Discovery and development of sulforaphane as a cancer chemopreventive phytochemical (Q36920762)

17 August 2017

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title

Discovery and development of sulforaphane as a cancer chemopreventive phytochemical (English)

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17 August 2017

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Yuesheng Zhang

1

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PubMed ID

17723168

17 August 2017

Li Tang

series ordinal

2

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17 August 2017

1 September 2007

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Acta Pharmacologica Sinica

17 August 2017

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17 August 2017

28

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17 August 2017

1343-1354

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17 August 2017

9

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https://scigraph.springernature.com/pub.10.1111/j.1745-7254.2007.00679.x

17 August 2017

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cites work

Botanicals in cancer chemoprevention

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https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Role of chemopreventive agents in cancer therapy

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Chemoprotection by sulforaphane: keep one eye beyond Keap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Antioxidant functions of sulforaphane: a potent inducer of Phase II detoxication enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Chemoprotection against cancer by induction of phase 2 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Rapid detection of inducers of enzymes that protect against carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

The chemical diversity and distribution of glucosinolates and isothiocyanates among plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Heating decreases epithiospecifier protein activity and increases sulforaphane formation in broccoli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Selective increase of the potential anticarcinogen 4-methylsulphinylbutyl glucosinolate in broccoli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo[4,5-f]quinoline in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Sulforaphane and quercetin modulate PhIP-DNA adduct formation in human HepG2 cells and hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Induction of cytochrome P450, generation of oxidative stress and in vitro cell-transforming and DNA-damaging activities by glucoraphanin, the bioprecursor of the chemopreventive agent sulforaphane found in broccoli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Sulforaphane modulates cell cycle and apoptosis in transformed and non-transformed human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by sulforaphane is associated with induction of p21CIP1 and inhibition of expression of cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Sulforaphane increases the efficacy of doxorubicin in mouse fibroblasts characterized by p53 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Combination of doxorubicin and sulforaphane for reversing doxorubicin-resistant phenotype in mouse fibroblasts with p53Ser220 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Reactive oxygen species-related induction of multidrug resistance-associated protein 2 expression in primary hepatocytes exposed to sulforaphane

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Efficacy of sulforaphane in eradicating Helicobacter pylori in human gastric xenografts implanted in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Absorption/metabolism of sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Role of glutathione in the accumulation of anticarcinogenic isothiocyanates and their glutathione conjugates by murine hepatoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

High cellular accumulation of sulphoraphane, a dietary anticarcinogen, is followed by rapid transporter-mediated export as a glutathione conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1745-7254.2007.00679.X

Isolation of sulforaphane from hoary cress (Lepidium draba L.)

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.1135/CCCC19592429

Identifiers

DOI

10.1111/J.1745-7254.2007.00679.X

1 reference

PubMed ID

17723168

Dimensions Publication ID

17 August 2017

0 references

1 reference

PubMed ID

17723168