Chitosan nanoparticles for oral drug and gene delivery (Q36920450)

17 August 2017

8 references

25 June 2019

6 August 2019

19 September 2019

1 October 2019

16 November 2019

18 November 2019

26 October 2020

30 June 2021

Chitosan nanoparticles for oral drug and gene delivery (English)

1 reference

pharmaceutical preparation

17 August 2017

0 references

1 reference

PubMed

biomedical investigative technique

6 August 2019

1 reference

19 September 2019

1 reference

1 October 2019

macromolecular substance

1 reference

16 November 2019

1 reference

18 November 2019

1 reference

26 October 2020

1 reference

1 reference

30 June 2021

Kam W Leong

2

0 references

author name string

Katherine Bowman

series ordinal

1

1 reference

PMC publication ID

2426784

17 August 2017

language of work or name

English

0 references

publication date

1 January 2006

1 reference

International Journal of Nanomedicine

17 August 2017

10 references

17 August 2017

25 June 2019

6 August 2019

19 September 2019

1 October 2019

16 November 2019

18 November 2019

1 June 2020

26 October 2020

30 June 2021

1

1 reference

17 August 2017

2

1 reference

17 August 2017

117-128

1 reference

Effectiveness of submicron-sized, chitosan-coated liposomes in oral administration of peptide drugs

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Synergistic effect of poly(ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Transmucosal macromolecular drug delivery.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

An investigation on the physicochemical properties of chitosan/DNA polyelectrolyte complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Metalloproteinase and cytokine production by THP-1 macrophages following exposure to chitosan-DNA nanoparticles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Trimethylated chitosan as polymeric absorption enhancer for improved peroral delivery of peptide drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

The depolymerization of chitosan: effects on physicochemical and biological properties

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

The effect of the degree of chitosan deacetylation on the efficiency of gene transfection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Transfection of mEpo gene to intestinal epithelium in vivo mediated by oral delivery of chitosan-DNA nanoparticles.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Permeation enhancing polymers in oral delivery of hydrophilic macromolecules: thiomer/GSH systems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

The Gene Pill and its therapeutic applications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Polymeric microspheres for drug delivery to the oral cavity: an in vitro evaluation of mucoadhesive potential.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Chitosan-based gastrointestinal delivery systems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Galactosylated low molecular weight chitosan as DNA carrier for hepatocyte-targeting

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Challenges for the oral delivery of macromolecules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transport.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Chitosan and its derivatives as intestinal absorption enhancers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Chitosan: some pharmaceutical and biological aspects--an update

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Exploiting M cells for drug and vaccine delivery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Immune effects and mechanisms of action of CpG motifs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Carbohydrate biopolymers enhance antibody responses to mucosally delivered vaccine antigens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Polymeric nano- and microparticles for the oral delivery of peptides and peptidomimetics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Chitosan and its derivatives: potential excipients for peroral peptide delivery systems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

DNA and RNA-based vaccines: principles, progress and prospects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Enhancement of nasal absorption of insulin using chitosan nanoparticles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

DNA-polycation nanospheres as non-viral gene delivery vehicles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Chitosans as absorption enhancers for poorly absorbable drugs 2: mechanism of absorption enhancement

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Alveolar macrophage priming by intravenous administration of chitin particles, polymers of N-acetyl-D-glucosamine, in mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Gastrointestinal uptake of biodegradable microparticles: effect of particle size

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Targeting to intestinal M cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Transfection efficiency of chitosan vectors: effect of polymer molecular weight and degree of deacetylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Evaluation of mucoadhesive properties of chitosan microspheres prepared by different methods

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Uptake of chitosan and associated insulin in Caco-2 cell monolayers: a comparison between chitosan molecules and chitosan nanoparticles.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

A pH-sensitive polymer that enhances cationic lipid-mediated gene transfer

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Atomic force microscopy of gastric mucin and chitosan mucoadhesive systems.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Chitosans as absorption enhancers for poorly absorbable drugs. 1: Influence of molecular weight and degree of acetylation on drug transport across human intestinal epithelial (Caco-2) cells

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

The enzymatic degradation and swelling properties of chitosan matrices with different degrees of N-acetylation

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Improved synthesis and in vitro characterization of chitosan-thioethylamidine conjugate

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Pharmacological activity of peroral chitosan-insulin nanoparticles in diabetic rats

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Thiolated chitosans: development and in vitro evaluation of a mucoadhesive, permeation enhancing oral drug delivery system

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Positively charged nanoparticles for improving the oral bioavailability of cyclosporin-A.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Interactions of phospholipid bilayer with chitosan: effect of molecular weight and pH.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Intestinal absorption of octreotide using trimethyl chitosan chloride: studies in pigs

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

In vitro degradation of chitosan by a commercial enzyme preparation: effect of molecular weight and degree of deacetylation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Positively charged gelatin microspheres as gastric mucoadhesive drug delivery system for eradication of H. pylori

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Intestinal absorption of octreotide: N-trimethyl chitosan chloride (TMC) ameliorates the permeability and absorption properties of the somatostatin analogue in vitro and in vivo.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Effect of chitosan on epithelial permeability and structure

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Oral gene delivery with chitosan--DNA nanoparticles generates immunologic protection in a murine model of peanut allergy.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Enhancement of paracellular drug transport with highly quaternized N-trimethyl chitosan chloride in neutral environments: in vitro evaluation in intestinal epithelial cells (Caco-2).

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Mucoadhesive polymers as platforms for peroral peptide delivery and absorption: synthesis and evaluation of different chitosan-EDTA conjugates

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2426784

Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2)

4 September 2018

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

Synthesis and in vitro evaluation of chitosan-EDTA-protease-inhibitor conjugates which might be useful in oral delivery of peptides and proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

Generation of Toxoplasma gondii GRA1 protein and DNA vaccine loaded chitosan particles: preparation, characterization, and preliminary in vivo studies

31 March 2020

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

Myeloablation is not required to select and maintain expression of the drug-resistance gene, mutant MGMT, in primary and secondary recipients

31 March 2020

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

Chitin biotechnology applications

31 March 2020

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

Mucoadhesive polymers in peroral peptide drug delivery. VI. Carbomer and chitosan improve the intestinal absorption of the peptide drug buserelin in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery

31 March 2020

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

Transport of membrane-bound macromolecules by M cells in follicle-associated epithelium of rabbit Peyer's patch

31 March 2020

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

Characterization of binding and TNF-alpha-inducing ability of chitosans on monocytes: the involvement of CD14

31 March 2020

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

Chitosans as absorption enhancers of poorly absorbable drugs. 3: Influence of mucus on absorption enhancement

31 March 2020

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

Evaluation of the mucoadhesive properties of N-trimethyl chitosan chloride

31 March 2020

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

In vitro degradation of chitosan by bacterial enzymes from rat cecal and colonic contents

31 March 2020

1 reference

https://api.crossref.org/works/10.2147%2FNANO.2006.1.2.117

10.2147/NANO.2006.1.2.117

31 March 2020

Identifiers

DOI

1 reference

17 August 2017

1 reference

PMC publication ID

2426784

17 August 2017

PubMed publication ID

17722528

1 reference

PMC publication ID

2426784