in amyotrophic lateral sclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Inflammation in neurodegenerative disease--a double-edged sword

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Amyotrophic lateral sclerosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Local self-renewal can sustain CNS microglia maintenance and function throughout adult life

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Brain-derived neurotrophic factor supports facial motoneuron survival after facial nerve transection in immunodeficient mice.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Exacerbation of motor neuron disease by chronic stimulation of innate immunity in a mouse model of amyotrophic lateral sclerosis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

CD4+ T, but not CD8+ or B, lymphocytes mediate facial motoneuron survival after facial nerve transection

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547419

T cells contribute to lysophosphatidylcholine-induced macrophage activation and demyelination in the CNS

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0807419105

CNS-derived interleukin-4 is essential for the regulation of autoimmune inflammation and induces a state of alternative activation in microglial cells

21 January 2018

1 reference

12 December 2020

Immune reactivity in a mouse model of familial ALS correlates with disease progression

1 reference

12 December 2020

Cu/Zn superoxide dismutase plays important role in immune response

1 reference

12 December 2020

The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS

1 reference

12 December 2020

Loss of Fas ligand-function improves survival in G93A-transgenic ALS mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0807419105

1 reference

17 August 2017

0 references

1 reference

17 August 2017

PubMed publication ID

18809917

1 reference