Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors. (Q36925593)

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27 December 2019

title

Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors (English)

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27 December 2019

3

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6

David Baltimore

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author name string

Dong Sung An

1

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F Xiao-Feng Qin

2

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Si Hua Mao

4

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Sam K P Kung

5

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Irvin S Y Chen

7

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publication date

17 July 2006

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27 December 2019

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volume

14

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issue

4

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page(s)

494-504

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Stable RNA interference: comparison of U6 and H1 promoters in endothelial cells and in mouse brain.

27 December 2019

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DNA constructs designed to produce short hairpin, interfering RNAs in transgenic mice sometimes show early lethality and an interferon response.

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29 September 2017

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29 September 2017

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29 September 2017

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Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

29 September 2017

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29 September 2017

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29 September 2017

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Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

29 September 2017

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Activation of the interferon system by short-interfering RNAs

29 September 2017

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29 September 2017

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MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

29 September 2017

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Inhibition of HIV-1 by lentiviral vector-transduced siRNAs in T lymphocytes differentiated in SCID-hu mice and CD34+ progenitor cell-derived macrophages

29 September 2017

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Expression profiling reveals off-target gene regulation by RNAi

29 September 2017

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siRNAs can function as miRNAs

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro

29 September 2017

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Alu-linked hairpins efficiently mediate RNA interference with less toxicity than do H1-expressed short hairpin RNAs.

4 September 2018

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Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

4 September 2018

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U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells.

4 September 2018

1 reference

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Induction of an interferon response by RNAi vectors in mammalian cells

4 September 2018

1 reference

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10.1016/J.YMTHE.2006.05.015

4 December 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16844419%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

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27 December 2019

PubMed publication ID

16844419

1 reference