miRNA genetic alterations in human cancers (Q36922253)

17 August 2017

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title

miRNA genetic alterations in human cancers (English)

1 reference

17 August 2017

Antonis Giannakakis

1

1 reference

17 August 2017

George Coukos

2

1 reference

17 August 2017

Artemis Hatzigeorgiou

3

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17 August 2017

Raphael Sandaltzopoulos

4

1 reference

17 August 2017

Lin Zhang

5

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17 August 2017

language of work or name

English

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publication date

1 September 2007

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Expert Opinion on Biological Therapy

17 August 2017

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17 August 2017

7

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17 August 2017

9

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17 August 2017

1375-1386

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

17 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNA maturation: stepwise processing and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Identification of novel genes coding for small expressed RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Identification of tissue-specific microRNAs from mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Vertebrate microRNA genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The microRNAs of Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Ribo-gnome: the big world of small RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

miRBase: microRNA sequences, targets and gene nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Phylogenetic shadowing and computational identification of human microRNA genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Identification of hundreds of conserved and nonconserved human microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Fast and effective prediction of microRNA/target duplexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Prediction of mammalian microRNA targets

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Specificity of microRNA target selection in translational repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Principles of microRNA-target recognition

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Combinatorial microRNA target predictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

21 January 2018

Human MicroRNA targets

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

A combined computational-experimental approach predicts human microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNAs and the hallmarks of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

A sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Real-time quantification of microRNAs by stem-loop RT-PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Real-time expression profiling of microRNA precursors in human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The colorectal microRNAome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Microarray-based, high-throughput gene expression profiling of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNA gene expression deregulation in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

A microRNA expression signature of human solid tumors defines cancer gene targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The role of microRNA genes in papillary thyroid carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Extensive modulation of a set of microRNAs in primary glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

c-Myc-regulated microRNAs modulate E2F1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Accumulation of miR-155 and BIC RNA in human B cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Expression profiling identifies microRNA signature in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Increased expression of microRNA-155 in Epstein-Barr virus transformed lymphoblastoid cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

microRNAs exhibit high frequency genomic alterations in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNAs and chromosomal abnormalities in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Identification of mammalian microRNA host genes and transcription units

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

EST analyses predict the existence of a population of chimeric microRNA precursor-mRNA transcripts expressed in normal human and mouse tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Mammalian microRNAs derived from genomic repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Alu elements within human mRNAs are probable microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

21 January 2018

Genomics of microRNA.

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Identification of microRNAs of the herpesvirus family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

RNA polymerase III transcribes human microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Principles of micro-RNA production and maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The nuclear RNase III Drosha initiates microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The Microprocessor complex mediates the genesis of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The Drosha-DGCR8 complex in primary microRNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

A novel method to detect functional microRNA targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Human let-7 stem-loop precursors harbor features of RNase III cleavage products

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Sequence requirements for micro RNA processing and function in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Nuclear export of microRNA precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Structural requirements for pre-microRNA binding and nuclear export by Exportin 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Role for a bidentate ribonuclease in the initiation step of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Single processing center models for human Dicer and bacterial RNase III

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

microRNA-guided posttranscriptional gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Impaired microRNA processing enhances cellular transformation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNAs direct rapid deadenylation of mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Inhibition of translational initiation by Let-7 MicroRNA in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Repression of protein synthesis by miRNAs: how many mechanisms?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

microRNA target predictions across seven Drosophila species and comparison to mammalian targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

miR-15 and miR-16 induce apoptosis by targeting BCL2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

miR-15a and miR-16-1 down-regulation in pituitary adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

RAS is regulated by the let-7 microRNA family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

The human let-7a-3 locus contains an epigenetically regulated microRNA gene with oncogenic function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Rapid alteration of microRNA levels by histone deacetylase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Sequence variations of microRNAs in human cancer: alterations in predicted secondary structure do not affect processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

An E2F/miR-20a autoregulatory feedback loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: evidence for stage-specific events

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

bic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

T cell activation induces a noncoding RNA transcript sensitive to inhibition by immunosuppressant drugs and encoded by the proto-oncogene, BIC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

High expression of B-cell receptor inducible gene BIC in all subtypes of Hodgkin lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNA-155 is induced during the macrophage inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Regulation of the germinal center response by microRNA-155

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNA-155 regulates human angiotensin II type 1 receptor expression in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Competition for RISC binding predicts in vitro potency of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

Noise amidst the silence: off-target effects of siRNAs?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.9.1375

10.1517/14712598.7.9.1375

21 January 2018

Identifiers

DOI

1 reference

17 August 2017

1 reference